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Copper is required for oncogenic BRAF signalling and tumorigenesis.
Brady DC, Crowe MS, Turski ML, Hobbs GA, Yao X, Chaikuad A, Knapp S, Xiao K, Campbell SL, Thiele DJ, Counter CM
Nature. 2014 Apr 9. doi: 10.1038/nature13180.
PubMed Article

Plasmids from Article

ID Plasmid  
53156pBABEbleo-Flag-BRAFV600E
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53157pWZLblasti-CTR1
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53158pWZLblasti-CTR1M154A
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53159pGEX6P1-HA-MEK1
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53161pWZLblasti-HA-MEK1
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53163pGEX6P1-HA-MEK1 CBM
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53164pGEX6P1-HA-MEK1 C121S
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53165pWZLblasti-HA-MEK1 C121S
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53166pGEX6P1-HA-MEK5
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53167pWZLblasti-HA-MEK5
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53168pGEX6P1-HA-MEK5 CBM-E
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53169pWZLblasti-HA-MEK5 CBM-E
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53170pGEX4T3-HA-ERK2 K54R
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53171pGEX6P1-HA-ERK5 K84R
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53172pWZLblasti-HA-ERK2 R67S
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53173pWZLblasti-HA-ERK2 D321N
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53174pWZLblasti-HA-ERK2 GOF
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53175pWZLblasti-HA-ERK5
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53176pBABEpuro-HA-MEK1-MEK5DD
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53177pWZLblasti-HA-MEK1-MEK5DD
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53178pBABEpuro-CMYC T58A
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53179pSUPER-retro-puro-tetO-Mek1-shRNA
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53180pSUPER-retro-puro-tetO-CTR1-shRNA
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53195pBABEpuro-HA-MEK1
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53196pBABEpuro-HA-MEK1 CBM
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53197pBABEpuro-HA-MEK1 C121S
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53198pBABEpuro-HA-MEK5
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53199pBABEpuro-HA-MEK5 CBM-E
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53200pGEX4T3-HA-ERK2 GOF
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53201pGEX4T3-HA-ERK2 R67S
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53202pGEX4T3-HA-ERK2 D321N
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53203pBABEpuro-HA-ERK2 GOF
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