TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.
Zimmermann M, Kibe T, Kabir S, de Lange T
Genes Dev. 2014 Nov 15;28(22):2477-91. doi: 10.1101/gad.251611.114. Epub 2014 Oct 24. PubMed Article
Zimmermann M, Kibe T, Kabir S, de Lange T
Genes Dev. 2014 Nov 15;28(22):2477-91. doi: 10.1101/gad.251611.114. Epub 2014 Oct 24. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 64162 | pLPC-NMYC-mTRF1 | Retroviral vector expressing mouse TRF1 with N-terminal Myc tag |
| 64163 | pLPC-NMYC-mTRF1deltaBLM | Retroviral vector expressing mouse TRF1 lacking BLM-binding motifs with N-terminal Myc tag |
| 64164 | pLPC-MYC-hTRF1 | Retroviral vector expressing human TRF1 with N-terminal MYC tag |
| 64165 | pLPC-NMYC-hTRF1deltaBLM | Retroviral vector expressing human TRF1 delta aa317-374 with N-terminal MYC tag |