Addgene - Philip Leder Lab Plasmids

The Philip Leder Lab has deposited plasmids at Addgene for distribution to academic researchers. Addgene is a non-profit plasmid repository dedicated to improving life science research.

Learn more about research in the Philip Leder Lab.

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Title	Authors
Formin 1-isoform IV deficient cells exhibit defects in cell spreading and focal adhesion formation.	Dettenhofer et al
Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2.	Zhou et al
A bifunctional targeted peptide that blocks HER-2 tyrosine kinase and disables mitochondrial function in HER-2-positive carcinoma cells.	Fantin et al
F16, a mitochondriotoxic compound, triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell.	Fantin et al
Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.	Ecsedy et al
beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland.	Michaelson et al
A novel pro-Arg motif recognized by WW domains.	Bedford et al
RET: a poly A-trap retrovirus vector for reversible disruption and expression monitoring of genes in living cells.	Ishida et al
WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif.	Bedford et al
Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice.	Lane et al
NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice.	Krane et al
Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.	Skoda et al
Dispersion of alpha-like globin genes of the mouse to three different chromosomes.	Leder et al
Trans-acting elements modulate expression of the human c-myc gene in Burkitt lymphoma cells.	Chung et al
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene.	Muller et al
v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid.	Leder et al
Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements.	Ornitz et al
The kit ligand: a cell surface molecule altered in steel mutant fibroblasts.	Flanagan et al
Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells.	Ornitz et al
In situ hybridization reveals co-expression of embryonic and adult alpha globin genes in the earliest murine erythrocyte progenitors.	Leder et al
UAS-ras
Leder Lab Unpublished Plasmids