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Limited Use Label License: piggyBac Limited Use Label License

PIGGYBAC LIMITED USE LABEL LICENSE

This material (“Material”) contains the piggyBac transposon, the rights for which have been exclusively licensed to Transposagen Biopharmaceuticals, Inc. (“Transposagen”) by the University of Notre Dame du Lac (“Notre Dame”). In addition to the terms of the UBMTA, the implementing letter(s) and any other agreements provided to you by Addgene through Addgene’s request process, your use of the piggyBac transposon is further subject to this Limited Use Label License or “LULL.”

BY PURCHASING AND USING THE PIGGYBAC TRANSPOSON-CONTAINING MATERIAL, YOU AGREE TO BE BOUND BY THE TERMS OF THIS LULL.

You are granted a limited, non-exclusive, non-transferable right to use plasmids comprising the piggyBac transposon solely for non-commercial, academic, internal research purposes. All right, title and interest in and to the piggyBac transposon, including, without limitation, all patent, trade secret and other intellectual property rights therein, shall remain in Transposagen, subject to limited right of use expressly granted to the you herein. Specifically, use of the piggyBac transposon and its components is covered by U.S. Pat. No. 6,218,185. Use of the piggyBac transposon and its components that are improvements of those products and methods disclosed in U.S. Pat. No. 6,218,185 may be covered by U.S. Pat. Nos. 6,551,825, 6,962,810, 7,105,343 and/or 8,399,643, as well as pending patent applications.

You shall not sell, lease, license or otherwise transfer the piggyBac transposon (whether purchased or replicated by you), its components (including piggyBac transposase), or materials containing/incorporating the piggyBac transposon to any academic core facilities or any third parties for use or distribution. No right or license to perform commercial activities or services of any kind using the piggyBac transposon is granted by this LULL expressly or by implication. Any use of the piggyBac transposon except for non-commercial, academic internal research requires a license from Transposagen. For license information, please contact Transposagen by phone at 859-428-8561 or by email at [email protected]

Notwithstanding the above, distribution of modified material containing the piggyBac transposon, or other derived material, is permitted only through deposit of such modified material with Addgene. Addgene may distribute such materials solely to other academic and non-profit institutions and solely subject to the terms of an agreement between Transposagen and Addgene. If you desire to use transposase with the Materials, you may contact Transposagen or other licensed vendor..

This LULL shall commence on the date of delivery of this LULL (hereinafter the “Effective Date”) and continue in effect until the earlier of: (1) the date when the Materials have been exhausted; (2) the date of termination of Addgene’s rights to sell the Materials; or (3) the two year anniversary of the delivery date of the Materials. Upon the expiration or termination of this LULL, or upon Addgene’s earlier written request, you shall immediately cease using the Material and promptly return to Addgene all unused Material, or, alternatively, destroy all used Material (whether or not incorporated into other materials), at Recipient’s expense.

Any transfer of the Materials will be subject to a preparation fee as listed in documents provided by Addgene during Addgene’s request process.

Transposagen is not a party to this LULL and has no liability to you or your affiliates under this LULL. Notwithstanding the aforementioned, nothing in this LULL, or any other agreement affecting your use of the piggyBac transposon prevents Transposagen from enforcing its rights under this LULL.

If the terms of this Limited Use Label License conflict with the terms of any other agreements provided to you by Addgene, this Limited Use Label License will control the use of the piggyBac transposon.