Viral Service: Molecular Tools
Tetracycline Transactivators
These AAV encode tetracycline transactivators that can be used with tetracycline (tet)-inducible expression systems.
| ID | Name | Expression System | Activity | Serotype | PI |
|---|---|---|---|---|---|
| 99120 | pAAV-ihSyn1-tTA | Inducible Synapsin promoter (ihSyn) | Expression of the tet-off transactivator (tTA) with a positive feedback loop for amplified tTA expression. | 1 | Gradinaru |
| 99121 | pAAV-ihSyn1-DIO-tTA | Cre-dependent and inducible Synapsin promoter (ihSyn) | Cre-dependent expression of the tet-off transactivator (tTA) with a positive feedback loop for amplified tTA expression. | 1 | Gradinaru |
Tools for Affinity Purification
These AAV encode tools for affinity purification (which can be used for viral TRAP)
| ID | Name | Expression System | Activity | Serotype | PI |
|---|---|---|---|---|---|
| 98747 | pAAV-FLEX-EGFPL10a | EF1a-driven and Cre-dependent | EGFP-tagged ribosomal L10a | 5 | Heintz, Nectow, Schmidt |
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