LT3GEPIR Citations (24)
Originally described in: An optimized microRNA backbone for effective single-copy RNAi.Fellmann C, Hoffmann T, Sridhar V, Hopfgartner B, Muhar M, Roth M, Lai DY, Barbosa IA, Kwon JS, Guan Y, Sinha N, Zuber J Cell Rep. 2013 Dec 26;5(6):1704-13. doi: 10.1016/j.celrep.2013.11.020. Epub 2013 Dec 12. PubMed Journal
Articles Citing LT3GEPIR
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| Global Regulation of the Histone Mark H3K36me2 Underlies Epithelial Plasticity and Metastatic Progression. Yuan S, Natesan R, Sanchez-Rivera FJ, Li J, Bhanu NV, Yamazoe T, Lin JH, Merrell AJ, Sela Y, Thomas SK, Jiang Y, Plesset JB, Miller EM, Shi J, Garcia BA, Lowe SW, Asangani IA, Stanger BZ. Cancer Discov. 2020 Jun;10(6):854-871. doi: 10.1158/2159-8290.CD-19-1299. Epub 2020 Mar 18. PubMed |
| EVI1 activates tumor-promoting transcriptional enhancers in pancreatic cancer. Kim HR, Yim J, Yoo HB, Lee SE, Oh S, Jung S, Hwang CI, Shin DM, Kim T, Yoo KH, Kim YS, Lee HW, Roe JS. NAR Cancer. 2021 Jun 17;3(2):zcab023. doi: 10.1093/narcan/zcab023. eCollection 2021 Jun. PubMed |
| PRC2-Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1-Targeted Therapy via Enhanced Viral Mimicry. Patel AJ, Warda S, Maag JLV, Misra R, Miranda-Roman MA, Pachai MR, Lee CJ, Li D, Wang N, Bayshtok G, Fishinevich E, Meng Y, Wong EWP, Yan J, Giff E, Pappalardi MB, McCabe MT, Fletcher JA, Rudin CM, Chandarlapaty S, Scandura JM, Koche RP, Glass JL, Antonescu CR, Zheng D, Chen Y, Chi P. Cancer Discov. 2022 Sep 2;12(9):2120-2139. doi: 10.1158/2159-8290.CD-21-1671. PubMed |
| Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer. Bartolacci C, Andreani C, Vale G, Berto S, Melegari M, Crouch AC, Baluya DL, Kemble G, Hodges K, Starrett J, Politi K, Starnes SL, Lorenzini D, Raso MG, Solis Soto LM, Behrens C, Kadara H, Gao B, Wistuba II, Minna JD, McDonald JG, Scaglioni PP. Nat Commun. 2022 Jul 26;13(1):4327. doi: 10.1038/s41467-022-31963-4. PubMed |
| Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal. Liu H, Heller-Trulli D, Moore CL. iScience. 2022 Jul 20;25(8):104804. doi: 10.1016/j.isci.2022.104804. eCollection 2022 Aug 19. PubMed |
| The LncRNA LENOX Interacts with RAP2C to Regulate Metabolism and Promote Resistance to MAPK Inhibition in Melanoma. Gambi G, Mengus G, Davidson G, Demesmaeker E, Cuomo A, Bonaldi T, Katopodi V, Malouf GG, Leucci E, Davidson I. Cancer Res. 2022 Dec 16;82(24):4555-4570. doi: 10.1158/0008-5472.CAN-22-0959. PubMed |
| HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation. Scinicariello S, Soderholm A, Schafer M, Shulkina A, Schwartz I, Hacker K, Gogova R, Kalis R, Froussios K, Budroni V, Bestehorn A, Clausen T, Kovarik P, Zuber J, Versteeg GA. Elife. 2023 Mar 24;12:e83159. doi: 10.7554/eLife.83159. PubMed |
| RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status. Dorard C, Madry C, Buhard O, Toifl S, Didusch S, Ratovomanana T, Letourneur Q, Dolznig H, Garnett MJ, Duval A, Baccarini M. Oncogene. 2023 May;42(20):1649-1660. doi: 10.1038/s41388-023-02683-w. Epub 2023 Apr 5. PubMed |
| Asparagine starvation suppresses histone demethylation through iron depletion. Jiang J, Srivastava S, Liu S, Seim G, Claude R, Zhong M, Cao S, Dave U, Kapur R, Mosley AL, Zhang C, Wan J, Fan J, Zhang J. iScience. 2023 Mar 16;26(4):106425. doi: 10.1016/j.isci.2023.106425. eCollection 2023 Apr 21. PubMed |
| Chromatin context-dependent regulation and epigenetic manipulation of prime editing. Li X, Chen W, Martin BK, Calderon D, Lee C, Choi J, Chardon FM, McDiarmid T, Kim H, Lalanne JB, Nathans JF, Shendure J. bioRxiv. 2023 Apr 12:2023.04.12.536587. doi: 10.1101/2023.04.12.536587. Preprint. PubMed |
| USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer. Maier CR, Hartmann O, Prieto-Garcia C, Al-Shami KM, Schlicker L, Vogel FCE, Haid S, Klann K, Buck V, Munch C, Schmitz W, Einig E, Krenz B, Calzado MA, Eilers M, Popov N, Rosenfeldt MT, Diefenbacher ME, Schulze A. Cell Death Differ. 2023 Jul;30(7):1710-1725. doi: 10.1038/s41418-023-01173-6. Epub 2023 May 18. PubMed |
| Gasdermin D-mediated pyroptosis is regulated by AMPK-mediated phosphorylation in tumor cells. Chu X, Xiao X, Wang G, Uosef A, Lou X, Arnold P, Wang Y, Kong G, Wen M, Minze LJ, Li XC. Cell Death Dis. 2023 Jul 26;14(7):469. doi: 10.1038/s41419-023-06013-6. PubMed |
| Precision RNAi using synthetic shRNAmir target sites. Hoffmann T, Hormann A, Corcokovic M, Zmajkovic J, Hinterndorfer M, Salkanovic J, Spreitzer F, Koferle A, Gitschtaler K, Popa A, Oberndorfer S, Andersch F, Schaefer M, Fellner M, Budano N, Ruppert JG, Chetta P, Wurm M, Zuber J, Neumuller RA. Elife. 2023 Aug 8;12:RP84792. doi: 10.7554/eLife.84792. PubMed |
| Target gene regulatory network of miR-497 in angiosarcoma. Benton A, Terwilliger E, Moriarty NM, Liu B, Murphy A, Maluvac H, Shu M, Gartenhaus LE, Janson ND, Pfeffer CM, Utturkar SM, Parkinson EI, Lanman NA, Hanna JA. bioRxiv [Preprint]. 2023 Sep 25:2023.09.24.559218. doi: 10.1101/2023.09.24.559218. PubMed |
| Specialized replication mechanisms maintain genome stability at human centromeres. Scelfo A, Angrisani A, Grillo M, Barnes BM, Muyas F, Sauer CM, Leung CWB, Dumont M, Grison M, Mazaud D, Garnier M, Guintini L, Nelson L, Esashi F, Cortes-Ciriano I, Taylor SS, Dejardin J, Wilhelm T, Fachinetti D. Mol Cell. 2024 Mar 21;84(6):1003-1020.e10. doi: 10.1016/j.molcel.2024.01.018. Epub 2024 Feb 14. PubMed |
| The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium. Niedziolka SM, Datta S, Uspienski T, Baran B, Skarzynska W, Humke EW, Rohatgi R, Niewiadomski P. Commun Biol. 2024 Feb 21;7(1):213. doi: 10.1038/s42003-024-05817-2. PubMed |
| ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer. Xu Y, Yang Y, Wang Z, Sjostrom M, Jiang Y, Tang Y, Cheng S, Deng S, Wang C, Gonzalez J, Johnson NA, Li X, Li X, Metang LA, Mukherji A, Xu Q, Tirado CR, Wainwright G, Yu X, Barnes S, Hofstad M, Chen Y, Zhu H, Hanker AB, Raj GV, Zhu G, He HH, Wang Z, Arteaga CL, Liang H, Feng FY, Wang Y, Wang T, Mu P. Cancer Discov. 2024 Aug 2;14(8):1496-1521. doi: 10.1158/2159-8290.CD-23-0539. PubMed |
| MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability. Jasani N, Xu X, Posorske B, Kim Y, Vera O, Tsai KY, DeNicola GM, Karreth FA. bioRxiv [Preprint]. 2024 Apr 15:2024.04.11.589139. doi: 10.1101/2024.04.11.589139. PubMed |
| Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2. Vogt M, Dudvarski Stankovic N, Cruz Garcia Y, Hofstetter J, Schneider K, Kuybu F, Hauck T, Adhikari B, Hamann A, Rocca Y, Grysczyk L, Martin B, Gebhardt-Wolf A, Wiegering A, Diefenbacher M, Gasteiger G, Knapp S, Saur D, Eilers M, Rosenfeldt M, Erhard F, Vos SM, Wolf E. Gut. 2024 Aug 8;73(9):1509-1528. doi: 10.1136/gutjnl-2023-331519. PubMed |
| The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate. Marin H, Simental E, Allen C, Martin E, Panning B, Al-Sady B, Buchwalter A. bioRxiv [Preprint]. 2024 Jul 11:2024.07.08.602542. doi: 10.1101/2024.07.08.602542. PubMed |
| SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing. Redin E, Sridhar H, Zhan YA, Pereira Mello B, Zhong H, Durani V, Sabet A, Manoj P, Linkov I, Qiu J, Koche RP, de Stanchina E, Astorkia M, Betel D, Quintanal-Villalonga A, Rudin CM. J Hematol Oncol. 2024 Jul 30;17(1):58. doi: 10.1186/s13045-024-01572-3. PubMed |
| Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II. Vidal R, Leen E, Herold S, Muller M, Fleischhauer D, Schulein-Volk C, Papadopoulos D, Roschert I, Uhl L, Ade CP, Gallant P, Bayliss R, Eilers M, Buchel G. Elife. 2024 Aug 23;13:RP94407. doi: 10.7554/eLife.94407. PubMed |
| Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer. Buglakova E, Ekelof M, Schwaiger-Haber M, Schlicker L, Molenaar MR, Shahraz M, Stuart L, Eisenbarth A, Hilsenstein V, Patti GJ, Schulze A, Snaebjornsson MT, Alexandrov T. Nat Metab. 2024 Sep;6(9):1695-1711. doi: 10.1038/s42255-024-01118-4. Epub 2024 Sep 9. PubMed |
| Targeting aldolase A in hepatocellular carcinoma leads to imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation. Snaebjornsson MT, Poeller P, Komkova D, Rohrig F, Schlicker L, Winkelkotte AM, Chaves-Filho AB, Al-Shami KM, Caballero CD, Koltsaki I, Vogel FCE, Frias-Soler RC, Rudalska R, Schwarz JD, Wolf E, Dauch D, Steuer R, Schulze A. Nat Metab. 2025 Feb;7(2):348-366. doi: 10.1038/s42255-024-01201-w. Epub 2025 Jan 20. PubMed |
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