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The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10.
Lemieux GA, Blumenkron F, Yeung N, Zhou P, Williams J, Grammer AC, Petrovich R, Lipsky PE, Moss ML, Werb Z
J Biol Chem. 2007 May 18. 282(20):14836-44.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
19136CD23b in pIRES2eGFP
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19137mADAM10 E385A in pQCXIP cFLAG
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19138mADAM10 deltaMP in pQCXIP cFLAG
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19140hADAM10 siRNA pSIREN-Retro-Q
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19141mADAM17 in pcDNA3.1
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19144mADAM17deltaMP in pQCXIP cFLAG
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19149mADAM8 deltaMP in pQCXIP cFLAG
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