In vivo RNA editing of point mutations via RNA-guided adenosine deaminases.
Katrekar D, Chen G, Meluzzi D, Ganesh A, Worlikar A, Shih YR, Varghese S, Mali P
Nat Methods. 2019 Mar;16(3):239-242. doi: 10.1038/s41592-019-0323-0. Epub 2019 Feb 8.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 124619 | GluR2_adRNA_(1,20,6)-GFP | Expresses adRNA (1,20,6) targeting the RAB7A transcript along with GFP |
| 124620 | GluR2_adRNA(1,20,6)-ADAR2 | Expresses adRNA (1,20,6) targeting the RAB7A transcript along with the ADAR2 |
| 124621 | GluR2_adRNA(1,20,6)-ADAR2(E488Q) | Expresses adRNA(1,20,6) targeting the RAB7A transcript along with the ADAR2(E488Q) |
| 124622 | GluR2_adRNA(2,100,50)-GFP | Expresses adRNA(2,100,50) targeting the RAB7A transcript along with GFP |
| 124623 | GluR2_adRNA(0,100,50)-GFP | Expresses adRNA(0,100,50) targeting the RAB7A transcript along with GFP |
| 124624 | MS2_adRNA | Expresses MS2_adRNA targeting the RAB7A transcript along with GFP |
| 124625 | MS2_adRNA-MCP_ADAR1 DD_NLS | Expresses MS2_adRNA targeting the RAB7A transcript along with the MCP_ADAR1 DD_NLS |
| 124626 | MS2_adRNA-MCP_ADAR1 DD (E1008Q)_NLS | Expresses MS2_adRNA targeting the RAB7A transcript along with the MCP_ADAR1 DD(E1008Q)_NLS |
| 124630 | MS2_adRNA-MCP_ADAR1 DD_NES | Expresses MS2_adRNA targeting the RAB7A transcript along with MCP_ADAR1 DD_NES |
| 124703 | MS2_adRNA-MCP_ADAR1 DD (E1008Q)_NES | Expresses MS2_adRNA targeting the RAB7A locus along with MCP_ADAR1 DD (E1008Q)_NES |
| 124704 | MS2_adRNA-MCP_ADAR2 DD_NLS | Expresses MS2_adRNA targeting the RAB7A transcript along with the MCP_ADAR2 DD_NLS |
| 124705 | MS2_adRNA-MCP_ADAR2 DD (E488Q)_NLS | Expresses MS2_adRNA targeting the RAB7A transcript along with the MCP_ADAR2 DD(E488Q)_NLS |
| 124706 | MS2_adRNA-MCP_ADAR2 DD_NES | Expresses MS2_adRNA targeting the RAB7A transcript along with the MCP_ADAR2 DD_NES |
| 124707 | MS2_adRNA-MCP_ADAR2 DD (E488Q)_NES | Expresses MS2_adRNA targeting the RAB7A transcript along with the MCP_ADAR2 DD(E488Q)_NES |