Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome.
Parrish PCR, Thomas JD, Gabel AM, Kamlapurkar S, Bradley RK, Berger AH
Cell Rep. 2021 Aug 31;36(9):109597. doi: 10.1016/j.celrep.2021.109597.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 171172 | Human Paralog Knockout Library (pgPEN) | Induces knockouts of paralogous gene pairs. Plasmids express a pair of guide RNAs targeting either individual genes or a pair of paralogs. |