Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia.
    
      Aoki K, Hyuga M, Tarumoto Y, Nishibuchi G, Ueda A, Ochi Y, Sugino S, Mikami T, Kobushi H, Kato I, Akahane K, Inukai T, Takaori-Kondo A, Takita J, Ogawa S, Yusa K
    
    
      Blood. 2023 Nov 3:blood.2023020857. doi: 10.1182/blood.2023020857.
    
    
      
        
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Plasmids from Article
| ID | Plasmid | Purpose | 
|---|---|---|
| 200100 | pKLV2-EF1a-Cas9GFP-W | Lentiviral vector expressing Cas9 fused with GFP at the C-terminus | 
| 200101 | pKLV-EF1a-mCherryLuciferase-W | Lentiviral vector expressing mCherry fused with Luciferase at the C-terminus | 
| 200102 | pKLV-EF1a-mCherryCXCR4-W | Lentiviral vector expressing mCherry fused with CXCR4 cDNA at the C-terminus | 
| 200459 | pKLV2-U6gRNA5(AAVS1)-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human AAVS1 | 
| 200460 | pKLV2-U6gRNA5(CXCR4(12))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4 | 
| 200461 | pKLV2-U6gRNA5(CXCR4(16))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4 | 
| 200462 | pKLV2-U6gRNA5(SMARCA4(15))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human SMARCA4 | 
| 200464 | pKLV2-U6gRNA5(SMARCA4(43))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human SMARCA4 | 
| 200465 | pKLV2-U6gRNA5(SMARCA2(46))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human SMARCA2 | 
| 200467 | pKLV2-U6gRNA5(ARID1A(42))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human ARID1A | 
| 200468 | pKLV2-U6gRNA5(ARID1A(44))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human ARID1A | 
| 200469 | pKLV2-U6gRNA5(ARID1B(21))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human ARID1B | 
| 200470 | pKLV2-U6gRNA5(ARID1B(23))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human ARID1B | 
| 200471 | pKLV2-U6gRNA5(ARID2(13))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human ARID2 | 
| 200472 | pKLV2-U6gRNA5(ARID2(14))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human ARID2 | 
| 200473 | pKLV2-U6gRNA5(BRD9(13))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BRD9 | 
| 200474 | pKLV2-U6gRNA5(BRD9(91))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BRD9 | 
| 200475 | pKLV2-U6gRNA5(GFP)-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting GFP | 
| 200476 | pKLV2-U6gRNA5(CXCR4-SE(95))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-SE | 
| 200477 | pKLV2-U6gRNA5(CXCR4-SE(96))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-SE | 
| 200478 | pKLV2-U6gRNA5(CXCR4-E1(15))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-E1 | 
| 200479 | pKLV2-U6gRNA5(CXCR4-E1(16))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-E1 | 
| 200480 | pKLV2-U6gRNA5(CXCR4-E2(37))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-E2 | 
| 200481 | pKLV2-U6gRNA5(CXCR4-E2(38))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-E2 | 
| 200482 | pKLV2-U6gRNA5(CXCR4-E3(45))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-E3 | 
| 200483 | pKLV2-U6gRNA5(CXCR4-E3(48))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-E3 | 
| 200484 | pKLV2-U6gRNA5(CXCR4-E4(56))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-E4 | 
| 200485 | pKLV2-U6gRNA5(CXCR4-E4(59))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CXCR4-E4 | 
| 200486 | pKLV2-U6gRNA5(CDK6-E1(1))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CDK6-E1 | 
| 200487 | pKLV2-U6gRNA5(CDK6-E1(6))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CDK6-E1 | 
| 200488 | pKLV2-U6gRNA5(CDK6-E2(12))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CDK6-E2 | 
| 200489 | pKLV2-U6gRNA5(CDK6-E2(15))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human CDK6-E2 | 
| 200490 | pKLV2-U6gRNA5(RIC8A(15))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human RIC8A | 
| 200491 | pKLV2-U6gRNA5(RIC8A(16))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human RIC8A | 
| 200492 | pKLV2-U6gRNA5(RHOA(12))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human RHOA | 
| 200493 | pKLV2-U6gRNA5(RHOA(15))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human RHOA | 
| 200494 | pKLV2-U6gRNA5(NDUFA1(11))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human NDUFA1 | 
| 200495 | pKLV2-U6gRNA5(NDUFA1(12))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human NDUFA1 | 
| 200496 | pKLV2-U6gRNA5(MRPL21(14))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human MRPL21 | 
| 200497 | pKLV2-U6gRNA5(MRPL21(16))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human MRPL21 | 
| 200498 | pKLV2-U6gRNA5(MRPS26(12))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human MRPS26 | 
| 200499 | pKLV2-U6gRNA5(MRPS26(15))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human MRPS26 | 
| 200500 | pKLV2-U6gRNA5(RUNX1(11))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human RUNX1 | 
| 200501 | pKLV2-U6gRNA5(RUNX1(13))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human RUNX1 | 
| 200502 | pKLV2.2-h7SKgRNA5(AAVS1)-hU6gRNA5(BbsI)-PGKpuroBFP-W | Lentiviral vector expressing gRNA targeting human AAVS1 | 
| 200503 | pKLV2.2-h7SKgRNA5(SMARCA4(43))-hU6gRNA5(AAVS1)-PGKpuroBFP-W | Lentiviral vector expressing gRNA targeting human SMARCA4 and AAVS1 | 
| 200504 | pKLV2.2-h7SKgRNA5(SMARCA4(43))-hU6gRNA5(SMARCA2(46))-PGKpuroBFP-W | Lentiviral vector expressing gRNA targeting human SMARCA4 and SMARCA2 | 
| 200505 | pKLV2.2-h7SKgRNA5(SMARCA4(43))-hU6gRNA5(SMARCA2(47))-PGKpuroBFP-W | Lentiviral vector expressing gRNA targeting human SMARCA4 and SMARCA2 | 
| 200506 | pKLV2.2-h7SKgRNA5(ARID1A(44))-hU6gRNA5(AAVS1)-PGKpuroBFP-W | Lentiviral vector expressing gRNA targeting human ARID1A and AAVS1 | 
| 200507 | pKLV2.2-h7SKgRNA5(ARID1A(44))-hU6gRNA5(ARID1B(21))-PGKpuroBFP-W | Lentiviral vector expressing gRNA targeting human ARID1A and ARID1B | 
| 200508 | pKLV2.2-h7SKgRNA5(ARID1A(44))-hU6gRNA5(ARID1B(23))-PGKpuroBFP-W | Lentiviral vector expressing gRNA targeting human ARID1A and ARID1B | 
| 200510 | pKLV2-U6gRNA5(SMARCA2(47))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human SMARCA2 | 
| 208545 | pKLV2-U6gRNA5(TAL1(11))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human TAL1 | 
| 208546 | pKLV2-U6gRNA5(TAL1(12))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human TAL1 | 
| 208547 | pKLV2-U6gRNA5(GATA3(12))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human GATA3 | 
| 208548 | pKLV2-U6gRNA5(GATA3(13))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human GATA3 | 
| 208549 | pKLV2-U6gRNA5(ETS1(11))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human ETS1 | 
| 208550 | pKLV2-U6gRNA5(ETS1(12))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human ETS1 | 
| 208551 | pKLV2-U6gRNA5(RUNX3(12))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human RUNX3 | 
| 208552 | pKLV2-U6gRNA5(RUNX3(13))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human RUNX3 | 
| 208554 | pKLV2-U6gRNA5(BCL11B-E1(14))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BCL11B-E1 | 
| 208555 | pKLV2-U6gRNA5(BCL11B-E2(24))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BCL11B-E2 | 
| 208556 | pKLV2-U6gRNA5(BCL11B-E2(25))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BCL11B-E2 | 
| 208557 | pKLV2-U6gRNA5(BCL11B-E3(32))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BCL11B-E3 | 
| 208558 | pKLV2-U6gRNA5(BCL11B-E3(34))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BCL11B-E3 | 
| 208559 | pKLV2-U6gRNA5(BCL11B-E4(42))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BCL11B-E4 | 
| 208560 | pKLV2-U6gRNA5(BCL11B-E4(44))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BCL11B-E4 | 
| 208569 | pKLV2.2-h7SKgRNA5(RUNX1(13))-hU6gRNA5(RUNX3(12))-PGKpuroBFP-W | Lentiviral vector expressing gRNA targeting human RUNX1 and RUNX3 | 
| 208570 | pKLV2.2-h7SKgRNA5(RUNX1(13))-hU6gRNA5(RUNX3(13))-PGKpuroBFP-W | Lentiviral vector expressing gRNA targeting human RUNX1 and RUNX3 | 
| 208756 | pKLV-EF1a-BFPCDK6-W | Lentiviral vector expressing BFP fused with CDK6 cDNA | 
| 208757 | pKLV-EF1a-BFP-W | Lentiviral vector expressing BFP | 
| 208758 | pKLV-EF1a-mCherryBCL11B-W | Lentiviral vector expressing mCherry fused with BCL11B cDNA | 
| 210612 | pKLV2-U6gRNA5(Control(1))-PGKpuro2AmCherry-W | Lentiviral vector expressing gRNA targeting a control region at the CXCR4 locus | 
| 210613 | pKLV2-U6gRNA5(Control(2))-PGKpuro2AmCherry-W | Lentiviral vector expressing gRNA targeting a control region at the CXCR4 locus | 
| 210614 | pKLV2-U6gRNA5(CXCR4-E4(56))-PGKpuro2AmCherry-W | Lentiviral vector expressing gRNA targeting human CXCR4-E4 | 
| 210615 | pKLV2-U6gRNA5(CXCR4-E4(59))-PGKpuro2AmCherry-W | Lentiviral vector expressing gRNA targeting human CXCR4-E4 | 
| 212116 | pKLV2-U6gRNA5(BCL11B-E1(13))-PGKpuro2ABFP-W | Lentiviral vector expressing gRNA targeting human BCL11B-E1 |