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Prime editing of human hematopoietic stem cells for correction of GATA2 deficiency.

Wolff JH, Skov TW, Dorset SR, Sjelborg J, Ravendran S, Revenfeld ALS, Haslund D, Moller AM, Holm M, Thomsen MK, Mogensen TH, Moller BK, Bak RO, Mikkelsen JG
Sci Transl Med. 2026 Sep 30;18(869):eaec7031. doi: 10.1126/scitranslmed.aec7031. Epub 2026 Sep 30. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
241027pT7-PEmax-pA.v3Plasmid for generating template for in vitro transcription of PEmax with a 127 nt pA-tail
241028pT7-PE7-pA.v3Plasmid for generating template for in vitro transcription of PE7 with a 120 nt pA-tail
241029pT7-SpRY-PE7-pA.v3Plasmid for generating template for in vitro transcription of SpRY-PE7 with a 120 nt pA-tail

Antibodies from Article