Epigenome editing of human hematopoietic stem cells enables sustained and reversible thrombosis prevention
Ye T, Xu W, Barrachina MN, Lyu P, Antoszewski M, della Volpe L, Guo C, Lee AJ, Theardy MS, Shelton SD, Wahlster L, Caulier A, Messa L, Poeschla M, Agarwal G, Mitra R, Schmaier AA, Weissman JS, Machlus KR, Sankaran VG
bioRxiv 2026.03.27.714536; doi: 10.64898/2026.03.27.714536
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 258404 | IVT-CRISPRi | Template for in vitro transcription of CRISPRi |
| 258405 | IVT-CRISPRoff | Template for in vitro transcription of CRISPRoff |
| 258406 | IVT-CHARM | Template for in vitro transcription of CHARM |
| 258407 | IVT-CHARM- | Template for in vitro transcription of CHARM without the KRAB domain |
| 258408 | IVT-TET-dCas9 | Template for in vitro transcription of TET-dCas9 |