We narrowed to 16,011 results for: grn

1. pAAV-Tnnt2-Cre-U6-Lmna-sgRNA

   Plasmid

   #206178

   Purpose

   Expresses Cre recombinase specifically in cardiomyocytes and uses U6 promoter to express sgRNAs targeting murine Lmna exon 10

   Depositor

   Yuxuan Guo

   Article

   Sun et al JACC Basic Transl Sci. 2024 Aug 21;9(11)

   Insert

   Cre
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   cTnT

   Available Since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. Tol2-U6.3-sgRNA-empty-GFP

   Plasmid

   #221843

   Purpose

   empty vector to clone custom sgRNA into BsaI sites to express sgRNA from chick U6.3 promoter expresses GFP reporter from GAGC promoter

   Depositor

   Stephen Terry

   Article

   O’Sullivan et al bioRxiv 2024.03.04.583298

   Insert

   EGFP
   

   Use

   CRISPR; Tol2 transposon optimised for chick expre…

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CAGC

   Available Since

   July 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. Tol2-U6.3-sgRNA-DNM1L -GFP

   Plasmid

   #221845

   Purpose

   Tol2 transposon expressing sgRNA targeting chick DNM1L from chick U6.3 promoter expresses GFP reporter from GAGC promoter

   Depositor

   Stephen Terry

   Article

   O’Sullivan et al bioRxiv 2024.03.04.583298

   Inserts

   EGFP
   DNM1L sgRNA-gTGTTTTCCGACCATCCTCTG
   

   Use

   CRISPR; Tol2 transposon optimised for chick expre…

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CAGC and U6.3 chick

   Available Since

   July 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. Tol2-U6.3-sgRNA-MFN1-GFP

   Plasmid

   #221846

   Purpose

   Tol2 transposon expressing sgRNA targeting chick MFN1 from chick U6.3 promoter expresses GFP reporter from GAGC promote

   Depositor

   Stephen Terry

   Article

   O’Sullivan et al bioRxiv 2024.03.04.583298

   Inserts

   EGFP
   MFN1 sgRNA-GAGAAGAAGAGCGTCAAGGT
   

   Use

   CRISPR; Tol2 transposon optimised for chick expre…

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CAGC and U6.3 chick

   Available Since

   July 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. SL3-MS2-gRNA GG backbone (MOBE3-4)

   Plasmid

   #219949

   Purpose

   Golden gate backbone for mammalian expression of Sp-gRNA with SL3-MS2

   Depositor

   Alexis Komor

   Article

   Cowan et al Nat Biotechnol. 2024 May 21. doi: 10.103

   Insert

   gRNA-MS2-SL3 (S. pyogenes Cas9)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   July 30, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pSpCas9-2A-Puro-RAB7A-gRNA2 (PX459)

   Plasmid

   #221552

   Purpose

   Expresses Cas9 and gRNA for disruption of Rab7A gene in human cells

   Depositor

   Shawn Ferguson

   Article

   Talaia et al bioRxiv [Preprint]. 2023 Dec 17:2023.12.

   Insert

   gRNA targeting human Rab7A (RAB7A Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   July 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pX552-EF1a-DIO-mCherry_Dicer gRNA

   Plasmid

   #215279

   Purpose

   Expresses Dicer gRNA in a Cre dependent mcherry vector

   Depositor

   Bryan Copits

   Article

   Moffa et al eNeuro. 2024 Jul 5;11(7):ENEURO.0438-23.

   Insert

   Dicer control gRNA
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   July 8, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pX552-EF1a-DIO-mCherry_DicerTTT gRNA

   Plasmid

   #215280

   Purpose

   Expresses Dicer Control gRNA in a Cre dependent mcherry vector

   Depositor

   Bryan Copits

   Article

   Moffa et al eNeuro. 2024 Jul 5;11(7):ENEURO.0438-23.

   Insert

   Dicer control gRNA
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   July 8, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pX552-hSyn-DIO-GCaMP8f_Grin1 gRNA

   Plasmid

   #215281

   Purpose

   Expresses Grin 1 gRNA in a Cre dependent GCaMP8f vector

   Depositor

   Bryan Copits

   Article

   Moffa et al eNeuro. 2024 Jul 5;11(7):ENEURO.0438-23.

   Insert

   Grin1 gRNA
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   See Depositor Comments Below

   Promoter

   U6

   Available Since

   July 8, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pX552-hSyn-DIO-GCaMP8f_Grin1TTT gRNA

    Plasmid

    #215282

    Purpose

    Expresses Grin1 Control gRNA in a Cre dependent GCaMP8f vector

    Depositor

    Bryan Copits

    Article

    Moffa et al eNeuro. 2024 Jul 5;11(7):ENEURO.0438-23.

    Insert

    Grin1 control gRNA
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available Since

    July 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pCAG-eSpCas9-2A-GFP-sgRNA-Lig4

    Plasmid

    #220494

    Purpose

    To generate LIG4 KO in human cells. Co-expresses eSpCas9(1.1), GFP and a guide RNA against LIG4 exon 3.

    Depositor

    Sébastien Britton

    Article

    Bossaert et al bioRxiv [Preprint]. 2024 Jan 4:2024.01.0

    Insert

    sgRNA targeting LIG4 exon 3 (LIG4 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available Since

    July 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLV-GG-hUbC-EBPF2-gRNA-FAM13A

    Plasmid

    #185550

    Purpose

    Lentiviral backbone with EBFP2 reporter and gRNA targeting FAM13A

    Depositor

    Andrew Wilson

    Article

    Werder et al Sci Adv. 2022 Jul 15;8(28):eabo6566. doi

    Insert

    FAM13A gRNAs
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    June 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. Lenti-N1303K-ngRNA+14_EF1a-puroR

    Plasmid

    #207359

    Purpose

    Lentiviral transfer plasmid encoding hU6-driven expression of a ngRNA for correction of N1303K-CFTR via prime editing and EF1a-driven puromycin resistance gene.

    Depositor

    Marianne Carlon

    Article

    Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

    Insert

    N1303K-CFTR +14 ngRNA
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. Lenti-L227R-ngRNA+15_EF1a-puroR

    Plasmid

    #207360

    Purpose

    Lentiviral transfer plasmid encoding hU6-driven expression of a ngRNA for correction of L227R-CFTR via prime editing and EF1a-driven puromycin resistance gene.

    Depositor

    Marianne Carlon

    Article

    Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

    Insert

    L227R-CFTR +15 ngRNA
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCF821-recipient_U6-sgRNA-EF1a-mNeonGreen

    Plasmid

    #211651

    Purpose

    U6-sgRNA-EF1a-mNeonGreen

    Depositor

    Christof Fellmann

    Article

    Tan et al Cell Rep. 2023 Nov 28;42(11):113339. doi

    Insert

    Guide RNA recipient vector
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCF820-recipient_U6-sgRNA-EF1a-mCherry2

    Plasmid

    #211647

    Purpose

    U6-sgRNA-EF1a-mCherry2

    Depositor

    Christof Fellmann

    Article

    Tan et al Cell Rep. 2023 Nov 28;42(11):113339. doi

    Insert

    Guide RNA recipient vector
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. Lenti-sgRNA-Cre-GpNLuc-sgmATM

    Plasmid

    #208392

    Purpose

    Lentiviral vector expressing Cas9, GpNLuc, and sgRNA targeting murine ATM gene.

    Depositor

    Gaorav Gupta

    Article

    Cho et al Nature. 2024 Jan 10. doi: 10.1038/s41586

    Insert

    sgATM (Atm Mouse)
    

    Use

    Lentiviral and Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    Available Since

    Jan. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Lenti-sgRNA-Cre-GpNLuc-sgmMRE11

    Plasmid

    #208384

    Purpose

    Lentiviral vector expressing Cas9, GpNLuc, and sgRNA targeting murine MRE11 gene.

    Depositor

    Gaorav Gupta

    Article

    Cho et al Nature. 2024 Jan 10. doi: 10.1038/s41586

    Insert

    sgMRE11 (Mre11a Mouse)
    

    Use

    Lentiviral and Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    Available Since

    Jan. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. Lenti-sgRNA-Cre-GpNLuc-sgmZBP1#3

    Plasmid

    #208389

    Purpose

    Lentiviral vector expressing Cas9, GpNLuc, and sgRNA targeting murine ZBP1#3 gene.

    Depositor

    Gaorav Gupta

    Article

    Cho et al Nature. 2024 Jan 10. doi: 10.1038/s41586

    Insert

    sgZBP1 (Zbp1 Mouse)
    

    Use

    Lentiviral and Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    Available Since

    Jan. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. Lenti-sgRNA-Cre-GpNLuc-sgmMLKL

    Plasmid

    #208391

    Purpose

    Lentiviral vector expressing Cas9, GpNLuc, and sgRNA targeting murine MLKL gene.

    Depositor

    Gaorav Gupta

    Article

    Cho et al Nature. 2024 Jan 10. doi: 10.1038/s41586

    Insert

    sgMLKL (Mlkl Mouse)
    

    Use

    Lentiviral and Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    Available Since

    Jan. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge