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AiP1438 - pAAV-AiE2167m-minBG-SYFP2-WPRE-BGHpA

Plasmid

#214499

Purpose

AiE2167m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Promoter

minBG

Available Since

June 24, 2024

Availability

Academic Institutions and Nonprofits only

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AiP1439 - pAAV-AiE2168m-minBG-SYFP2-WPRE-BGHpA

Plasmid

#214500

Purpose

AiE2168m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Promoter

minBG

Available Since

June 24, 2024

Availability

Academic Institutions and Nonprofits only

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AiP1514 - pAAV-AiE2193m-minBG-SYFP2-WPRE-BGHpA

Plasmid

#214504

Purpose

AiE2193m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Promoter

minBG

Available Since

June 24, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP1272 - pAAV-AiE2088m-minBG-SYFP2-WPRE-BGHpA

Plasmid

#214478

Purpose

AiE2088m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Promoter

minBG

Available Since

June 24, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP1331 - pAAV-AiE2113m-minBG-SYFP2-WPRE-BGHpA

Plasmid

#214482

Purpose

AiE2113m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Promoter

minBG

Available Since

June 24, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP1351 - pAAV-AiE2E122m-minBGpromoter-SYFP2-WPRE3-bGHpA

Plasmid

#208139

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

April 10, 2024

Availability

Academic Institutions and Nonprofits only

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AiP1389 - pAAV-AiE2E160m-minBGpromoter-SYFP2-WPRE3-bGHpA

Plasmid

#208140

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1389 - pAAV-AiE2160m-minBG-SYFP2-WPRE-BGHpA

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP1457 - pAAV-AiE2E121m-minBGpromoter-SYFP2-WPRE3-bGHpA

Plasmid

#208138

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1457 - pAAV-AiE2121m-minBG-SYFP2-WPRE-BGHpA

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP1349 - pAAV-AiE2E120m-minBGpromoter-SYFP2-WPRE3-bGHpA

Plasmid

#208137

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1349 - pAAV-AiE2120m-minBG-SYFP2-WPRE-BGHpA

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP1346 - pAAV-AiE2E117m-minBGpromoter-SYFP2-WPRE3-bGHpA

Plasmid

#208135

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1346 - pAAV-AiE2117m-minBG-SYFP2-WPRE-BGHpA

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-EF1a-IgK-HT9-PDGFR-IRES-oScarlet-WPRE

Plasmid

#252087

Purpose

Expresses membrane bound halotag in mammalian cells with oScarlet fluorophore

Depositor

Karl Deisseroth

Article

Zhao et al ChemRxiv. 2024

Insert

IgK-HT9-PDGFR-IRES-oScarlet

Use

AAV

Expression

Mammalian

Promoter

EF1a

Available Since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-EF1a-Igk-HT9-PDGFR-IRES-sfGFP-WPRE

Plasmid

#252088

Purpose

Expresses membrane bound halotag in mammalian cells with GFP fluorophore

Depositor

Karl Deisseroth

Article

Zhao et al ChemRxiv. 2024

Insert

Igk-HT9-PDGFR-IRES-sfGFP

Use

AAV

Expression

Mammalian

Promoter

EF1a

Available Since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-EF1a-Igk-HT9-PDGFR-IRES-BFP-WPRE

Plasmid

#252086

Purpose

Expresses membrane bound halotag in mammalian cells with BFP fluorophore

Depositor

Karl Deisseroth

Article

Zhao et al ChemRxiv. 2024

Insert

Igk-HT9-PDGFR-IRES-BFP

Use

AAV

Expression

Mammalian

Promoter

EF1a

Available Since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-GRAB_CRF0.5

Plasmid

#208657

Purpose

Expresses the genetically-encoded fluorescent corticotropin-releasing factor (CRF) sensor GRAB_CRF0.5 in neurons

Depositor

Yulong Li

Article

Wang et al Science. 2023 Nov 17;382(6672):eabq8173.

Insert

GPCR activation based corticotropin-releasing factor (CRF) sensor GRAB_CRF0.5

Use

AAV

Promoter

hSyn

Available Since

Oct. 23, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV_Donor/Reporter-COL4A3

Plasmid

#130279

Purpose

COL4A3 mutation-specific sgRNA under the control of U6 promoter; mCherry-sgRNA target-(out of frame)EGFP expression cassette; COL4A3 donor template

Depositor

Silvestro Conticello

Article

Daga et al Eur J Hum Genet. 2019 Nov 21. pii: 10.10

Insert

mCherry-eGFP

Use

AAV

Promoter

CMV

Available Since

Dec. 15, 2020

Availability

Academic Institutions and Nonprofits only

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pAAV-CMV-PDGFRb559-562del-HA

Plasmid

#204351

Purpose

Expresses a mutant PDGFRb gene (559-562 deletion). Used for DNA delivery using Adeno-associated Virus.

Depositor

Hirofumi Nakatomi

Article

Shima et al Sci Transl Med. 2023 Jun 14;15(700):eabq

Insert

Platelet derived growth factor receptor beta (PDGFRB) (PDGFRB Human)

Use

AAV

Tags

HA

Mutation

559-562 deletion

Available Since

Sept. 18, 2023

Availability

Academic Institutions and Nonprofits only

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pKT07_AAV-hU6-AsDR-crTSG1-EFS-Cre-T2A-hNGFR

Plasmid

#256630

Purpose

AAV vector for delivery of AsCas12a crTSG1 guide array and expressing Cre using EFS promoter

Depositor

Sidi Chen

Article

Tang et al Nat Biomed Eng. 2025 Aug;9(8):1290-1308.

Insert

crTrp53, crPten, crApc, crRb1

Use

AAV

Promoter

humanU6, EFS-NS

Available Since

June 9, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-CMV-DIO-SaCas9-U6-sgDagla

Plasmid

#239421

Purpose

Knockdown expression of Dagla

Depositor

Huaibin Cai

Article

Liu et al Nat Commun. 2022 Jun 17;13(1):3490. doi:

Insert

diacylglycerol lipase, alpha (Dagla Mouse)

Use

AAV, CRISPR, and Mouse Targeting

Promoter

CMV

Available Since

Jan. 6, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-C-intein-C-spC9-H840A-N863A-2xNLS-hGH

Plasmid

#112211

Purpose

Targeted DNA methylation

Depositor

Xingxu Huang

Article

Lu et al Cell Death Dis. 2020 Feb 3;11(2):85. doi

Insert

C-terminus of dCas9

Use

AAV

Mutation

D10A

Available Since

Oct. 30, 2020

Availability

Academic Institutions and Nonprofits only

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pAAV-Ef1a-DIO-Pgc-1alpha-EYFP

Plasmid

#241793

Purpose

Expression vector for mouse Pgc-1alpha with EYFP

Depositor

Mary Kay Lobo

Article

Chandra et al Biol Psychiatry. 2017 Apr 1;81(7):564-57

Insert

PGC-1alpha (Ppargc1a Mouse)

Use

AAV

Tags

EYFP

Promoter

Ef1a

Available Since

Nov. 12, 2025

Availability

Academic Institutions and Nonprofits only

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