We narrowed to 5,539 results for: KRAS

1. pWZL-hygro-FAKS732A/S910A

   Plasmid

   #221642

   Purpose

   This retroviral plasmid expresses a double-mutated cDNA (dominant negative: S732A/S910A) of human PTK2

   Depositor

   Georgia Konstantinidou

   Article

   Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

   Insert

   PTK2 (S732A/S910A) (PTK2 Human)
   

   Use

   Retroviral

   Tags

   No

   Expression

   Mammalian

   Mutation

   FAK double mutation S732A/S910A (dominant negativ…

   Available Since

   Sept. 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pWZL-hygro-FAKR177/178A

   Plasmid

   #216543

   Purpose

   This retroviral plasmid expresses a mutated cDNA (dominant negative: R177/178A) of human PTK2

   Depositor

   Georgia Konstantinidou

   Article

   Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

   Insert

   PTK2 (R177/178A) (PTK2 Human)
   

   Use

   Retroviral

   Tags

   No

   Expression

   Mammalian

   Mutation

   FAK dominant negative mutation R177/178A

   Available Since

   Sept. 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pCAGGS_m-AKAR5

   Plasmid

   #114139

   Purpose

   Mammalian expression of the AKAR5 sensor C-terminally fused to the C-terminus of KRas (membrane targeting) for detecting PKA activity using two-photon fluorescence lifetime imaging microscopy (2pFLIM)

   Depositor

   Haining Zhong

   Article

   Tillo et al Cell Rep. 2017 Apr 18;19(3):617-629. doi

   Insert

   AKAR5 C-terminally tagged by KRas C tail
   

   Expression

   Mammalian

   Available Since

   Oct. 4, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. plko-tet-on puromycin-shMTH1

   Plasmid

   #110918

   Purpose

   To knock down MTH1 (Mut T Homolog 1) after addition of doxycline

   Depositor

   Priyamvada Rai

   Article

   Patel et al Oncogene. 2015 May 14;34(20):2586-96. do

   Insert

   MTH1 (NUDT1 Human)
   

   Use

   Lentiviral

   Available Since

   June 14, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. 6691 Bicistronic_ires_puro

   Plasmid

   #64335

   Purpose

   This a retroviral expression plasmid with a minimal polylinker followed by IRES and puro resistance gene

   Depositor

   Georgios Stathopoulos

   Article

   Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

   Type

   Empty backbone

   Use

   Retroviral

   Available Since

   July 3, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. R711-X04-566: His6-MBP-tev-Hs.NF1iso2 (1198-1530)

   Plasmid

   #159579

   Purpose

   E. coli protein expression of His6-MBP-tev-Hs.NF1 DEF (1198-1530)

   Depositor

   Dominic Esposito

   Article

   Yan et al Cell Rep. 2020 Jul 21;32(3):107909. doi:

   Insert

   His6-MBP-tev-Hs.NF1 DEF (1198-1530) (NF1 Human)
   

   Tags

   His6-MBP-tev

   Expression

   Bacterial

   Available Since

   Sept. 29, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. R711-X12-566: His6-MBP-tev-Hs.NF1iso2 (1203-1530)

   Plasmid

   #159580

   Purpose

   E. coli protein expression of His6-MBP-tev-Hs.NF1iso2 (1203-1530)

   Depositor

   Dominic Esposito

   Article

   Yan et al Cell Rep. 2020 Jul 21;32(3):107909. doi:

   Insert

   His6-MBP-tev-Hs.NF1iso2 (1203-1530) (NF1 Human)
   

   Tags

   His6-MBP-tev

   Expression

   Bacterial

   Available Since

   Sept. 28, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. TRMPVneo.Yap.3093

   Plasmid

   #59915

   Purpose

   Tet on shRNA for conditional Yap1 knockdown

   Depositor

   Tyler Jacks

   Article

   Shao et al Cell. 2014 Jul 3;158(1):171-84. doi: 10.

   Insert

   Yap1 (Yap1 Mouse)
   

   Use

   Retroviral

   Available Since

   Sept. 11, 2014

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pUG2K

   Plasmid

   #35493

   Depositor

   Ramesh Shivdasani

   Article

   Horst et al Cancer Res. 2012 Feb 8.

   Insert

   KRAS(G12V) (KRAS Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   G12V

   Promoter

   Ubiquitin C

   Available Since

   May 8, 2012

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pRL K-ras 3'UTR mutant

    Plasmid

    #14805

    Depositor

    Tyler Jacks

    Article

    Kumar et al Nat Genet. 2007 May;39(5):673-7. doi: 10

    Insert

    K-ras 3'UTR (Kras Mouse)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    let-7 miRNA binding site mutations

    Available Since

    April 6, 2007

    Availability

    Academic Institutions and Nonprofits only

11. 7432 Bicistronic_GFP_ires_puro

    Plasmid

    #64336

    Purpose

    This a retroviral expression plasmid expressing GFP along with puro resistance gene

    Depositor

    Georgios Stathopoulos

    Article

    Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

    Insert

    GFP
    

    Use

    Retroviral

    Tags

    GFP

    Available Since

    July 3, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. 7749 Bicistronic_ires_hygro

    Plasmid

    #64374

    Purpose

    This a retroviral expression plasmid with a minimal polylinker followed by IRES and hygro resistance gene

    Depositor

    Georgios Stathopoulos

    Article

    Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

    Type

    Empty backbone

    Use

    Retroviral

    Available Since

    July 3, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. 8200 Bicistronic_GFP_ires_hygro

    Plasmid

    #64375

    Purpose

    This a retroviral expression plasmid expressing GFP along with hygro resistance gene

    Depositor

    Georgios Stathopoulos

    Article

    Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

    Insert

    EGFP
    

    Use

    Retroviral

    Tags

    EGFP

    Available Since

    July 3, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pJV126

    Plasmid

    #124250

    Purpose

    In vitro transcription plasmid for T7 transcription of wildtype Her2 sequence targeted to the endosome. Linearize with SapI.

    Depositor

    Stanley Riddell

    Article

    Veatch et al Cancer Immunol Res. 2019 Jun;7(6):910-92

    Insert

    Minigene containing Her2 sequences fused to endosomal targeting sequence of class I MHC
    

    Use

    In vitro transcription template

    Promoter

    T7

    Available Since

    May 3, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pJV127

    Plasmid

    #124251

    Purpose

    In vitro transcription plasmid for T7 transcription of Her2 ITD sequence targeted to the endosome. Linearize with SapI.

    Depositor

    Stanley Riddell

    Article

    Veatch et al Cancer Immunol Res. 2019 Jun;7(6):910-92

    Insert

    Minigene containing Her2 sequences fused to endosomal targeting sequence of class I MHC
    

    Use

    In vitro transcription template

    Promoter

    T7

    Available Since

    May 3, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. Mouse sphingolipid metabolism knockout library

    Pooled Library

    #206249

    Purpose

    The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

17. Mouse lipid metabolism knockout library

    Pooled Library

    #206248

    Purpose

    The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

18. GPS-MYC

    Plasmid

    #160130

    Purpose

    A reporter that monitors MYC protein expression.

    Depositor

    Channing Der

    Article

    Blake et al Sci Signal. 2019 Jul 16;12(590). pii: 12

    Insert

    MYC (MYC Human)
    

    Use

    Lentiviral

    Tags

    EGFP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 28, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. Lenti-sgNT.2#2/Cre

    Plasmid

    #173661

    Purpose

    Expresses a NT.2-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    Non-targeting gRNA
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    May 17, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. R701-X65-527: His6-tev-Hs.CALM1(2-148)

    Plasmid

    #159693

    Purpose

    E. coli protein expression of His6-tev-Hs.CALM1(2-148)

    Depositor

    Dominic Esposito

    Article

    Agamasu et al Biophys J. 2019 Mar 19;116(6):1049-1063.

    Insert

    His6-tev-Hs.CALM1(2-148) (CALM1 Human)
    

    Tags

    His6-tev

    Expression

    Bacterial

    Available Since

    Oct. 5, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge