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SFFV-MYCL-dTomato

Plasmid

#242694

Purpose

Validation of factors that enhance cDC1 reprogramming fidelity. Lentiviral expresison of MYCL with dTomato.

Depositor

Filipe Pereira

Article

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

MYCL (MYCL Human)

Use

Lentiviral

Promoter

SFFV (spleen focus-forming virus) promoter

Available Since

July 10, 2026

Availability

Academic Institutions and Nonprofits only

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SFFV-GATA2-dTomato

Plasmid

#242696

Purpose

Validation of factors that enhance cDC1 reprogramming fidelity. Lentiviral expresison of GATA2 with dTomato.

Depositor

Filipe Pereira

Article

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

GATA2 (GATA2 Human)

Use

Lentiviral

Promoter

SFFV (spleen focus-forming virus) promoter

Available Since

July 10, 2026

Availability

Academic Institutions and Nonprofits only

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SFFV-NFKBIA-dTomato

Plasmid

#242697

Purpose

Validation of factors for immature cDC1 reprogramming fidelity. Lentiviral expresison of NFKBIA with dTomato.

Depositor

Filipe Pereira

Article

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

NFKBIA (NFKBIA Human)

Use

Lentiviral

Promoter

SFFV (spleen focus-forming virus) promoter

Available Since

July 10, 2026

Availability

Academic Institutions and Nonprofits only

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SFFV-STAT3-dTomato

Plasmid

#242691

Purpose

Validation of factors that enhance cDC1 reprogramming fidelity. Lentiviral expresison of STAT3 with dTomato.

Depositor

Filipe Pereira

Article

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

STAT3 (STAT3 Human)

Use

Lentiviral

Promoter

SFFV (spleen focus-forming virus) promoter

Available Since

July 10, 2026

Availability

Academic Institutions and Nonprofits only

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pUC19_CoV-2_frD2_ΔrE/esxA Δ67 3*

Plasmid

#253180

Purpose

For recombinant virus rescue; encodes fragment D2 of SARS-CoV-2 (nt25422-29867), with deletion of envelope, orf6, orf7a;stop codon at AA213 in orf3a; Mycobacterium tuberculosis esxA replaces envelope

Depositor

Thomas Klimkait

Article

Kipfer et al Elife. 2023 Nov 21;12:RP89035. doi: 10.7

Insert

CoV-2 frD2 with esxA

Expression

Bacterial

Available Since

April 27, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hRAB23-gRNA3

Plasmid

#249236

Purpose

RAB23 CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

RAB23 (RAB23 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hRAB23-gRNA2

Plasmid

#249235

Purpose

RAB23 CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

RAB23 (RAB23 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hRAB23-gRNA1

Plasmid

#249234

Purpose

RAB23 CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

RAB23 (RAB23 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hPTPRF-gRNA3

Plasmid

#249230

Purpose

PTPRF CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

PTPRF (PTPRF Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hPTPRF-gRNA2

Plasmid

#249229

Purpose

PTPRF CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

PTPRF (PTPRF Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hPTPRF-gRNA1

Plasmid

#249228

Purpose

PTPRF CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

PTPRF (PTPRF Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hPTK7-gRNA3

Plasmid

#249209

Purpose

PTK7 CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

PTK7 (PTK7 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hPTK7-gRNA2

Plasmid

#249208

Purpose

PTK7 CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

PTK7 (PTK7 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hPTK7-gRNA1

Plasmid

#249207

Purpose

PTK7 CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

PTK7 (PTK7 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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pCBS-5738

Plasmid

#249324

Purpose

To express the EPEC DarT2(DLAA)-nScCas9(D10A) fusion protein in experiments for Append Editing

Depositor

Chase Beisel

Article

Gupta et al Nat Biotechnol. 2025 Sep 4. doi: 10.1038

Insert

EPEC DarT2(DLAA)-nScCas9(D10A)

Expression

Yeast

Mutation

DarT2(G49D, M86L, R92A, R193A) and nScCas9(D10A)

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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pCBS-5753

Plasmid

#249325

Purpose

To express the EPEC dDarT2(DLAA)-nScCas9(D10A) fusion protein in experiments for Append Editing

Depositor

Chase Beisel

Article

Gupta et al Nat Biotechnol. 2025 Sep 4. doi: 10.1038

Insert

EPEC dDarT2(DLAA)-nScCas9(D10A)

Expression

Yeast

Mutation

DarT2(G49D, M86L, R92A, E,170A, R193A) and nScCas…

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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AAV_CMV-AcrIIA5_cpGR2(GGS5)-N77

Plasmid

#246048

Purpose

Expression of AcrIIA5-cpGR2 hybrid in mammalian cells; insertion before N77; enables chemogenetic control of SauCas9; contains ITRs for AAV packaging with Rep2

Depositor

Dominik Niopek

Article

Brenker et al Nucleic Acids Res. 2025 Jul 19;53(14):gk

Insert

AcrIIA5_cpGR2-N77

Use

AAV, CRISPR, and Synthetic Biology

Expression

Mammalian

Promoter

CMV

Available Since

Dec. 15, 2025

Availability

Academic Institutions and Nonprofits only

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AcrVA1_cpGR2(GGS5)-S103ΔELS_(GGS)2-(GGS)2

Plasmid

#246051

Purpose

Expression of AcrVA1-cpGR2 hybrid in mammalian cells; insertion before S103 with deletion of surrounding amino acids ELS and GGS2 linkers; enables chemogenetic control of MbCas12a

Depositor

Dominik Niopek

Article

Brenker et al Nucleic Acids Res. 2025 Jul 19;53(14):gk

Insert

AcrVA1_cpGR2-S103ΔELS

Use

CRISPR and Synthetic Biology

Expression

Mammalian

Mutation

ΔELS

Available Since

Dec. 15, 2025

Availability

Academic Institutions and Nonprofits only

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CMV_AcrIIA4_cpGR2(GGS5)-ΔN64_Q65_E66

Plasmid

#246052

Purpose

Expression of AcrIIA4-cpGR2 hybrid in mammalian cells after Bubeck et al Nat Methods 2018; enables chemogenetic control of SpyCas9

Depositor

Dominik Niopek

Article

Brenker et al Nucleic Acids Res. 2025 Jul 19;53(14):gk

Insert

AcrIIA4_cpGR2-ΔN64/Q65/E66

Use

CRISPR and Synthetic Biology

Expression

Mammalian

Mutation

ΔN64/Q65/E66

Available Since

Dec. 15, 2025

Availability

Academic Institutions and Nonprofits only

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SFFV-SOX6-Brd 348

Plasmid

#219274

Purpose

Transcription factor SOX6 with a specific barcode assigned.

Depositor

Filipe Pereira

Article

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

SOX6 (SOX6 Human)

Use

Lentiviral

Promoter

The spleen focus-forming virus (SFFV) promoter

Available Since

Oct. 29, 2025

Availability

Academic Institutions and Nonprofits only

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