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CA-0064 CMVTO-SumIL2-noGS-rens-IL2Rb

Plasmid

#231218

Purpose

CageIL-2 (N-term 0 AA)

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

SumIL2-noGS-rens-IL2Rb (IL2 Human)

Expression

Mammalian

Mutation

L80F, R81D, L85V, I86V, I92F

Available since

Jan. 27, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0140 CMVTO-Renin-ECL-CD4-tevs-RXR6.2

Plasmid

#231199

Purpose

ER-retained renin

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

Renin-ECL-CD4-tevs-RXR6.2 (REN Human)

Expression

Mammalian

Available since

Jan. 27, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0234 CMVTO-sumIL2-rensGS.3

Plasmid

#231198

Purpose

CleaveIL-2

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

sumIL2-rensGS.3 (IL2 Human)

Expression

Mammalian

Mutation

L80F, R81D, L85V, I86V, I92F

Available since

Jan. 27, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0165 CMVTO-mono-hIL10 (R5A11M)-rens

Plasmid

#231196

Purpose

CleaveIL-10

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

mono-hIL10 (R5A11M)-rens (IL10 Human)

Expression

Mammalian

Mutation

N36I, N110I, K117N, F129L

Available since

Jan. 27, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0091 CMVTO-mono-hIL10-R5A11M-rens-3GS-IL10Ra

Plasmid

#231191

Purpose

CageIL-10-monomer

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

mono-hIL10-R5A11M-rens-3GS-IL10Ra (IL10 Human)

Expression

Mammalian

Mutation

N36I, N110I, K117N, F129L

Available since

Jan. 27, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0210 CMVTO-hIL2-rens-del.1

Plasmid

#231227

Purpose

CleaveIL-2_loop1_del

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

hIL2-rens-del.1 (IL2 Human)

Expression

Mammalian

Mutation

L80F, R81D, L85V, I86V, I92F

Available since

Jan. 27, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0211 CMVTO-hIL2-rens-del.2

Plasmid

#231228

Purpose

CleaveIL-2_loop3_del

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

hIL2-rens-del.2 (IL2 Human)

Expression

Mammalian

Mutation

L80F, R81D, L85V, I86V, I92F

Available since

Jan. 27, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0194 CMVTO-secNLuc-rens-mem

Plasmid

#231211

Purpose

Membrane-bound nanoluciferase

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

secNLuc-rens-mem

Expression

Mammalian

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CMVTO-SEAP

Plasmid

#231212

Purpose

Secreted Embryonic Alkaline Phosphatase

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

SEAP

Expression

Mammalian

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0201 CMVTO-hIL6-rens.1

Plasmid

#231197

Purpose

CleaveIL-6

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

hIL6-rens.1 (IL6 Human)

Expression

Mammalian

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0151 CMVTO-Renin(H2M)-ECL

Plasmid

#231201

Purpose

Membrane-bound human-to-mouse (H2M) renin

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

Renin(H2M)-ECL (REN Human)

Expression

Mammalian

Mutation

L147I, R148H, I203V, L290V

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0212 CMVTO-hIL2-rens-del.3

Plasmid

#231229

Purpose

CleaveIL-2_loop2_del

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

hIL2-rens-del.3 (IL2 Human)

Expression

Mammalian

Mutation

L80F, R81D, L85V, I86V, I92F

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0033 CMVTO-hIL6

Plasmid

#231192

Purpose

Human IL-6

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

Human IL-6 (IL6 Human)

Expression

Mammalian

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0202 CMVTO-hIL6-rens.1_Del

Plasmid

#231225

Purpose

CleaveIL-6_Del

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

hIL6-rens.1_Del (IL6 Human)

Expression

Mammalian

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0045 CMVTO-mono-hIL10 (R5A11M)

Plasmid

#231190

Purpose

Mutant human IL-10 monomer

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

mono-hIL10 (R5A11M) (IL10 Human)

Expression

Mammalian

Mutation

N36I, N110I, K117N, F129L

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0058 CMVTO-SumIL2-rens-3GS-IL2Rb

Plasmid

#231223

Purpose

CageIL-2 (C-term 15 AA)

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

SumIL2-rens-3GS-IL2Rb (IL2 Human)

Expression

Mammalian

Mutation

L80F, R81D, L85V, I86V, I92F

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0063 CMVTO-SumIL2-5GS-rens-IL2Rb

Plasmid

#231221

Purpose

CageIL-2 (N-term 25 AA)

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

SumIL2-5GS-rens-IL2Rb (IL2 Human)

Expression

Mammalian

Mutation

L80F, R81D, L85V, I86V, I92F

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0061 CMVTO-SumIL2-2GS-rens-IL2Rb

Plasmid

#231219

Purpose

CageIL-2 (N-term 10 AA)

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

SumIL2-2GS-rens-IL2Rb (IL2 Human)

Expression

Mammalian

Mutation

L80F, R81D, L85V, I86V, I92F

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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CMVTO-hIL2 (AV)

Plasmid

#231226

Purpose

hIL2

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

hIL2 (IL2 Human)

Expression

Mammalian

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pdnCas3-APOBEC1

Plasmid

#229537

Purpose

pMV_hyg encoding dnCas3(H74A+D75A)-rAPOBEC1 fusion construct and crRNA expression cassette. Respective crRNA spacer can be introduced via BsmBI restriction cloning

Depositor

Kevin Verstrepen

Publication

Zimmermann et al Nat Commun. 2023 Jun 9;14(1):3389. doi:

Inserts

rAPOBEC1
dnCas3
Uracil glycosylase inhibitor

Tags

XTEN

Expression

Bacterial and Yeast

Mutation

codon optimized for S.cerevisiae and codon optimi…

Available since

Jan. 23, 2025

Availability

Academic Institutions and Nonprofits only

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