We narrowed to 7,218 results for: aav

1. AAV-U6-sgMap3K13(1)-U6-sgMap3K12(1)-hSyn1-mCherry

   Plasmid

   #208837

   Purpose

   Knockout of Map3K12 (DLK) and Map3K13 (LZK) using tandem sgRNAs, expresses mCherry under the hSyn1 promoter

   Depositor

   Ben Emery

   Article

   Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

   Insert

   mCherry
   

   Use

   AAV and CRISPR

   Expression

   Bacterial and Mammalian

   Promoter

   hSyn1

   Available Since

   Oct. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. AAVS1_dCas9-XTEN-KRAB-p2A-mCherry

   Plasmid

   #222107

   Purpose

   Donor vector for CRISPRi integration at AAVS1 with an mCherry fluorophore

   Depositor

   Jonathan Weissman

   Article

   She et al Cell. 2023 Jul 6;186(14):2977-2994.e23.

   Insert

   CRISPRi-kox1(KRAB) (cas9 S. pyogenes, Human)
   

   Use

   AAV and CRISPR

   Tags

   HA and P2A-mCherry

   Expression

   Mammalian

   Mutation

   D10A, H840A

   Available Since

   Oct. 10, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. AAVS1_dCas9-XTEN-KRAB-p2A-GFP

   Plasmid

   #222108

   Purpose

   Donor vector for CRISPRi integration at AAVS1 with a GFP fluorophore

   Depositor

   Jonathan Weissman

   Article

   She et al Cell. 2023 Jul 6;186(14):2977-2994.e23.

   Insert

   CRISPRi-kox1(KRAB) (cas9 S. pyogenes, Human)
   

   Use

   AAV and CRISPR

   Tags

   HA and P2A-GFP

   Expression

   Mammalian

   Mutation

   D10A, H840A

   Available Since

   Oct. 4, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-U6-sgPet-1-hSyn-mCherry-KASH

   Plasmid

   #223227

   Purpose

   guideRNA targeting the mouse Pet-1 (Fev)

   Depositor

   Kyungjin Kim

   Article

   Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

   Insert

   Fev (Fev Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Sept. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pBK1302-AAV-EFSNC-dCjCas9-KRAB

   Plasmid

   #223147

   Purpose

   Expression of KRAB with dCjCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   KRAB
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-Tnnt2-Cre-U6-Lmna-sgRNA

   Plasmid

   #206178

   Purpose

   Expresses Cre recombinase specifically in cardiomyocytes and uses U6 promoter to express sgRNAs targeting murine Lmna exon 10

   Depositor

   Yuxuan Guo

   Article

   Sun et al JACC Basic Transl Sci. 2024 Aug 21;9(11)

   Insert

   Cre
   

   Use

   AAV

   Promoter

   cTnT

   Available Since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-Loxp-CMV-Loxp-GFP-LA

   Plasmid

   #206199

   Purpose

   Expresses GFP-lamin-A only in non-myocyte when delivered into mice carrying a cardiomyocyte-specific Myh6-Cre transgene

   Depositor

   Yuxuan Guo

   Article

   Sun et al JACC Basic Transl Sci. 2024 Aug 21;9(11)

   Insert

   Lmna (LMNA Human)
   

   Use

   AAV

   Tags

   GFP

   Promoter

   CMV

   Available Since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pBK1312-AAV-EFSNC-dSaCas9-KRAB

   Plasmid

   #223157

   Purpose

   Expression of KRAB with dSaCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   KRAB
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   Aug. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV hSyn RSET-T-GECO1.WPRE

   Plasmid

   #211902

   Purpose

   Expresses T-GECO1 in mammalian cells

   Depositor

   Robert Campbell

   Article

   Aggarwal et al Neurophotonics. 2024 Apr;11(2):024207. d

   Insert

   T-GECO1
   

   Use

   AAV

   Tags

   RSET peptide

   Expression

   Mammalian

   Promoter

   hSyn

   Available Since

   Aug. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. AAV-hSyn-IvfChr-citrine-KV2.1

    Plasmid

    #221615

    Purpose

    A recombinant AAV2 plasmid encoding vfChrimson-citrine with trafficking enhancement and soma targeting with KV2.1 motif.

    Depositor

    John Lin

    Article

    Mermet-Joret et al eLife 2023 12:RP90327

    Insert

    vfChrimson-citrine with membrane trafficking enhancement and soma targeting
    

    Use

    AAV

    Mutation

    vfChrimson-citrine with membrane trafficking enha…

    Promoter

    Human Synapsin

    Available Since

    Aug. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. AAV-hSyn-ZipT-mScarlet-KV2.1

    Plasmid

    #221617

    Purpose

    A recombinant AAV2 plasmid encoding the ZipACR I151V mutant and soma targeting with KV2.1 motif.

    Depositor

    John Lin

    Article

    Mermet-Joret et al eLife 2023 12:RP90327

    Insert

    ZipACR (I151T)-mScarlet with soma targeting
    

    Use

    AAV

    Mutation

    ZipACR (I151T) with soma targeting

    Promoter

    Human Synapsin

    Available Since

    Aug. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. AAV-hSyn-ZipV-mScarlet-KV2.1

    Plasmid

    #221616

    Purpose

    A recombinant AAV2 plasmid encoding the ZipACR I151T mutant and soma targeting with KV2.1 motif.

    Depositor

    John Lin

    Article

    Mermet-Joret et al eLife 2023 12:RP90327

    Insert

    ZipACR (I151V)-mScarlet with soma targeting
    

    Use

    AAV

    Mutation

    ZipACR (I151V) with soma targeting

    Promoter

    Human Synapsin

    Available Since

    Aug. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. AAV-hSyn-PiGM-Iq(D387A eGFP)

    Plasmid

    #221603

    Purpose

    A recombinant AAV2 plasmid encoding the light insensitive PiGM-Iq system with CRY2PHR(D387A), CIBN and EGFP as expression marker. hSynapsin promoter for panneuronal expression.

    Depositor

    John Lin

    Insert

    PiGM-Iq (D387A, eGFP)
    

    Use

    AAV

    Mutation

    RGS2 1-53 truncation, CRYPHR D387A

    Promoter

    Human Synapsin

    Available Since

    Aug. 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-CAG-fDIO-ArgiNLS-AausFP1

    Plasmid

    #220605

    Purpose

    Flp-dependent expression of a single-cell discriminating version of AausFP1 fluorescent protein.

    Depositor

    Sam Golden

    Article

    Szelenyi et al Proc Natl Acad Sci U S A. 2024 Aug 6;121

    Insert

    AausFP1
    

    Use

    AAV

    Tags

    ArgiNLS

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    Aug. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-EF1a-ArgiNLS-mVenus-Q69M(ME)

    Plasmid

    #220597

    Purpose

    Constitutive expression of a single-cell discriminating version of mVenus-Q69M (ME) fluorescent protein.

    Depositor

    Sam Golden

    Article

    Szelenyi et al Proc Natl Acad Sci U S A. 2024 Aug 6;121

    Insert

    mVenus-Q69M (ME)
    

    Use

    AAV

    Tags

    ArgiNLS

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    July 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAAV-CAG-FLEX-ArgiNLS-EGFP

    Plasmid

    #220601

    Purpose

    Cre-dependent expression of a single-cell discriminating version of EGFP fluorescent protein

    Depositor

    Sam Golden

    Article

    Szelenyi et al Proc Natl Acad Sci U S A. 2024 Aug 6;121

    Insert

    EGFP
    

    Use

    AAV and Cre/Lox

    Tags

    ArgiNLS

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    July 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-CMV-dSa VP64 Hbb

    Plasmid

    #99693

    Purpose

    Expresses dSa Cas9 fused to gold standard VP64 activator domain and Sa sgRNA for Hbb promoter, vector allows for activation of mouse Hbb, can be packaged and delivered as AAV

    Depositor

    George Church

    Article

    Vora et al bioRxiv 2018. 298620

    Insert

    dCas9 and gRNA targeting Hbb (gRNA: GGGGTAAGGGGAGCAAGGTC) (Hbb Synthetic, Mouse)
    

    Use

    AAV and CRISPR

    Tags

    VP64

    Mutation

    dead Cas9

    Available Since

    May 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAAV-hSyn-DIO-GCaMP6f-WPRE

    Plasmid

    #216275

    Purpose

    AAV vector with hSynapsin promoter and DIO Lox sites for Cre-On expression of green fluorescent calcium indicator GCaMP6f

    Depositor

    Guohong Cui

    Article

    Meng et al Neuron. 2018 May 16;98(4):707-717.e4. do

    Insert

    GCaMP6f
    

    Use

    AAV and Cre/Lox

    Tags

    6XHIS and Xpress

    Promoter

    human Synapsin 1 (hSyn)

    Available Since

    May 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pMV2 AAV-RapaInducible-NFZ-HGF

    Plasmid

    #188749

    Purpose

    Rapamycin inducible AAV vector expressing HGF

    Depositor

    Michael Bassik, Lacra Bintu

    Article

    Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038

    Insert

    HGF (HGF Human)
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    Rapamycin inducible

    Available Since

    May 7, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pJT314 AAV-Rapamycin Inducible-NZ-Citrine

    Plasmid

    #202063

    Purpose

    Inducible AAV activator

    Depositor

    Michael Bassik, Lacra Bintu

    Article

    Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038

    Insert

    AAV-Rapamycin Inducible-NZ-Citrine
    

    Use

    AAV; Aav with reporter

    Expression

    Mammalian

    Mutation

    ITR deletion

    Available Since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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