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lentiCRISPR v2-sgSLC11A2

Plasmid

#251684

Purpose

gRNA to knock out SLC11A2 in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

SLC11A2 solute carrier family 11 member 2 (SLC11A2 Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgSLC25A39-2

Plasmid

#251688

Purpose

gRNA to knock out SLC25A39 in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

SLC25A39 solute carrier family 25 member 39 (SLC25A39 Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgMT1E-1

Plasmid

#251690

Purpose

gRNA to knock out MT1E in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

MT1E metallothionein 1E (MT1E Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgMT1E-2

Plasmid

#251691

Purpose

gRNA to knock out MT1E in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

MT1E metallothionein 1E (MT1E Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgMT1X-1

Plasmid

#251692

Purpose

gRNA to knock out MT1X in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

MT1X metallothionein 1X (MT1X Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgMT1X-2

Plasmid

#251693

Purpose

gRNA to knock out MT1X in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

MT1X metallothionein 1X (MT1X Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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AG0057 LGA (DIO-mGlp1r)

Plasmid

#249035

Purpose

Expression of Wild Type Mouse Glp1r, Cre dependent under hSyn promoter

Depositor

Ali Guler

Article

Godschall et al bioRxiv [Preprint]. 2025 Jun 14:2024.12.

Insert

mGlp1r

Use

AAV

Tags

FLAG and HA

Promoter

hSyn

Available Since

Dec. 17, 2025

Availability

Academic Institutions and Nonprofits only

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AG0058 LGA (DIO-mGlp1r-S33W)

Plasmid

#249036

Purpose

Expression of Mutant Mouse Glp1r-S33W, Cre dependent under hSyn promoter

Depositor

Ali Guler

Article

Godschall et al bioRxiv [Preprint]. 2025 Jun 14:2024.12.

Insert

mGlp1r (S33W)

Use

AAV

Tags

FLAG and HA

Mutation

33S to 33W

Promoter

hSyn

Available Since

Dec. 17, 2025

Availability

Academic Institutions and Nonprofits only

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AG0053 LGA (DIO-hGLP1R)

Plasmid

#249034

Purpose

Expression of Wild Type Human GLP1R, Cre dependent, under hSyn promoter

Depositor

Ali Guler

Article

Godschall et al bioRxiv [Preprint]. 2025 Jun 14:2024.12.

Insert

hGlp1r

Use

AAV

Tags

FLAG

Promoter

hSyn

Available Since

Dec. 17, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-GRAB-HaloDAmut

Plasmid

#234409

Purpose

Expresses the chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut in neurons

Depositor

Yulong Li

Article

Zheng et al Science. 2025 Jun 5;388: 6751. doi: http

Insert

GPCR activation based chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut

Use

AAV

Promoter

hSyn

Available Since

Sept. 19, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1-Ub-Myc-LgBiT

Plasmid

#241817

Purpose

Expresses Myc-tagged and LgBiT-tagged Ubiquitin for use with the Promega HiBiT system

Depositor

Ethan Lee

Article

Kassel et al Nat Commun. 2025 Jun 5;16(1):5248. doi:

Insert

Ubiquitin

Tags

LgBiT and Myc

Expression

Mammalian

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-TNT4-Zfr-P2A-HA-luciferase

Plasmid

#223188

Purpose

Plasmid containing the Zfr/Firefly luciferase cassette. Translation of luciferase is controlled by splicing modulation of the Zfr by risdiplam.

Depositor

Yuxuan Guo

Article

Chen et al Nat Cardiovasc Res. 2025 Jun 13. doi: 10

Insert

luciferase (LOC116160065 firefly)

Use

AAV

Tags

HA and engineered P2A

Promoter

TNNT2

Available Since

June 18, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-TNT4-Zfr-P2A-HA-YAP5SA

Plasmid

#223189

Purpose

Plasmid containing the Zfr/YAP5SA cassette. Translation of YAP5SA is controlled by splicing modulation of the Zfr by risdiplam.

Depositor

Yuxuan Guo

Article

Chen et al Nat Cardiovasc Res. 2025 Jun 13. doi: 10

Insert

YAP5SA (Yap1 Mouse)

Use

AAV

Tags

HA and engineered P2A

Mutation

S61A, S109A, S127A, S164A, S381A

Promoter

TNNT2

Available Since

June 18, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_msfGFP-HMGB1-Mut-11G3F3G

Plasmid

#237626

Purpose

For overexpression of msfGFP-HMGB1-Mut-11G3F3G

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HMGB1-Mut-11G3F3G (HMGB1 Human)

Tags

msfGFP

Expression

Mammalian

Mutation

11G3F3G

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-HP1a-gRNA-2

Plasmid

#237635

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HP1a gRNA (CBX5 Human)

Use

CRISPR

Tags

mCherry

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_msfGFP-HMGB1-Shuffled 9

Plasmid

#237657

Purpose

For overexpression of msfGFP-HMGB1-Shuffled 9

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HMGB1-Shuffled 9 (HMGB1 Human)

Tags

msfGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_msfGFP-HMGB1-KS-FtoW

Plasmid

#237660

Purpose

For overexpression of msfGFP-HMGB1-KS-FtoW

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HMGB1-KS-FtoW (HMGB1 Human)

Tags

msfGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_mEGFP-SS18-SSX1-KS

Plasmid

#237679

Purpose

For overexpression of mEGFP-SS18-SSX1-KS

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

SS18-SSX1-KS (SS18, SSX1 Human)

Tags

mEGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_msfGFP-HMGB1-KS-FtoY

Plasmid

#237659

Purpose

For overexpression of msfGFP-HMGB1-KS-FtoY

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HMGB1-KS-FtoY (HMGB1 Human)

Tags

msfGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_mEGFP-SS18-SSX2-KS

Plasmid

#237680

Purpose

For overexpression of mEGFP-SS18-SSX2-KS

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

SS18-SSX2-KS (SS18, SSX2 Human)

Tags

mEGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge