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Curious about how, exactly, Cas9 does what it does? Dive into the structural biology of Cas9 for an answer!

A review of the common antibiotic resistances genes used in bacteria.

Get a behind-the-scenes look at how we've adapted video production during COVID-19.

Marc Zimmer's book, The State of Science, examines broad issues in science including racism and sexism, peer-review, funding, CRISPR, and the politicization of science.

Sarting a journal club? Read our guide to the logistics of forming a journal club and find different formats to hold the journal club discussion.

The tumor microenvironment is the cellular milieu that surrounds a tumor and contains immune cells, blood vessels, cells, and signaling molecules. What goes on in the cancer microenvironment affects and is affected and can either promote or repress tumor growth.

Resources to help improve precision genome editing through homology directed repair in experiments with CRISPR nucleases.

Learn how to measure your fluorescent protein's photostability and get the most out of your next fluorescent imaging experiment.

Create a more sustainable lab by making small changes in your day-to-day or aim for long-term conservation goals. Find easy action items in the blog post.

Addgenie Eric Perkins curates Addgene resources you can use in your chromatin research.

Learn how to use the pPSU plasmids to generate affordable DNA ladders.

Listen to learn about Crystal Shih's career path in industry and management, and get advice on how to succeed in your own career.

Get your fly research started with this quick guide to working with drosophila.

Take behind-the-scenes look at the isolation of a thermostable Cas9, IgnaviCas9, from Yellowstone and learn about the advantages of using a thermostable Cas9 protein.

Stochastic multicolor labeling is a popular technique to label individual cells with different colors and allows for lineage tracing of cell populations over time. Read this blog post to learn about the different systems for various organisms.

Emmanuelle Charpentier and Jennifer Doudna awarded for their CRISPR/Cas9 research at the 2014 Johnson & Johnson's Dr. Paul Janssen Award dinner.

Learn how stem cell researchers use reprogramming and transdifferentiation techniques to convert cells from one type into another.

Announcing Addgene's new Intro to the Lab Bench, a collection of protocols, videos, and quizzes to help guide those new to working in the lab.

Learn about the different types of stem cells in this guide. In particular, we discuss the pros and cons of using embryonic stem cells and adult stem cells and using induced pluripotent stem cells (iPSCs) as a model for regenerative medicine.

Lab protocol to determine purity and concentration of recombinant antibodies using ready-to-use biosafe Coomassie stain and ImageJ software.