962 results

If you’re using CRISPR to make a genome edit, how do you know if your experiment was successful? Try using fluorescent CRISPR reporters like SRIRACCHA and GEmCherry2.

May 26, 2020, 1:15 p.m.

SPARC is a tool that labels a fraction of a genetically-defined subset of cells. The result: easy visualization of individual, non-overlapping cells.

May 21, 2020, 1:15 p.m.

Ginkgo Bioworks and Addgene are synthesizing and distributing thousands of plasmids for COVID-19 research. Read to learn more about these constructs

May 19, 2020, 1:15 p.m.

Find a list of databases and resources for COVID-19 research and hear from the creators of these databases.

May 12, 2020, 1:15 p.m.

Scientists at Beam Therapeutics have found a way to improve editing in primary human cells using evolved adenine base editors called ABE8.

May 7, 2020, 1:15 p.m.

With the limitations of qRT-PCR based COVID-19 testing, scientists develop CRISPR-based diagnostic tools for COVID-19.

May 5, 2020, 1:15 p.m.

Addgene welcomes three new members to the Board of DIrectors: Khandan Baradaran, Frank Stegmeier, and Luk Vandenberghe.

April 28, 2020, 1:14 p.m.

Viral genome sequencing is a high-throughput method for determining AAV transgene identity and confirming the serotype.

April 23, 2020, 1:15 p.m.

Find tips for remote collaborations including scheduling regular meetings, maintaining informal communication, sharing documents, setting expectations, and meeting in person.

April 21, 2020, 1:14 p.m.

Learn how CRISPR-based diagnostic systems can easily detect nucleic acids of choice with high sensitivity, specificity and portability.

April 16, 2020, 1 p.m.

Scientists from UCSF identify 332 human proteins that the SARS-CoV-2 virus interacts with in cells in attempts to find druggable targets.

April 9, 2020, 1:15 p.m.

New to plasmids? Learn the basics of plasmids in this blog post and find out about the parts of a plasmid, how they are made, and how scientists can use them in the lab.

April 2, 2020, 6:17 p.m.

Plasmid incompatibility is the inability of different plasmids to be maintained in a cell. We’ll cover why this happens and how it might affect your experiment.

March 31, 2020, 1:15 p.m.

Find tips for working with RNA and simple protocols for extracting RNA without using a kit

March 24, 2020, 1:15 p.m.

New to remote working? Find tips for self-care, professional development, writing, balancing working from home with parenting, and more.

March 19, 2020, 1:15 p.m.

With the addition of ABE8, a faster and improved adenine base editor, scientists can now make base edits more efficiently and in more contexts.

March 17, 2020, 1:32 p.m.

A toolkit of synthetic promoters for transgene expression in AAV can be used for targeted gene expression in retinal cell types in mice, primate, and human retinas.

March 12, 2020, 1:15 p.m.

Learn about the latest CRISPR plasmids deposited at Addgene including plasmids for base editing, controlling gene expression in yeast and Caulobacter crescentus, multiplexed gRNA for human pluripotent stem cells, CRISPR-based DNA demethylation.

March 10, 2020, 1:15 p.m.

Addgene's AAV Data Hub is a place for researchers to find and share experimental parameters of using AAV. such as titer, injection site, and more.

March 5, 2020, 2:15 p.m.

Learn about new plasmids at Addgene including AAV split base editors, Ace2-mScarlet voltage indicator, CyanoGate MoClo cloning toolkit, and CreLite.

March 3, 2020, 2:15 p.m.