We narrowed to 51 results for: codon optimized

...manipulations start. Anthony Forster’s lab used codon optimization programs to engineer 14 chromoprotein sequences...

...SARS-CoV-2 ORFs and include plasmids that are codon optimized. Browse the collection or learn more about ...

...pathogenic alleles, or introduce a premature stop codon to render an RNA nonfunctional. In their quest to...directed evolution across the full ADAR2DD to further optimize cytidine deaminase activity. While RESCUE can ...

...20805792. 7. Stynen B., Van Dijck P., Tournu H. A CUG codon adapted two-hybrid system for the pathogenic fungus...channel interactions detected by a genetic system optimized for systematic studies of membrane protein interactions...

...develop an optimized photoactivatable CRISPR gene activation system, but settled on a different optimal fusion...researchers tested a variety of combinations to optimize both fusion proteins. The best performing combination...fusion protein combination. The optimized LACE system consisted of: 1) CIBN-dCas9-CIBN, where CIBN is the... would add the PCK upon reaching the amber stop codon, TAG. (To learn more about site-specific incorporation...

...edits produced synonymous changes, meaning the new codon corresponded to the same amino acid. Thus, bystander...patients. While these gRNAs would still need to be optimized and assessed for off-target risks, such a modular...

...enhance targeting to the nucleus, and several codon optimized Cas9 variants have been created in an effort...

... active in mammalian cells compared to the codon-optimized wild-type piggyBac transposase.  piggyBac ...

... to the use of exon skipping, alternative start codons, and/or the phenomenon of transcriptional adaptation...and robust gene silencing (following initial optimization of the amiRNA). Although downstream work is ...

...synaptic glutamate response. They generated variants optimized for different applications (v82 has higher affinity...indicator (GEVI) called JEDI-2P (Liu et al. 2022) optimized for two-photon imaging. They use a unique and ...multiparameter screen for accelerated development and optimization of soluble genetically encoded fluorescent biosensors...variety of imaging conditions (155 μs and <0.1 °C in optimal conditions). While B-gTEMP itself is a significant...viral prep here: pAAV.hSyn.FLEX.iGluSnFR3.v857.PDGFR.codonopt    Aggarwal A, et al. Glutamate indicators ...

...lab modified the nuclear localization signals and codon usage BE4 to create BE4max and AncBE4max with a ...cytidine and adenine base editors by expression optimization and ancestral reconstruction. Nature Biotechnology...