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PPRE X3-TK-luc Citations (54)

Plasmid Article: ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand.
Kim JB, Wright HM, Wright M, Spiegelman BM Proc Natl Acad Sci U S A 1998 Apr 14;95(8):4333-7.
PubMed Journal

Articles Citing PPRE X3-TK-luc

Articles
Identification of Arx transcriptional targets in the developing basal forebrain. Fulp CT, Cho G, Marsh ED, Nasrallah IM, Labosky PA, Golden JA. Hum Mol Genet. 2008 Dec 1;17(23):3740-60. doi: 10.1093/hmg/ddn271. Epub 2008 Sep 16. PubMed
Salacia oblonga extract increases glucose transporter 4-mediated glucose uptake in L6 rat myotubes: role of mangiferin. Giron MD, Sevillano N, Salto R, Haidour A, Manzano M, Jimenez ML, Rueda R, Lopez-Pedrosa JM. Clin Nutr. 2009 Oct;28(5):565-74. doi: 10.1016/j.clnu.2009.04.018. Epub 2009 May 23. PubMed
Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton. Almeida M, Ambrogini E, Han L, Manolagas SC, Jilka RL. J Biol Chem. 2009 Oct 2;284(40):27438-48. doi: 10.1074/jbc.M109.023572. Epub 2009 Aug 5. PubMed
DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. Ansems M, Hontelez S, Looman MW, Karthaus N, Bult P, Bonenkamp JJ, Jansen JH, Sweep FC, Span PN, Adema GJ. J Natl Cancer Inst. 2010 Jan 6;102(1):54-68. doi: 10.1093/jnci/djp441. Epub 2009 Dec 14. PubMed
Obesity reduces bone density associated with activation of PPARgamma and suppression of Wnt/beta-catenin in rapidly growing male rats. Chen JR, Lazarenko OP, Wu X, Tong Y, Blackburn ML, Shankar K, Badger TM, Ronis MJ. PLoS One. 2010 Oct 28;5(10):e13704. doi: 10.1371/journal.pone.0013704. PubMed
Therapeutic potential of panduratin A, LKB1-dependent AMP-activated protein kinase stimulator, with activation of PPARalpha/delta for the treatment of obesity. Kim D, Lee MS, Jo K, Lee KE, Hwang JK. Diabetes Obes Metab. 2011 Jul;13(7):584-93. doi: 10.1111/j.1463-1326.2011.01379.x. PubMed
Organotins are potent activators of PPARgamma and adipocyte differentiation in bone marrow multipotent mesenchymal stromal cells. Yanik SC, Baker AH, Mann KK, Schlezinger JJ. Toxicol Sci. 2011 Aug;122(2):476-88. doi: 10.1093/toxsci/kfr140. Epub 2011 May 27. PubMed
Piperidine alkaloids from Piper retrofractum Vahl. protect against high-fat diet-induced obesity by regulating lipid metabolism and activating AMP-activated protein kinase. Kim KJ, Lee MS, Jo K, Hwang JK. Biochem Biophys Res Commun. 2011 Jul 22;411(1):219-25. doi: 10.1016/j.bbrc.2011.06.153. Epub 2011 Jun 29. PubMed
Stereoisomers ginsenosides-20(S)-Rg(3) and -20(R)-Rg(3) differentially induce angiogenesis through peroxisome proliferator-activated receptor-gamma. Kwok HH, Guo GL, Lau JK, Cheng YK, Wang JR, Jiang ZH, Keung MH, Mak NK, Yue PY, Wong RN. Biochem Pharmacol. 2012 Apr 1;83(7):893-902. doi: 10.1016/j.bcp.2011.12.039. Epub 2012 Jan 4. PubMed
5,7-Dimethoxyflavone, an activator of PPARalpha/gamma, inhibits UVB-induced MMP expression in human skin fibroblast cells. Kim JK, Mun S, Kim MS, Kim MB, Sa BK, Hwang JK. Exp Dermatol. 2012 Mar;21(3):211-6. doi: 10.1111/j.1600-0625.2011.01435.x. PubMed
Ginsenoside Rb(1) induces type I collagen expression through peroxisome proliferator-activated receptor-delta. Kwok HH, Yue PY, Mak NK, Wong RN. Biochem Pharmacol. 2012 Aug 15;84(4):532-9. doi: 10.1016/j.bcp.2012.05.023. Epub 2012 Jun 9. PubMed
The corepressor NCoR1 antagonizes PGC-1alpha and estrogen-related receptor alpha in the regulation of skeletal muscle function and oxidative metabolism. Perez-Schindler J, Summermatter S, Salatino S, Zorzato F, Beer M, Balwierz PJ, van Nimwegen E, Feige JN, Auwerx J, Handschin C. Mol Cell Biol. 2012 Dec;32(24):4913-24. doi: 10.1128/MCB.00877-12. Epub 2012 Oct 1. PubMed
15-Deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) protects neurons from oxidative death via an Nrf2 astrocyte-specific mechanism independent of PPARgamma. Haskew-Layton RE, Payappilly JB, Xu H, Bennett SA, Ratan RR. J Neurochem. 2013 Feb;124(4):536-47. doi: 10.1111/jnc.12107. Epub 2013 Jan 3. PubMed
Disruption of Stard10 gene alters the PPARalpha-mediated bile acid homeostasis. Ito M, Yamanashi Y, Toyoda Y, Izumi-Nakaseko H, Oda S, Sugiyama A, Kuroda M, Suzuki H, Takada T, Adachi-Akahane S. Biochim Biophys Acta. 2013 Feb;1831(2):459-68. doi: 10.1016/j.bbalip.2012.11.008. Epub 2012 Nov 28. PubMed
Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARalpha). Thomas M, Burk O, Klumpp B, Kandel BA, Damm G, Weiss TS, Klein K, Schwab M, Zanger UM. Mol Pharmacol. 2013 Mar;83(3):709-18. doi: 10.1124/mol.112.082503. Epub 2013 Jan 7. PubMed
Mechanisms Mediating the Effects of gamma-Tocotrienol When Used in Combination with PPARgamma Agonists or Antagonists on MCF-7 and MDA-MB-231 Breast Cancer Cells. Malaviya A, Sylvester PW. Int J Breast Cancer. 2013;2013:101705. doi: 10.1155/2013/101705. Epub 2013 Jan 28. PubMed
Curcumin inhibits oxLDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation. Min KJ, Um HJ, Cho KH, Kwon TK. Food Chem Toxicol. 2013 Aug;58:77-85. doi: 10.1016/j.fct.2013.04.008. Epub 2013 Apr 16. PubMed
Cubilin expression is monoallelic and epigenetically augmented via PPARs. Aseem O, Barth JL, Klatt SC, Smith BT, Argraves WS. BMC Genomics. 2013 Jun 18;14:405. doi: 10.1186/1471-2164-14-405. PubMed
Divergence between human and murine peroxisome proliferator-activated receptor alpha ligand specificities. Oswal DP, Balanarasimha M, Loyer JK, Bedi S, Soman FL, Rider SD Jr, Hostetler HA. J Lipid Res. 2013 Sep;54(9):2354-65. doi: 10.1194/jlr.M035436. Epub 2013 Jun 24. PubMed
Constituents from Terminalia species increase PPARalpha and PPARgamma levels and stimulate glucose uptake without enhancing adipocyte differentiation. Yang MH, Vasquez Y, Ali Z, Khan IA, Khan SI. J Ethnopharmacol. 2013 Sep 16;149(2):490-8. doi: 10.1016/j.jep.2013.07.003. Epub 2013 Jul 10. PubMed
Screening of medicinal plants for PPARalpha and PPARgamma activation and evaluation of their effects on glucose uptake and 3T3-L1 adipogenesis. Yang MH, Avula B, Smillie T, Khan IA, Khan SI. Planta Med. 2013 Aug;79(12):1084-95. doi: 10.1055/s-0033-1350620. Epub 2013 Jul 22. PubMed
Panduratin A, an activator of PPAR-alpha/delta, suppresses the development of oxazolone-induced atopic dermatitis-like symptoms in hairless mice. Kim MS, Pyun HB, Hwang JK. Life Sci. 2014 Mar 28;100(1):45-54. doi: 10.1016/j.lfs.2014.01.076. Epub 2014 Feb 11. PubMed
Synergistic Antiproliferative Effects of Combined gamma -Tocotrienol and PPAR gamma Antagonist Treatment Are Mediated through PPAR gamma -Independent Mechanisms in Breast Cancer Cells. Malaviya A, Sylvester PW. PPAR Res. 2014;2014:439146. doi: 10.1155/2014/439146. Epub 2014 Mar 4. PubMed
A single amino acid change humanizes long-chain fatty acid binding and activation of mouse peroxisome proliferator-activated receptor alpha. Oswal DP, Alter GM, Rider SD Jr, Hostetler HA. J Mol Graph Model. 2014 Jun;51:27-36. doi: 10.1016/j.jmgm.2014.04.006. Epub 2014 Apr 29. PubMed
Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth. Hann SS, Tang Q, Zheng F, Zhao S, Chen J, Wang Z. Mol Cancer. 2014 Jun 13;13:149. doi: 10.1186/1476-4598-13-149. PubMed
Ligand binding and activation of PPARgamma by Firemaster(R) 550: effects on adipogenesis and osteogenesis in vitro. Pillai HK, Fang M, Beglov D, Kozakov D, Vajda S, Stapleton HM, Webster TF, Schlezinger JJ. Environ Health Perspect. 2014 Nov;122(11):1225-32. doi: 10.1289/ehp.1408111. Epub 2014 Jul 25. PubMed
In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo. Parks AJ, Pollastri MP, Hahn ME, Stanford EA, Novikov O, Franks DG, Haigh SE, Narasimhan S, Ashton TD, Hopper TG, Kozakov D, Beglov D, Vajda S, Schlezinger JJ, Sherr DH. Mol Pharmacol. 2014 Nov;86(5):593-608. doi: 10.1124/mol.114.093369. Epub 2014 Aug 26. PubMed
Soy protein isolate inhibits high-fat diet-induced senescence pathways in osteoblasts to maintain bone acquisition in male rats. Chen JR, Lazarenko OP, Blackburn ML, Badger TM, Ronis MJ. Endocrinology. 2015 Feb;156(2):475-87. doi: 10.1210/en.2014-1427. Epub 2014 Dec 9. PubMed
Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA. Buchner DA, Charrier A, Srinivasan E, Wang L, Paulsen MT, Ljungman M, Bridges D, Saltiel AR. J Biol Chem. 2015 Mar 6;290(10):6376-86. doi: 10.1074/jbc.M114.623736. Epub 2015 Jan 16. PubMed
Structurally-diverse, PPARgamma-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells. Watt J, Schlezinger JJ. Toxicology. 2015 May 4;331:66-77. doi: 10.1016/j.tox.2015.03.006. Epub 2015 Mar 14. PubMed
HIF2alpha-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma. Qiu B, Ackerman D, Sanchez DJ, Li B, Ochocki JD, Grazioli A, Bobrovnikova-Marjon E, Diehl JA, Keith B, Simon MC. Cancer Discov. 2015 Jun;5(6):652-67. doi: 10.1158/2159-8290.CD-14-1507. Epub 2015 Mar 31. PubMed
Activation of peroxisome proliferator-activated receptor alpha stimulates ADAM10-mediated proteolysis of APP. Corbett GT, Gonzalez FJ, Pahan K. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8445-50. doi: 10.1073/pnas.1504890112. Epub 2015 Jun 15. PubMed
CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor alpha in Human Liver. Makia NL, Goldstein JA. Mol Pharmacol. 2016 Jan;89(1):154-64. doi: 10.1124/mol.115.100255. Epub 2015 Oct 14. PubMed
PPARalpha (Peroxisome Proliferator-activated Receptor alpha) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition. Ramakrishnan SK, Khuder SS, Al-Share QY, Russo L, Abdallah SL, Patel PR, Heinrich G, Muturi HT, Mopidevi BR, Oyarce AM, Shah YM, Sanchez ER, Najjar SM. J Biol Chem. 2016 Apr 8;291(15):8121-9. doi: 10.1074/jbc.M116.714014. Epub 2016 Feb 4. PubMed
The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis. Leow SC, Poschmann J, Too PG, Yin J, Joseph R, McFarlane C, Dogra S, Shabbir A, Ingham PW, Prabhakar S, Leow MK, Lee YS, Ng KL, Chong YS, Gluckman PD, Stunkel W. Development. 2016 Mar 15;143(6):950-61. doi: 10.1242/dev.131573. Epub 2016 Feb 18. PubMed
Apple polyphenol extract improves insulin sensitivity in vitro and in vivo in animal models of insulin resistance. Manzano M, Giron MD, Vilchez JD, Sevillano N, El-Azem N, Rueda R, Salto R, Lopez-Pedrosa JM. Nutr Metab (Lond). 2016 Apr 30;13:32. doi: 10.1186/s12986-016-0088-8. eCollection 2016. PubMed
Generalized Concentration Addition modeling predicts mixture effects of environmental PPARgamma agonists. Watt J, Webster TF, Schlezinger JJ. Toxicol Sci. 2016 Jun 2. pii: kfw100. PubMed
Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice. Charrier A, Wang L, Stephenson EJ, Ghanta SV, Ko CW, Croniger CM, Bridges D, Buchner DA. Am J Physiol Endocrinol Metab. 2016 Nov 1;311(5):E869-E880. doi: 10.1152/ajpendo.00234.2016. Epub 2016 Sep 13. PubMed
Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein alpha. Song Z, Xiaoli AM, Zhang Q, Zhang Y, Yang EST, Wang S, Chang R, Zhang ZD, Yang G, Strich R, Pessin JE, Yang F. J Biol Chem. 2017 May 26;292(21):8918-8932. doi: 10.1074/jbc.M117.776229. Epub 2017 Mar 28. PubMed
Fatty Acids of CLA-Enriched Egg Yolks Can Induce Transcriptional Activation of Peroxisome Proliferator-Activated Receptors in MCF-7 Breast Cancer Cells. Koronowicz AA, Banks P, Master A, Domagala D, Piasna-Slupecka E, Drozdowska M, Sikora E, Laidler P. PPAR Res. 2017;2017:2865283. doi: 10.1155/2017/2865283. Epub 2017 Mar 26. PubMed
Plasmid transfection in bovine cells: Optimization using a realtime monitoring of green fluorescent protein and effect on gene reporter assay. Osorio JS, Bionaz M. Gene. 2017 Aug 30;626:200-208. doi: 10.1016/j.gene.2017.05.025. Epub 2017 May 10. PubMed
A PPARgamma-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis. Lee A, Papangeli I, Park Y, Jeong HN, Choi J, Kang H, Jo HN, Kim J, Chun HJ. Sci Rep. 2017 May 31;7(1):2528. doi: 10.1038/s41598-017-02852-4. PubMed
In Vitro Differentiation of Preosteoblast-Like Cells, MC3T3-E1, to Adipocytes Is Enhanced by 1,25(OH)2 Vitamin D3. Pendleton E, Chandar N. Front Endocrinol (Lausanne). 2017 Jun 16;8:128. doi: 10.3389/fendo.2017.00128. eCollection 2017. PubMed
Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance. Lee SY, Lee HY, Song JH, Kim GT, Jeon S, Song YJ, Lee JS, Hur JH, Oh HH, Park SY, Shim SM, Yoo HJ, Lee BC, Jiang XC, Choi CS, Park TS. Diabetes. 2017 Oct;66(10):2596-2609. doi: 10.2337/db16-1232. Epub 2017 Jul 11. PubMed
SMARCD1 regulates senescence-associated lipid accumulation in hepatocytes. Inoue C, Zhao C, Tsuduki Y, Udono M, Wang L, Nomura M, Katakura Y. NPJ Aging Mech Dis. 2017 Aug 30;3:11. doi: 10.1038/s41514-017-0011-1. eCollection 2017. PubMed
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation. Halstead AM, Kapadia CD, Bolzenius J, Chu CE, Schriefer A, Wartman LD, Bowman GR, Arora VK. Elife. 2017 Nov 16;6. pii: 30862. doi: 10.7554/eLife.30862. PubMed
N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, Lichtman AH, Damaj MI, Di Marzo V, Mechoulam R. Neuropharmacology. 2019 Apr;148:320-331. doi: 10.1016/j.neuropharm.2018.03.020. Epub 2018 Mar 19. PubMed
Lanthionine synthetase C-like protein 2 (LanCL2) is important for adipogenic differentiation. Dutta D, Lai KY, Reyes-Ordonez A, Chen J, van der Donk WA. J Lipid Res. 2018 Aug;59(8):1433-1445. doi: 10.1194/jlr.M085274. Epub 2018 Jun 7. PubMed
Identification and characterization of phytocannabinoids as novel dual PPARalpha/gamma agonists by a computational and in vitro experimental approach. D'Aniello E, Fellous T, Iannotti FA, Gentile A, Allara M, Balestrieri F, Gray R, Amodeo P, Vitale RM, Di Marzo V. Biochim Biophys Acta Gen Subj. 2019 Mar;1863(3):586-597. doi: 10.1016/j.bbagen.2019.01.002. Epub 2019 Jan 3. PubMed
MiR-30c/PGC-1beta protects against diabetic cardiomyopathy via PPARalpha. Yin Z, Zhao Y, He M, Li H, Fan J, Nie X, Yan M, Chen C, Wang DW. Cardiovasc Diabetol. 2019 Jan 11;18(1):7. doi: 10.1186/s12933-019-0811-7. PubMed
EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes. Moren B, Hansson B, Negoita F, Fryklund C, Lundmark R, Goransson O, Stenkula KG. Mol Biol Cell. 2019 May 1;30(10):1147-1159. doi: 10.1091/mbc.E18-10-0680. Epub 2019 Feb 27. PubMed
The Furan Fatty Acid 9M5 Acts as a Partial Ligand to Peroxisome Proliferator-Activated Receptor gamma and Enhances Adipogenesis in 3T3-L1 Preadipocytes. Lauvai J, Becker AK, Lehnert K, Schumacher M, Hieronimus B, Vetter W, Graeve L. Lipids. 2019 May;54(5):277-288. doi: 10.1002/lipd.12152. PubMed
RNase MCPIP1 regulates hepatic peroxisome proliferator-activated receptor gamma via TXNIP/PGC-1alpha pathway. Pydyn N, Kadluczka J, Kus E, Pospiech E, Losko M, Fu M, Jura J, Kotlinowski J. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1458-1471. doi: 10.1016/j.bbalip.2019.06.006. Epub 2019 Jun 8. PubMed
Essential role of the PGC-1alpha/PPARbeta axis in Ucp3 gene induction. Lima TI, Guimaraes D, Sponton CH, Bajgelman MC, Palameta S, Toscaro JM, Reis O, Silveira LR. J Physiol. 2019 Jun 22. doi: 10.1113/JP278006. PubMed

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