pcDNA4/TO/cmycDrosha Citations (7)
Originally described in: The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis.Landthaler M, Yalcin A, Tuschl T Curr Biol. 2004 Dec 14. 14(23):2162-7. PubMed Journal
Articles Citing pcDNA4/TO/cmycDrosha
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Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization.
Tang X, Zhang Y, Tucker L, Ramratnam B.
Nucleic Acids Res. 2010 Oct;38(19):6610-9. doi: 10.1093/nar/gkq547. Epub 2010 Jun 16.
PubMed
Associated Plasmids |
| TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs. Ballarino M, Jobert L, Dembele D, de la Grange P, Auboeuf D, Tora L. Oncogene. 2013 Sep 26;32(39):4646-55. doi: 10.1038/onc.2012.490. Epub 2012 Nov 5. PubMed |
| Sequence-based design of bioactive small molecules that target precursor microRNAs. Velagapudi SP, Gallo SM, Disney MD. Nat Chem Biol. 2014 Apr;10(4):291-7. doi: 10.1038/nchembio.1452. Epub 2014 Feb 9. PubMed |
| Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour. Torrezan GT, Ferreira EN, Nakahata AM, Barros BD, Castro MT, Correa BR, Krepischi AC, Olivieri EH, Cunha IW, Tabori U, Grundy PE, Costa CM, de Camargo B, Galante PA, Carraro DM. Nat Commun. 2014 Jun 9;5:4039. doi: 10.1038/ncomms5039. PubMed |
| Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK. Nat Commun. 2014 Oct 29;5:5202. doi: 10.1038/ncomms6202. PubMed |
| METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Pandolfini L, Barbieri I, Bannister AJ, Hendrick A, Andrews B, Webster N, Murat P, Mach P, Brandi R, Robson SC, Migliori V, Alendar A, d'Onofrio M, Balasubramanian S, Kouzarides T. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25. PubMed |
| The orf virus (ORFV) protein OV20.0 interacts with the microprocessor complex subunit DGCR8 to regulate miRNA biogenesis and ORFV infection. Liao GR, Tseng YY, Tseng CY, Lo CY, Hsu WL. FEBS Lett. 2021 Dec;595(23):2897-2908. doi: 10.1002/1873-3468.14231. Epub 2021 Nov 22. PubMed |
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