1
Plasmid 11767: p3TP-lux
  • 3TP

  • pGL2-Basic
    (Search Vector Database)

  • Promega

  • Mammalian Expression, Luciferase

  • 5600

  • XhoI

  • No

  • EcoRI

  • No

  • LucNrev List of Sequencing Primers

  • Ampicillin

  • DH5alpha

  • 37

  • High Copy

  • This plasmid was constructed at the Massague lab at MSKCC. Please acknowledge both the Wrana and Massague labs in your publication.

  • View sequences (2)
  • Joan Massague

  • Jeff Wrana

  • UBMTA
    Luciferase Limited Use Label License

Comments: 

A luciferase reporter gene with the 3TP
promoter that contains three consecutive TPA response elements (TREs) and a portion of the plasminogen activator
inhibitor 1 (PAI-1) promoter region.

Addgene has sequenced a portion of this plasmid for verification. Full plasmid sequence is available only if provided by the depositing laboratory.

Article: TGF beta signals through a heteromeric protein kinase receptor complex. Wrana et al (Cell. 1992 Dec 11. 71(6):1003-14. PubMed)

Please acknowledge the principal investigator and cite this article if you use this plasmid in a publication. Also, please include the text "Addgene plasmid 11767" in your Materials and Methods section.