VRQR-ABEmax Citations (4)

Originally described in: Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.
Huang TP, Zhao KT, Miller SM, Gaudelli NM, Oakes BL, Fellmann C, Savage DF, Liu DR Nat Biotechnol. 2019 May 20. pii: 10.1038/s41587-019-0134-y. doi: 10.1038/s41587-019-0134-y. PubMed Journal

Articles Citing VRQR-ABEmax

Articles
Modeling Niemann-Pick disease type C in a human haploid cell line allows for patient variant characterization and clinical interpretation. Erwood S, Brewer RA, Bily TMI, Maino E, Zhou L, Cohn RD, Ivakine EA. Genome Res. 2019 Dec;29(12):2010-2019. doi: 10.1101/gr.250720.119. Epub 2019 Nov 21. PubMed Associated Plasmids BPK1520_puroR
In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice. Koblan LW, Erdos MR, Wilson C, Cabral WA, Levy JM, Xiong ZM, Tavarez UL, Davison LM, Gete YG, Mao X, Newby GA, Doherty SP, Narisu N, Sheng Q, Krilow C, Lin CY, Gordon LB, Cao K, Collins FS, Brown JD, Liu DR. Nature. 2021 Jan;589(7843):608-614. doi: 10.1038/s41586-020-03086-7. Epub 2021 Jan 6. PubMed Associated Plasmids hu6 HGPS sgRNA expression and ABE7.10max VRQR lentiviral plasmid hu6 HGPS sgRNA expression and ABE7.10max VRQR C terminal AAV vector
Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice. Chai AC, Cui M, Chemello F, Li H, Chen K, Tan W, Atmanli A, McAnally JR, Zhang Y, Xu L, Liu N, Bassel-Duby R, Olson EN. Nat Med. 2023 Feb;29(2):401-411. doi: 10.1038/s41591-022-02176-5. Epub 2023 Feb 16. PubMed
In vivo adenine base editing corrects newborn murine model of Hurler syndrome. Su J, Jin X, She K, Liu Y, Song L, Zhao Q, Xiao J, Li R, Deng H, Lu F, Yang Y. Mol Biomed. 2023 Feb 23;4(1):6. doi: 10.1186/s43556-023-00120-8. PubMed

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