pLOX-TERT-iresTK Citations (26)

Originally described in: Reversible immortalization of human primary cells by lentivector-mediated transfer of specific genes.
Salmon P, Oberholzer J, Occhiodoro T, Morel P, Lou J, Trono D Mol Ther. 2000 Oct . 2(4):404-14. PubMed Journal

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Articles Citing pLOX-TERT-iresTK

Articles
Controllable expansion of primary cardiomyocytes by reversible immortalization. Zhang Y, Nuglozeh E, Touré F, Schmidt AM, Vunjak-Novakovic G. Hum Gene Ther. 2009 Dec . 20(12):1687-96. PubMed
Reversibly immortalized human olfactory ensheathing glia from an elderly donor maintain neuroregenerative capacity. Lim F, Martin-Bermejo MJ, Garcia-Escudero V, Gallego-Hernandez MT, Garcia-Gomez A, Rabano A, Diaz-Nido J, Avila J, Moreno-Flores MT. Glia. 2010 Apr;58(5):546-58. doi: 10.1002/glia.20944. PubMed
Prevention of senescence progression in reversibly immortalized human ensheathing glia permits their survival after deimmortalization. García-Escudero V, García-Gómez A, Gargini R, Martín-Bermejo MJ, Langa E, de Yébenes JG, Delicado A, Avila J, Moreno-Flores MT, Lim F. Mol Ther. 2010 Feb . 18(2):394-403. PubMed
A neuroregenerative human ensheathing glia cell line with conditional rapid growth. Garcia-Escudero V, Gargini R, Gallego-Hernandez MT, Garcia-Gomez A, Martin-Bermejo MJ, Simon D, Delicado A, Moreno-Flores MT, Avila J, Lim F. Cell Transplant. 2011;20(2):153-66. doi: 10.3727/096368910X522108. Epub 2010 Aug 18. PubMed
Elevated expression of stromal palladin predicts poor clinical outcome in renal cell carcinoma. Gupta V, Bassi DE, Simons JD, Devarajan K, Al-Saleem T, Uzzo RG, Cukierman E. PLoS One. 2011;6(6):e21494. doi: 10.1371/journal.pone.0021494. Epub 2011 Jun 28. PubMed
Upregulation of CYP 450s expression of immortalized hepatocyte-like cells derived from mesenchymal stem cells by enzyme inducers. Sa-ngiamsuntorn K, Wongkajornsilp A, Kasetsinsombat K, Duangsa-ard S, Nuntakarn L, Borwornpinyo S, Akarasereenont P, Limsrichamrern S, Hongeng S. BMC Biotechnol. 2011 Sep 30;11:89. doi: 10.1186/1472-6750-11-89. PubMed
Development of immortalized hepatocyte-like cells from hMSCs. Wongkajornsilp A, Sa-Ngiamsuntorn K, Hongeng S. Methods Mol Biol. 2012;826:73-87. doi: 10.1007/978-1-61779-468-1_7. PubMed
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Shen H, Fridley BL, Song H, Lawrenson K, Cunningham JM, Ramus SJ, Cicek MS, Tyrer J, Stram D, Larson MC, Kobel M, Ziogas A, Zheng W, Yang HP, Wu AH, Wozniak EL, Woo YL, Winterhoff B, Wik E, Whittemore AS, Wentzensen N, Weber RP, Vitonis AF, Vincent D, Vierkant RA, Vergote I, Van Den Berg D, Van Altena AM, Tworoger SS, Thompson PJ, Tessier DC, Terry KL, Teo SH, Templeman C, Stram DO, Southey MC, Sieh W, Siddiqui N, Shvetsov YB, Shu XO, Shridhar V, Wang-Gohrke S, Severi G, Schwaab I, Salvesen HB, Rzepecka IK, Runnebaum IB, Rossing MA, Rodriguez-Rodriguez L, Risch HA, Renner SP, Poole EM, Pike MC, Phelan CM, Pelttari LM, Pejovic T, Paul J, Orlow I, Omar SZ, Olson SH, Odunsi K, Nickels S, Nevanlinna H, Ness RB, Narod SA, Nakanishi T, Moysich KB, Monteiro AN, Moes-Sosnowska J, Modugno F, Menon U, McLaughlin JR, McGuire V, Matsuo K, Adenan NA, Massuger LF, Lurie G, Lundvall L, Lubinski J, Lissowska J, Levine DA, Leminen A, Lee AW, Le ND, Lambrechts S, Lambrechts D, Kupryjanczyk J, Krakstad C, Konecny GE, Kjaer SK, Kiemeney LA, Kelemen LE, Keeney GL, Karlan BY, Karevan R, Kalli KR, Kajiyama H, Ji BT, Jensen A, Jakubowska A, Iversen E, Hosono S, Hogdall CK, Hogdall E, Hoatlin M, Hillemanns P, Heitz F, Hein R, Harter P, Halle MK, Hall P, Gronwald J, Gore M, Goodman MT, Giles GG, Gentry-Maharaj A, Garcia-Closas M, Flanagan JM, Fasching PA, Ekici AB, Edwards R, Eccles D, Easton DF, Durst M, du Bois A, Dork T, Doherty JA, Despierre E, Dansonka-Mieszkowska A, Cybulski C, Cramer DW, Cook LS, Chen X, Charbonneau B, Chang-Claude J, Campbell I, Butzow R, Bunker CH, Brueggmann D, Brown R, Brooks-Wilson A, Brinton LA, Bogdanova N, Block MS, Benjamin E, Beesley J, Beckmann MW, Bandera EV, Baglietto L, Bacot F, Armasu SM, Antonenkova N, Anton-Culver H, Aben KK, Liang D, Wu X, Lu K, Hildebrandt MA, Schildkraut JM, Sellers TA, Huntsman D, Berchuck A, Chenevix-Trench G, Gayther SA, Pharoah PD, Laird PW, Goode EL, Pearce CL. Nat Commun. 2013;4:1628. doi: 10.1038/ncomms2629. PubMed
LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Mao XG, Hutt-Cabezas M, Orr BA, Weingart M, Taylor I, Rajan AK, Odia Y, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG, Raabe EH. Oncotarget. 2013 Jul;4(7):1050-64. PubMed
TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome. Ochiai H, Miyamoto T, Kanai A, Hosoba K, Sakuma T, Kudo Y, Asami K, Ogawa A, Watanabe A, Kajii T, Yamamoto T, Matsuura S. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1461-6. doi: 10.1073/pnas.1317008111. Epub 2013 Dec 16. PubMed
Production of CMAH Knockout Preimplantation Embryos Derived From Immortalized Porcine Cells Via TALE Nucleases. Moon J, Lee C, Kim SJ, Choi JY, Lee BC, Kim JS, Jang G. Mol Ther Nucleic Acids. 2014 May 27;3:e166. doi: 10.1038/mtna.2014.15. PubMed
Src as a novel therapeutic target for endometriosis. Lawrenson K, Lee N, Torres HA, Lee JM, Brueggmann D, Rao PN, Noushmehr H, Gayther SA. Gynecol Oncol. 2014 Oct;135(1):100-7. doi: 10.1016/j.ygyno.2014.06.016. Epub 2014 Jun 24. PubMed
Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells. Ochiai H, Sugawara T, Sakuma T, Yamamoto T. Sci Rep. 2014 Nov 20;4:7125. doi: 10.1038/srep07125. PubMed
FoxO3a suppresses the senescence of cardiac microvascular endothelial cells by regulating the ROS-mediated cell cycle. Qi XF, Chen ZY, Xia JB, Zheng L, Zhao H, Pi LQ, Park KS, Kim SK, Lee KJ, Cai DQ. J Mol Cell Cardiol. 2015 Apr;81:114-26. doi: 10.1016/j.yjmcc.2015.01.022. Epub 2015 Feb 2. PubMed
Apigenin inhibits pancreatic stellate cell activity in pancreatitis. Mrazek AA, Porro LJ, Bhatia V, Falzon M, Spratt H, Zhou J, Chao C, Hellmich MR. J Surg Res. 2015 Jun 1;196(1):8-16. doi: 10.1016/j.jss.2015.02.032. Epub 2015 Feb 19. PubMed
Efficient PRNP deletion in bovine genome using gene-editing technologies in bovine cells. Choi W, Kim E, Yum SY, Lee C, Lee J, Moon J, Ramachandra S, Malaweera BO, Cho J, Kim JS, Kim S, Jang G. Prion. 2015;9(4):278-91. doi: 10.1080/19336896.2015.1071459. PubMed
DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets. Hanaford AR, Archer TC, Price A, Kahlert UD, Maciaczyk J, Nikkhah G, Kim JW, Ehrenberger T, Clemons PA, Dancik V, Seashore-Ludlow B, Viswanathan V, Stewart ML, Rees MG, Shamji A, Schreiber S, Fraenkel E, Pomeroy SL, Mesirov JP, Tamayo P, Eberhart CG, Raabe EH. Clin Cancer Res. 2016 Mar 24. PubMed
Low p16INK4a Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone. Graham MK, Principessa L, Antony L, Meeker AK, Isaacs JT. Prostate. 2016 Nov 8. doi: 10.1002/pros.23276. PubMed
Gene delivery of hypoxia-inducible VEGF targeting collagen effectively improves cardiac function after myocardial infarction. Xia JB, Wu HY, Lai BL, Zheng L, Zhou DC, Chang ZS, Mao CZ, Liu GH, Park KS, Zhao H, Kim SK, Song GH, Cai DQ, Qi XF. Sci Rep. 2017 Oct 16;7(1):13273. doi: 10.1038/s41598-017-13547-1. PubMed
VEGF/PKD-1 signaling mediates arteriogenic gene expression and angiogenic responses in reversible human microvascular endothelial cells with extended lifespan. Best B, Moran P, Ren B. Mol Cell Biochem. 2018 Sep;446(1-2):199-207. doi: 10.1007/s11010-018-3286-z. Epub 2018 Jan 29. PubMed
Generation of an immortalized human choroid endothelial cell line (iChEC-1) using an endothelial cell specific promoter. Giacalone JC, Miller MJ, Workalemahu G, Reutzel AJ, Ochoa D, Whitmore SS, Stone EM, Tucker BA, Mullins RF. Microvasc Res. 2019 May;123:50-57. doi: 10.1016/j.mvr.2018.12.002. Epub 2018 Dec 18. PubMed
A platform for artificial intelligence based identification of the extravasation potential of cancer cells into the brain metastatic niche. Oliver CR, Altemus MA, Westerhof TM, Cheriyan H, Cheng X, Dziubinski M, Wu Z, Yates J, Morikawa A, Heth J, Castro MG, Leung BM, Takayama S, Merajver SD. Lab Chip. 2019 Mar 27;19(7):1162-1173. doi: 10.1039/c8lc01387j. PubMed
Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction. Toubiana S, Gagliardi M, Papa M, Manco R, Tzukerman M, Matarazzo MR, Selig S. Elife. 2019 Nov 20;8. pii: 47859. doi: 10.7554/eLife.47859. PubMed
Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography. Oliver CR, Westerhof TM, Castro MG, Merajver SD. J Vis Exp. 2020 Aug 16;(162). doi: 10.3791/61654. PubMed
Mesenchymal stem cells overexpressing BMP-9 by CRISPR-Cas9 present high in vitro osteogenic potential and enhance in vivo bone formation. Freitas GP, Lopes HB, Souza ATP, Gomes MPO, Quiles GK, Gordon J, Tye C, Stein JL, Stein GS, Lian JB, Beloti MM, Rosa AL. Gene Ther. 2021 Dec;28(12):748-759. doi: 10.1038/s41434-021-00248-8. Epub 2021 Mar 8. PubMed
Generation of NKX2.5(GFP) Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts. Lopez-Muneta L, Linares J, Casis O, Martinez-Ibanez L, Gonzalez Miqueo A, Bezunartea J, Sanchez de la Nava AM, Gallego M, Fernandez-Santos ME, Rodriguez-Madoz JR, Aranguren XL, Fernandez-Aviles F, Segovia JC, Prosper F, Carvajal-Vergara X. Front Cell Dev Biol. 2022 Jan 21;9:797927. doi: 10.3389/fcell.2021.797927. eCollection 2021. PubMed

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