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Plasmid 16557: MadMyc-HA
  • MADMYC

  • c-MYC

  • H. sapiens (human)

  • MYC (MRTL, MYCC, bHLHe39, c-Myc)

  • HA

  • C terminal on insert

  • Dominant negative mutant

  • n/a
    (Search Vector Database)

  • Mammalian Expression

  • CMV-F List of Sequencing Primers

  • Amp (50ug/uL)

  • DH10B

  • 37

  • Unknown

  • View sequences (1)
  • View map

  • Bert Vogelstein

  • UBMTA

Comments: 

MADMYC: the amino
terminal transactivation domain of c-Myc (aa 1-263) was removed and replaced with the amino terminal transcriptional
repression domain (aa 1-38, the Sin3-interaction region) of Mad.

Addgene has sequenced a portion of this plasmid for verification. Full plasmid sequence is available only if provided by the depositing laboratory.

Article: Identification of CDK4 as a target of c-MYC. Hermeking et al (Proc Natl Acad Sci U S A. 2000 Feb 29. 97(5):2229-34. PubMed)

Please acknowledge the principal investigator and cite this article if you use this plasmid in a publication. Also, please include the text "Addgene plasmid 16557" in your Materials and Methods section.