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pGL3-NFAT luciferase Citations (25)

Plasmid Article: Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation.
Clipstone NA, Crabtree GR Nature. 1992 Jun 25. 357(6380):695-7.
PubMed Journal

Articles Citing pGL3-NFAT luciferase

Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc. Gajghate S, Hiyama A, Shah M, Sakai D, Anderson DG, Shapiro IM, Risbud MV. J Bone Miner Res. 2009 Jun;24(6):992-1001. doi: 10.1359/jbmr.090103. PubMed
Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc. Hiyama A, Gajghate S, Sakai D, Mochida J, Shapiro IM, Risbud MV. J Biol Chem. 2009 Apr 10;284(15):9824-34. doi: 10.1074/jbc.M807081200. Epub 2009 Jan 15. PubMed
A fluorescence-based assay to monitor transcriptional activity of NFAT in living cells. Rinne A, Blatter LA. J Physiol. 2010 Sep 1;588(Pt 17):3211-6. doi: 10.1113/jphysiol.2010.192419. Epub 2010 Jul 12. PubMed
RA-RAR-beta counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression. Puttagunta R, Schmandke A, Floriddia E, Gaub P, Fomin N, Ghyselinck NB, Di Giovanni S. J Cell Biol. 2011 Jun 27;193(7):1147-56. doi: 10.1083/jcb.201102066. Epub 2011 Jun 20. PubMed
Ovatodiolide Targets beta -Catenin Signaling in Suppressing Tumorigenesis and Overcoming Drug Resistance in Renal Cell Carcinoma. Ho JY, Hsu RJ, Wu CL, Chang WL, Cha TL, Yu DS, Yu CP. Evid Based Complement Alternat Med. 2013;2013:161628. doi: 10.1155/2013/161628. Epub 2013 May 26. PubMed
Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter. Tsao HW, Tai TS, Tseng W, Chang HH, Grenningloh R, Miaw SC, Ho IC. Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15776-81. doi: 10.1073/pnas.1304343110. Epub 2013 Sep 9. PubMed
The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma. Weissinger D, Tagscherer KE, Macher-Goppinger S, Haferkamp A, Wagener N, Roth W. Mol Cancer. 2013 Oct 10;12(1):120. doi: 10.1186/1476-4598-12-120. PubMed
Functional activities of mutant calcium-sensing receptors determine clinical presentations in patients with autosomal dominant hypocalcemia. Kinoshita Y, Hori M, Taguchi M, Watanabe S, Fukumoto S. J Clin Endocrinol Metab. 2014 Feb;99(2):E363-8. doi: 10.1210/jc.2013-3430. Epub 2013 Dec 2. PubMed
Tumor necrosis factor-alpha- and interleukin-1beta-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-kappaB axis: implications in inflammatory disc disease. Wang X, Wang H, Yang H, Li J, Cai Q, Shapiro IM, Risbud MV. Am J Pathol. 2014 Sep;184(9):2560-72. doi: 10.1016/j.ajpath.2014.06.006. Epub 2014 Jul 22. PubMed
Amplified lipid rafts of malignant cells constitute a target for inhibition of aberrantly active NFAT and melanoma tumor growth by the aminobisphosphonate zoledronic acid. Levin-Gromiko U, Koshelev V, Kushnir P, Fedida-Metula S, Voronov E, Fishman D. Carcinogenesis. 2014 Nov;35(11):2555-66. doi: 10.1093/carcin/bgu178. Epub 2014 Aug 20. PubMed
Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxin. Strack J, Heni H, Gilsbach R, Hein L, Aktories K, Orth JH. MBio. 2014 Nov 11;5(6):e02190. doi: 10.1128/mBio.02190-14. PubMed
The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins. Imam H, Bano AS, Patel P, Holla P, Jameel S. Sci Rep. 2015 Mar 2;5:8639. doi: 10.1038/srep08639. PubMed
RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism. Garcia-Mariscal A, Peyrollier K, Basse A, Pedersen E, Ruhl R, van Hengel J, Brakebusch C. Small GTPases. 2016 Oct 18:1-12. PubMed
G protein-coupled estrogen receptor 1 (GPER1)/GPR30 increases ERK1/2 activity through PDZ motif-dependent and -independent mechanisms. Gonzalez de Valdivia E, Broselid S, Kahn R, Olde B, Leeb-Lundberg LMF. J Biol Chem. 2017 Jun 16;292(24):9932-9943. doi: 10.1074/jbc.M116.765875. Epub 2017 Apr 27. PubMed
Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm. Younan P, Iampietro M, Nishida A, Ramanathan P, Santos RI, Dutta M, Lubaki NM, Koup RA, Katze MG, Bukreyev A. MBio. 2017 Sep 26;8(5). pii: mBio.00845-17. doi: 10.1128/mBio.00845-17. PubMed
Src-family kinases negatively regulate NFAT signaling in resting human T cells. Baer A, Colon-Moran W, Xiang J, Stapleton JT, Bhattarai N. PLoS One. 2017 Oct 26;12(10):e0187123. doi: 10.1371/journal.pone.0187123. eCollection 2017. PubMed
CC-401 Promotes beta-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition. Abdolazimi Y, Zhao Z, Lee S, Xu H, Allegretti P, Horton TM, Yeh B, Moeller HP, Nichols RJ, McCutcheon D, Shalizi A, Smith M, Armstrong NA, Annes JP. Endocrinology. 2018 Sep 1;159(9):3143-3157. doi: 10.1210/en.2018-00083. PubMed
A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression. Kycia I, Wolford BN, Huyghe JR, Fuchsberger C, Vadlamudi S, Kursawe R, Welch RP, Albanus RD, Uyar A, Khetan S, Lawlor N, Bolisetty M, Mathur A, Kuusisto J, Laakso M, Ucar D, Mohlke KL, Boehnke M, Collins FS, Parker SCJ, Stitzel ML. Am J Hum Genet. 2018 Apr 5;102(4):620-635. doi: 10.1016/j.ajhg.2018.02.020. PubMed
Characterization of the effects of immunomodulatory drug fingolimod (FTY720) on human T cell receptor signaling pathways. Baer A, Colon-Moran W, Bhattarai N. Sci Rep. 2018 Jul 19;8(1):10910. doi: 10.1038/s41598-018-29355-0. PubMed
NHA2 promotes cyst development in an in vitro model of polycystic kidney disease. Prasad H, Dang DK, Kondapalli KC, Natarajan N, Cebotaru V, Rao R. J Physiol. 2019 Jan;597(2):499-519. doi: 10.1113/JP276796. Epub 2018 Oct 17. PubMed
Osmolarity and calcium regulate connective tissue growth factor (CTGF/CCN2) expression in nucleus pulposus cells. Lin W, Shi C, Wang W, Wu H, Yang C, Wang A, Shen X, Tian Y, Cao P, Yuan W. Gene. 2019 Jul 1;704:15-24. doi: 10.1016/j.gene.2019.04.020. Epub 2019 Apr 6. PubMed
Lithium chloride corrects weakness and myopathology in a preclinical model of LGMD1D. Findlay AR, Bengoechea R, Pittman SK, Chou TF, True HL, Weihl CC. Neurol Genet. 2019 Apr 18;5(2):e318. doi: 10.1212/NXG.0000000000000318. eCollection 2019 Apr. PubMed
Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes. Rodriguez-Fdez S, Fernandez-Nevado L, Lorenzo-Martin LF, Bustelo XR. Cells. 2020 Mar 4;9(3). pii: cells9030609. doi: 10.3390/cells9030609. PubMed
Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ss-catenin. Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, Yang Y. Elife. 2020 Mar 18;9. pii: 52779. doi: 10.7554/eLife.52779. PubMed
CTRP9 Mediates Protective Effects in Cardiomyocytes via AMPK- and Adiponectin Receptor-Mediated Induction of Anti-Oxidant Response. Niemann B, Li L, Siegler D, Siegler BH, Knapp F, Hanna J, Aslam M, Kracht M, Schulz R, Rohrbach S. Cells. 2020 May 15;9(5). pii: cells9051229. doi: 10.3390/cells9051229. PubMed

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