RelA cFlag pcDNA3 Citations (35)

Originally described in: A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation.
Sanjabi S, Williams KJ, Saccani S, Zhou L, Hoffmann A, Ghosh G, Gerondakis S, Natoli G, Smale ST Genes Dev. 2005 Sep 15. 19(18):2138-51. PubMed Journal

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Articles Citing RelA cFlag pcDNA3

Articles
The p65 subunit of NF-kappaB binds to PGC-1alpha, linking inflammation and metabolic disturbances in cardiac cells. Alvarez-Guardia D, Palomer X, Coll T, Davidson MM, Chan TO, Feldman AM, Laguna JC, Vázquez-Carrera M. Cardiovasc Res. 2010 Aug 1. 87(3):449-58. PubMed
TNF-alpha and IL-1beta promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc. Wang J, Markova D, Anderson DG, Zheng Z, Shapiro IM, Risbud MV. J Biol Chem. 2011 Nov 18;286(46):39738-49. doi: 10.1074/jbc.M111.264549. Epub 2011 Sep 23. PubMed
Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells. Ghoreschi K, Bruck J, Kellerer C, Deng C, Peng H, Rothfuss O, Hussain RZ, Gocke AR, Respa A, Glocova I, Valtcheva N, Alexander E, Feil S, Feil R, Schulze-Osthoff K, Rupec RA, Lovett-Racke AE, Dringen R, Racke MK, Rocken M. J Exp Med. 2011 Oct 24;208(11):2291-303. doi: 10.1084/jem.20100977. Epub 2011 Oct 10. PubMed
Bone morphogenetic protein signaling in vascular disease: anti-inflammatory action through myocardin-related transcription factor A. Wang D, Prakash J, Nguyen P, Davis-Dusenbery BN, Hill NS, Layne MD, Hata A, Lagna G. J Biol Chem. 2012 Aug 10;287(33):28067-77. doi: 10.1074/jbc.M112.379487. Epub 2012 Jun 20. PubMed
Tumor necrosis factor alpha- and interleukin-1beta-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1. Wang J, Tian Y, Phillips KL, Chiverton N, Haddock G, Bunning RA, Cross AK, Shapiro IM, Le Maitre CL, Risbud MV. Arthritis Rheum. 2013 Mar;65(3):832-42. doi: 10.1002/art.37819. PubMed
Regulation of anoikis by deleted in breast cancer-1 (DBC1) through NF-kappaB. Park SH, Riley P 4th, Frisch SM. Apoptosis. 2013 Aug;18(8):949-62. doi: 10.1007/s10495-013-0847-1. PubMed
Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration. Wang H, Tian Y, Wang J, Phillips KL, Binch AL, Dunn S, Cross A, Chiverton N, Zheng Z, Shapiro IM, Le Maitre CL, Risbud MV. J Biol Chem. 2013 Jun 7;288(23):16761-74. doi: 10.1074/jbc.M112.446633. Epub 2013 Apr 15. PubMed
Modulation by Syk of Bcl-2, calcium and the calpain-calpastatin proteolytic system in human breast cancer cells. Fei B, Yu S, Geahlen RL. Biochim Biophys Acta. 2013 Oct;1833(10):2153-64. doi: 10.1016/j.bbamcr.2013.05.010. Epub 2013 May 16. PubMed
Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-kappaB (NF-kappaB): a feed-forward loop for systemic and vascular inflammation. Leslie KL, Song GJ, Barrick S, Wehbi VL, Vilardaga JP, Bauer PM, Bisello A. J Biol Chem. 2013 Dec 20;288(51):36426-36. doi: 10.1074/jbc.M113.483339. Epub 2013 Nov 6. PubMed
IkappaB kinase gamma/nuclear factor-kappaB-essential modulator (IKKgamma/NEMO) facilitates RhoA GTPase activation, which, in turn, activates Rho-associated KINASE (ROCK) to phosphorylate IKKbeta in response to transforming growth factor (TGF)-beta1. Kim HJ, Kim JG, Moon MY, Park SH, Park JB. J Biol Chem. 2014 Jan 17;289(3):1429-40. doi: 10.1074/jbc.M113.520130. Epub 2013 Nov 16. PubMed
Nuclear factor-kappaB is a common upstream signal for growth differentiation factor-5 expression in brown adipocytes exposed to pro-inflammatory cytokines and palmitate. Hinoi E, Iezaki T, Ozaki K, Yoneda Y. Biochem Biophys Res Commun. 2014 Oct 3;452(4):974-9. doi: 10.1016/j.bbrc.2014.09.022. Epub 2014 Sep 16. PubMed
Prolyl-4-hydroxylase domain protein 2 controls NF-kappaB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus. Li J, Yuan W, Jiang S, Ye W, Yang H, Shapiro IM, Risbud MV. J Biol Chem. 2015 Mar 13;290(11):7195-207. doi: 10.1074/jbc.M114.611483. Epub 2015 Jan 29. PubMed
Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer. Bagnall J, Boddington C, Boyd J, Brignall R, Rowe W, Jones NA, Schmidt L, Spiller DG, White MR, Paszek P. Integr Biol (Camb). 2015 Jun 8;7(6):713-25. doi: 10.1039/c5ib00067j. Epub 2015 May 20. PubMed
PACS-2 mediates the ATM and NF-kappaB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Barroso-Gonzalez J, Auclair S, Luan S, Thomas L, Atkins KM, Aslan JE, Thomas LL, Zhao J, Zhao Y, Thomas G. Cell Death Differ. 2016 Mar 4. doi: 10.1038/cdd.2016.23. PubMed
Transcriptional Modulator Ifrd1 Regulates Osteoclast Differentiation through Enhancing the NF-kappaB/NFATc1 Pathway. Iezaki T, Fukasawa K, Park G, Horie T, Kanayama T, Ozaki K, Onishi Y, Takahata Y, Nakamura Y, Takarada T, Yoneda Y, Nakamura T, Vacher J, Hinoi E. Mol Cell Biol. 2016 Sep 12;36(19):2451-63. doi: 10.1128/MCB.01075-15. Print 2016 Oct 1. PubMed
RNA Sequencing Reveals a Role of TonEBP Transcription Factor in Regulation of Pro-inflammatory Genes in Response to Hyperosmolarity in Healthy Nucleus Pulposus Cells: A HOMEOSTATIC RESPONSE? Johnson ZI, Shapiro IM, Risbud MV. J Biol Chem. 2016 Dec 23;291(52):26686-26697. doi: 10.1074/jbc.M116.757732. Epub 2016 Nov 8. PubMed
RTA Occupancy of the Origin of Lytic Replication during Murine Gammaherpesvirus 68 Reactivation from B Cell Latency. Santana AL, Oldenburg DG, Kirillov V, Malik L, Dong Q, Sinayev R, Marcu KB, White DW, Krug LT. Pathogens. 2017 Feb 16;6(1). pii: E9. doi: 10.3390/pathogens6010009. PubMed
Reduction of Ether-Type Glycerophospholipids, Plasmalogens, by NF-kappaB Signal Leading to Microglial Activation. Hossain MS, Abe Y, Ali F, Youssef M, Honsho M, Fujiki Y, Katafuchi T. J Neurosci. 2017 Apr 12;37(15):4074-4092. doi: 10.1523/JNEUROSCI.3941-15.2017. Epub 2017 Mar 14. PubMed
Antipsychotic-induced Hdac2 transcription via NF-kappaB leads to synaptic and cognitive side effects. Ibi D, de la Fuente Revenga M, Kezunovic N, Muguruza C, Saunders JM, Gaitonde SA, Moreno JL, Ijaz MK, Santosh V, Kozlenkov A, Holloway T, Seto J, Garcia-Bea A, Kurita M, Mosley GE, Jiang Y, Christoffel DJ, Callado LF, Russo SJ, Dracheva S, Lopez-Gimenez JF, Ge Y, Escalante CR, Meana JJ, Akbarian S, Huntley GW, Gonzalez-Maeso J. Nat Neurosci. 2017 Sep;20(9):1247-1259. doi: 10.1038/nn.4616. Epub 2017 Aug 7. PubMed
Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages. Kanemaru H, Yamane F, Fukushima K, Matsuki T, Kawasaki T, Ebina I, Kuniyoshi K, Tanaka H, Maruyama K, Maeda K, Satoh T, Akira S. Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7331-E7340. doi: 10.1073/pnas.1708598114. Epub 2017 Aug 14. PubMed
TNF-alpha promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells. Johnson ZI, Doolittle AC, Snuggs JW, Shapiro IM, Le Maitre CL, Risbud MV. J Biol Chem. 2017 Oct 20;292(42):17561-17575. doi: 10.1074/jbc.M117.790378. Epub 2017 Aug 25. PubMed
A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib. Ebelt ND, Kaoud TS, Edupuganti R, Van Ravenstein S, Dalby KN, Van Den Berg CL. Oncotarget. 2017 Aug 24;8(62):104894-104912. doi: 10.18632/oncotarget.20581. eCollection 2017 Dec 1. PubMed
BATF2 activates DUSP2 gene expression and up-regulates NF-kappaB activity via phospho-STAT3 dephosphorylation. Kanemaru H, Yamane F, Tanaka H, Maeda K, Satoh T, Akira S. Int Immunol. 2018 May 24;30(6):255-265. doi: 10.1093/intimm/dxy023. PubMed
Alleviation of Murine Osteoarthritis by Cartilage-Specific Deletion of IkappaBzeta. Choi MC, MaruYama T, Chun CH, Park Y. Arthritis Rheumatol. 2018 Sep;70(9):1440-1449. doi: 10.1002/art.40514. Epub 2018 Jul 25. PubMed
A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD(+) Decline. Tarrago MG, Chini CCS, Kanamori KS, Warner GM, Caride A, de Oliveira GC, Rud M, Samani A, Hein KZ, Huang R, Jurk D, Cho DS, Boslett JJ, Miller JD, Zweier JL, Passos JF, Doles JD, Becherer DJ, Chini EN. Cell Metab. 2018 May 1;27(5):1081-1095.e10. doi: 10.1016/j.cmet.2018.03.016. PubMed
Andalucin from Artemisia lannta suppresses the neuroinflammation via the promotion of Nrf2-mediated HO-1 levels by blocking the p65-p300 interaction in LPS-activated BV2 microglia. Wang X, Gai YN, Li BB, Huang LL. Phytomedicine. 2018 Dec 1;51:226-232. doi: 10.1016/j.phymed.2018.06.014. Epub 2018 Jun 23. PubMed
Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Wheeler MA, Jaronen M, Covacu R, Zandee SEJ, Scalisi G, Rothhammer V, Tjon EC, Chao CC, Kenison JE, Blain M, Rao VTS, Hewson P, Barroso A, Gutierrez-Vazquez C, Prat A, Antel JP, Hauser R, Quintana FJ. Cell. 2019 Jan 24;176(3):581-596.e18. doi: 10.1016/j.cell.2018.12.012. Epub 2019 Jan 17. PubMed
Elevated Thrombospondin 2 Contributes to Delayed Wound Healing in Diabetes. Kunkemoeller B, Bancroft T, Xing H, Morris AH, Luciano AK, Wu J, Fernandez-Hernando C, Kyriakides TR. Diabetes. 2019 Oct;68(10):2016-2023. doi: 10.2337/db18-1001. Epub 2019 Aug 7. PubMed
Assaying Homodimers of NF-kappaB in Live Single Cells. Martin EW, Chakraborty S, Presman DM, Tomassoni Ardori F, Oh KS, Kaileh M, Tessarollo L, Sung MH. Front Immunol. 2019 Nov 7;10:2609. doi: 10.3389/fimmu.2019.02609. eCollection 2019. PubMed
Integrative analysis suggests cell type-specific decoding of NF-kappaB dynamics. Martin EW, Pacholewska A, Patel H, Dashora H, Sung MH. Sci Signal. 2020 Feb 25;13(620). pii: 13/620/eaax7195. doi: 10.1126/scisignal.aax7195. PubMed
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy. Gao Y, Nihira NT, Bu X, Chu C, Zhang J, Kolodziejczyk A, Fan Y, Chan NT, Ma L, Liu J, Wang D, Dai X, Liu H, Ono M, Nakanishi A, Inuzuka H, North BJ, Huang YH, Sharma S, Geng Y, Xu W, Liu XS, Li L, Miki Y, Sicinski P, Freeman GJ, Wei W. Nat Cell Biol. 2020 Sep;22(9):1064-1075. doi: 10.1038/s41556-020-0562-4. Epub 2020 Aug 24. PubMed
Macrophage regulator of G-protein signaling 12 contributes to inflammatory pain hypersensitivity. Yuan G, Yang S, Gautam M, Luo W, Yang S. Ann Transl Med. 2021 Mar;9(6):448. doi: 10.21037/atm-20-5729. PubMed
NF-kappaB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1. Shen Y, Endale M, Wang W, Morris AR, Francey LJ, Harold RL, Hammers DW, Huo Z, Partch CL, Hogenesch JB, Wu ZH, Liu AC. PLoS Genet. 2021 Nov 22;17(11):e1009933. doi: 10.1371/journal.pgen.1009933. eCollection 2021 Nov. PubMed
Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation. Thevkar-Nagesh P, Habault J, Voisin M, Ruff SE, Ha S, Ruoff R, Chen X, Rawal S, Zahr T, Szabo G, Rogatsky I, Fisher EA, Garabedian MJ. PLoS One. 2022 Sep 2;17(9):e0272986. doi: 10.1371/journal.pone.0272986. eCollection 2022. PubMed
Loss of PARP7 Increases Type I Interferon Signaling in EO771 Breast Cancer Cells and Prevents Mammary Tumor Growth by Increasing Antitumor Immunity. Rasmussen M, Alvik K, Kannen V, Olafsen NE, Erlingsson LAM, Grimaldi G, Takaoka A, Grant DM, Matthews J. Cancers (Basel). 2023 Jul 20;15(14):3689. doi: 10.3390/cancers15143689. PubMed

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