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LeGO-iG2 Citations (32)

Originally described in: A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis.
Weber K, Bartsch U, Stocking C, Fehse B Mol Ther. 2008 Apr . 16(4):698-706. PubMed Journal

Articles Citing LeGO-iG2

Articles
The activity of the anti-apoptotic fragment generated by the caspase-3/p120 RasGAP stress-sensing module displays strict Akt isoform specificity. Vanli G, Peltzer N, Dubuis G, Widmann C. Cell Signal. 2014 Dec;26(12):2992-7. doi: 10.1016/j.cellsig.2014.09.009. Epub 2014 Sep 22. PubMed
The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling. Ochodnicka-Mackovicova K, Bahjat M, Maas C, van der Veen A, Bloedjes TA, de Bruin AM, van Andel H, Schrader CE, Hendriks RW, Verhoeyen E, Bende RJ, van Noesel CJ, Guikema JE. J Immunol. 2016 Oct 1;197(7):2918-29. doi: 10.4049/jimmunol.1501989. Epub 2016 Aug 24. PubMed
Generation of functional endothelial cells with progenitor-like features from murine induced pluripotent stem cells. Kachamakova-Trojanowska N, Nowak W, Szade K, Stepniewski J, Bukowska-Strakova K, Zukowska M, Taha H, Chmura-Skirlinska A, Beilharz M, Dulak J, Jozkowicz A. Vascul Pharmacol. 2016 Nov;86:94-108. doi: 10.1016/j.vph.2016.07.008. Epub 2016 Aug 25. PubMed
A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome. Hein LK, Apaja PM, Hattersley K, Grose RH, Xie J, Proud CG, Sargeant TJ. Biochim Biophys Acta. 2017 Jun 19;1864(10):1554-1565. doi: 10.1016/j.bbamcr.2017.06.011. PubMed
Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. Schell JC, Wisidagama DR, Bensard C, Zhao H, Wei P, Tanner J, Flores A, Mohlman J, Sorensen LK, Earl CS, Olson KA, Miao R, Waller TC, Delker D, Kanth P, Jiang L, DeBerardinis RJ, Bronner MP, Li DY, Cox JE, Christofk HR, Lowry WE, Thummel CS, Rutter J. Nat Cell Biol. 2017 Sep;19(9):1027-1036. doi: 10.1038/ncb3593. Epub 2017 Aug 14. PubMed
Thrombospondin Type 1 Domain-Containing 7A Localizes to the Slit Diaphragm and Stabilizes Membrane Dynamics of Fully Differentiated Podocytes. Herwig J, Skuza S, Sachs W, Sachs M, Failla AV, Rune G, Meyer TN, Fester L, Meyer-Schwesinger C. J Am Soc Nephrol. 2019 May;30(5):824-839. doi: 10.1681/ASN.2018090941. Epub 2019 Apr 10. PubMed
Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, Metzner M, Kennedy A, Amstislavskiy V, Risch T, Bhayadia R, Samulowski D, Hernandez DC, Stoilova B, Iotchkova V, Oppermann U, Scheer C, Yoshida K, Schwarzer A, Taub JW, Crispino JD, Weiss MJ, Hayashi Y, Taga T, Ito E, Ogawa S, Reinhardt D, Yaspo ML, Campbell PJ, Roberts I, Constantinescu SN, Vyas P, Heckl D, Klusmann JH. Cancer Cell. 2019 Aug 12;36(2):123-138.e10. doi: 10.1016/j.ccell.2019.06.007. Epub 2019 Jul 11. PubMed

Associated Plasmids
Promoter demethylation of the asparagine synthetase gene is required for ATF4-dependent adaptation to asparagine depletion. Jiang J, Srivastava S, Seim G, Pavlova NN, King B, Zou L, Zhang C, Zhong M, Feng H, Kapur R, Wek RC, Fan J, Zhang J. J Biol Chem. 2019 Dec 6;294(49):18674-18684. doi: 10.1074/jbc.RA119.010447. Epub 2019 Oct 28. PubMed
Evaluation of reference genes for quantitative real-time PCR in Wharton's Jelly-derived mesenchymal stem cells after lentiviral transduction and differentiation. Borkowska P, Zielinska A, Paul-Samojedny M, Stojko R, Kowalski J. Mol Biol Rep. 2020 Feb;47(2):1107-1115. doi: 10.1007/s11033-019-05207-6. Epub 2019 Nov 28. PubMed
Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent. Cloux AJ, Aubry D, Heulot M, Widmann C, ElMokh O, Piacente F, Cea M, Nencioni A, Bellotti A, Bouzourene K, Pellegrin M, Mazzolai L, Duchosal MA, Nahimana A. Oncotarget. 2019 Nov 19;10(62):6723-6738. doi: 10.18632/oncotarget.27336. eCollection 2019 Nov 19. PubMed
Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D. Sayitoglu EC, Georgoudaki AM, Chrobok M, Ozkazanc D, Josey BJ, Arif M, Kusser K, Hartman M, Chinn TM, Potens R, Pamukcu C, Krueger R, Zhang C, Mardinoglu A, Alici E, Temple HT, Sutlu T, Duru AD. Front Immunol. 2020 Jan 28;11:40. doi: 10.3389/fimmu.2020.00040. eCollection 2020. PubMed
A High-Throughput HIV-1 Drug Screening Platform, Based on Lentiviral Vectors and Compatible with Biosafety Level-1. Ellinger B, Pohlmann D, Woens J, Jakel FM, Reinshagen J, Stocking C, Prassolov VS, Fehse B, Riecken K. Viruses. 2020 May 25;12(5). pii: v12050580. doi: 10.3390/v12050580. PubMed

Associated Plasmids
Functional Heterogeneity of Protein Kinase A Activation in Multipotent Stromal Cells. Tyurin-Kuzmin PA, Karagyaur MN, Kulebyakin KY, Dyikanov DT, Chechekhin VI, Ivanova AM, Skryabina MN, Arbatskiy MS, Sysoeva VY, Kalinina NI, Tkachuk VA. Int J Mol Sci. 2020 Jun 22;21(12). pii: ijms21124442. doi: 10.3390/ijms21124442. PubMed
Dynamic palmitoylation events following T-cell receptor signaling. Morrison E, Wegner T, Zucchetti AE, Alvaro-Benito M, Zheng A, Kliche S, Krause E, Brugger B, Hivroz C, Freund C. Commun Biol. 2020 Jul 10;3(1):368. doi: 10.1038/s42003-020-1063-5. PubMed
Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation. Cuello F, Knaust AE, Saleem U, Loos M, Raabe J, Mosqueira D, Laufer S, Schweizer M, van der Kraak P, Flenner F, Ulmer BM, Braren I, Yin X, Theofilatos K, Ruiz-Orera J, Patone G, Klampe B, Schulze T, Piasecki A, Pinto Y, Vink A, Hubner N, Harding S, Mayr M, Denning C, Eschenhagen T, Hansen A. EMBO Mol Med. 2021 Jun 7;13(6):e13074. doi: 10.15252/emmm.202013074. Epub 2021 May 16. PubMed
Context-Specific Osteogenic Potential of Mesenchymal Stem Cells. Kostina A, Lobov A, Semenova D, Kiselev A, Klausen P, Malashicheva A. Biomedicines. 2021 Jun 12;9(6). pii: biomedicines9060673. doi: 10.3390/biomedicines9060673. PubMed
Synergistic Effect of the Long-Term Overexpression of Bcl-2 and BDNF Lentiviral in Cell Protecting against Death and Generating TH Positive and CHAT Positive Cells from MSC. Borkowska P, Zielinska A, Paul-Samojedny M, Stojko R, Kowalski J. Int J Mol Sci. 2021 Jun 30;22(13). pii: ijms22137086. doi: 10.3390/ijms22137086. PubMed
Dual-Specificity Phosphatase 9 Regulates Cellular Proliferation and Predicts Recurrence After Surgery in Hepatocellular Carcinoma. Chen K, Gorgen A, Ding A, Du L, Jiang K, Ding Y, Sapisochin G, Ghanekar A. Hepatol Commun. 2021 Mar 11;5(7):1310-1328. doi: 10.1002/hep4.1701. eCollection 2021 Jul. PubMed
LATE-a novel sensitive cell-based assay for the study of CRISPR/Cas9-related long-term adverse treatment effects. Glow D, Meyer S, Garcia Roldan I, Akingunsade LM, Riecken K, Fehse B. Mol Ther Methods Clin Dev. 2021 Jul 29;22:249-262. doi: 10.1016/j.omtm.2021.07.004. eCollection 2021 Sep 10. PubMed
Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest. Czarnek M, Sarad K, Karas A, Kochan J, Bereta J. Mol Ther Nucleic Acids. 2021 Sep 15;26:711-731. doi: 10.1016/j.omtn.2021.09.004. eCollection 2021 Dec 3. PubMed
Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore. Trofimenko E, Grasso G, Heulot M, Chevalier N, Deriu MA, Dubuis G, Arribat Y, Serulla M, Michel S, Vantomme G, Ory F, Dam LC, Puyal J, Amati F, Luthi A, Danani A, Widmann C. Elife. 2021 Oct 29;10. pii: 69832. doi: 10.7554/eLife.69832. PubMed
CRISPR-to-Kill (C2K)-Employing the Bacterial Immune System to Kill Cancer Cells. Glow D, Maire CL, Schwarze LI, Lamszus K, Fehse B. Cancers (Basel). 2021 Dec 15;13(24). pii: cancers13246306. doi: 10.3390/cancers13246306. PubMed
Regulation of Glucose Transport in Adipocytes by Interleukin-4. Michurina S, Stafeev I, Beloglazova I, Zubkova E, Mamontova E, Kopylov A, Shevchenko E, Menshikov M, Parfyonova Y. J Interferon Cytokine Res. 2022 Mar;42(3):127-136. doi: 10.1089/jir.2021.0213. PubMed
Impact of p53 knockdown on protein dataset of HaCaT cells. Romashin DD, Rusanov AL, Kozhin PM, Karagyaur MN, Tikhonova OV, Zgoda VG, Luzgina NG. Data Brief. 2022 May 15;42:108274. doi: 10.1016/j.dib.2022.108274. eCollection 2022 Jun. PubMed
Survival and Neurogenesis-Promoting Effects of the Co-Overexpression of BCLXL and BDNF Genes on Wharton's Jelly-Derived Mesenchymal Stem Cells. Borkowska P, Morys J, Zielinska A, Sadlocha M, Kowalski J. Life (Basel). 2022 Sep 9;12(9):1406. doi: 10.3390/life12091406. PubMed
Asparagine bioavailability regulates the translation of MYC oncogene. Srivastava S, Jiang J, Misra J, Seim G, Staschke KA, Zhong M, Zhou L, Liu Y, Chen C, Dave U, Kapur R, Batra S, Zhang C, Zhou J, Fan J, Wek RC, Zhang J. Oncogene. 2022 Oct;41(44):4855-4865. doi: 10.1038/s41388-022-02474-9. Epub 2022 Oct 1. PubMed
A MYC-ZNF148-ID1/3 regulatory axis modulating cancer stem cell traits in aggressive breast cancer. Kim M, Singh M, Lee BK, Hibbs M, Richardson K, Ellies L, Wintle L, Stuart LM, Wang JY, Voon DC, Blancafort P, Wang J, Kim J, Leedman PJ, Woo AJ. Oncogenesis. 2022 Oct 7;11(1):60. doi: 10.1038/s41389-022-00435-1. PubMed
Asparagine starvation suppresses histone demethylation through iron depletion. Jiang J, Srivastava S, Liu S, Seim G, Claude R, Zhong M, Cao S, Dave U, Kapur R, Mosley AL, Zhang C, Wan J, Fan J, Zhang J. iScience. 2023 Mar 16;26(4):106425. doi: 10.1016/j.isci.2023.106425. eCollection 2023 Apr 21. PubMed
Effects of the Co-Overexpression of the BCL and BDNF Genes on the Gamma-Aminobutyric Acid-Ergic Differentiation of Wharton's-Jelly-Derived Mesenchymal Stem Cells. Borkowska P, Morys J, Zielinska A, Kowalski J. Biomedicines. 2023 Jun 18;11(6):1751. doi: 10.3390/biomedicines11061751. PubMed
Early protective effect of a ("pan") coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration. Abdelaziz MO, Raftery MJ, Weihs J, Bielawski O, Edel R, Koppke J, Vladimirova D, Adler JM, Firsching T, Voss A, Gruber AD, Hummel LV, Fernandez Munoz I, Muller-Marquardt F, Willimsky G, Elleboudy NS, Trimpert J, Schonrich G. Front Immunol. 2023 Jul 13;14:1166765. doi: 10.3389/fimmu.2023.1166765. eCollection 2023. PubMed
Endothelial Cell Replacement of Human Veins, Modeling Vascular Repair and Endothelial Cell Chimerism. Tejeda-Mora H, den Hartog Y, Schurink IJ, Verstegen MMA, de Jonge J, van den Hoogen MWF, Baan CC, Minnee RC, Hoogduijn MJ, van der Laan LJW, Willemse J. Stem Cells Dev. 2024 Jan;33(1-2):27-42. doi: 10.1089/scd.2023.0142. Epub 2023 Dec 27. PubMed
Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers. Jessen M, Gertzmann D, Liss F, Zenk F, Bahner L, Schoffler V, Schulte C, Maric HM, Ade CP, von Eyss B, Gaubatz S. Oncogene. 2024 Feb;43(8):578-593. doi: 10.1038/s41388-023-02926-w. Epub 2024 Jan 5. PubMed

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