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FLAG-HSF1 Citations (9)

Originally described in: Regulation of molecular chaperone gene transcription involves the serine phosphorylation, 14-3-3 epsilon binding, and cytoplasmic sequestration of heat shock factor 1.
Wang X, Grammatikakis N, Siganou A, Calderwood SK Mol Cell Biol. 2003 Sep;23(17):6013-26.
PubMed Journal

Articles Citing FLAG-HSF1

Articles
Hyperthermia stress activates heat shock protein expression via propyl isomerase 1 regulation with heat shock factor 1. Wang HY, Fu JC, Lee YC, Lu PJ. Mol Cell Biol. 2013 Dec;33(24):4889-99. doi: 10.1128/MCB.00475-13. Epub 2013 Oct 14. PubMed
Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells. Carpenter RL, Paw I, Dewhirst MW, Lo HW. Oncogene. 2015 Jan 29;34(5):546-57. doi: 10.1038/onc.2013.582. Epub 2014 Jan 27. PubMed
Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases. Dayalan Naidu S, Sutherland C, Zhang Y, Risco A, de la Vega L, Caunt CJ, Hastie CJ, Lamont DJ, Torrente L, Chowdhry S, Benjamin IJ, Keyse SM, Cuenda A, Dinkova-Kostova AT. Mol Cell Biol. 2016 Aug 26;36(18):2403-17. doi: 10.1128/MCB.00292-16. Print 2016 Sep 15. PubMed
Interaction of a Novel Chaperone PhLP2A With the Heat Shock Protein Hsp90. Krzemien-Ojak L, Goral A, Joachimiak E, Filipek A, Fabczak H. J Cell Biochem. 2017 Feb;118(2):420-429. doi: 10.1002/jcb.25669. Epub 2016 Oct 17. PubMed
Combined inhibition of AKT and HSF1 suppresses breast cancer stem cells and tumor growth. Carpenter RL, Sirkisoon S, Zhu D, Rimkus T, Harrison A, Anderson A, Paw I, Qasem S, Xing F, Liu Y, Chan M, Metheny-Barlow L, Pasche BC, Debinski W, Watabe K, Lo HW. Oncotarget. 2017 May 22;8(43):73947-73963. doi: 10.18632/oncotarget.18166. eCollection 2017 Sep 26. PubMed
HSF1 Regulates Mevalonate and Cholesterol Biosynthesis Pathways. Kang H, Oh T, Bahk YY, Kim GH, Kan SY, Shin DH, Kim JH, Lim JH. Cancers (Basel). 2019 Sep 13;11(9). pii: cancers11091363. doi: 10.3390/cancers11091363. PubMed
AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation. Lu WC, Omari R, Ray H, Wang J, Williams I, Jacobs C, Hockaden N, Bochman ML, Carpenter RL. FEBS J. 2022 Jul;289(13):3876-3893. doi: 10.1111/febs.16375. Epub 2022 Feb 11. PubMed
ErbB2 promotes breast cancer metastatic potential via HSF1/LDHA axis-mediated glycolysis. He L, Lv S, Ma X, Jiang S, Zhou F, Zhang Y, Yu R, Zhao Y. Med Oncol. 2022 Jan 29;39(4):45. doi: 10.1007/s12032-021-01641-4. PubMed
Human herpesvirus 6A nuclear matrix protein U37 interacts with heat shock transcription factor 1 and activates the heat shock response. Huang JR, Arii J, Hirai M, Nishimura M, Mori Y. J Virol. 2023 Sep 28;97(9):e0071823. doi: 10.1128/jvi.00718-23. Epub 2023 Sep 6. PubMed

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