pDONR223_NRAS_p.G12C Citations (2)
Originally described in: Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles.Kim E, Ilic N, Shrestha Y, Zou L, Kamburov A, Zhu C, Yang X, Lubonja R, Tran N, Nguyen C, Lawrence MS, Piccioni F, Bagul M, Doench JG, Chouinard CR, Wu X, Hogstrom L, Natoli T, Tamayo P, Horn H, Corsello SM, Lage K, Root DE, Subramanian A, Golub TR, Getz G, Boehm JS, Hahn WC Cancer Discov. 2016 Jul;6(7):714-26. doi: 10.1158/2159-8290.CD-16-0160. Epub 2016 May 4. PubMed Journal
Articles Citing pDONR223_NRAS_p.G12C
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Designed active-site library reveals thousands of functional GFP variants.
Weinstein JY, Marti-Gomez C, Lipsh-Sokolik R, Hoch SY, Liebermann D, Nevo R, Weissman H, Petrovich-Kopitman E, Margulies D, Ivankov D, McCandlish DM, Fleishman SJ.
Nat Commun. 2023 May 20;14(1):2890. doi: 10.1038/s41467-023-38099-z.
PubMed
Associated Plasmids |
| Sotorasib is a pan-RASG12C inhibitor capable of driving clinical response in NRASG12C cancers. Rubinson DA, Tanaka N, Fece de la Cruz F, Kapner KS, Rosenthal MH, Norden BL, Barnes H, Ehnstrom S, Morales-Giron AA, Brais LK, Lemke CT, Aguirre AJ, Corcoran RB. Cancer Discov. 2024 Jan 18. doi: 10.1158/2159-8290.CD-23-1138. PubMed |
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