Xin Chen Lab Plasmids


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Title Authors Publication
Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma. Tschaharganeh DF, Chen X, Latzko P, Malz M, Gaida MM, Felix K, Ladu S, Singer S, Pinna F, Gretz N, Sticht C, Tomasi ML, Delogu S, Evert M, Fan B, Ribback S, Jiang L, Brozzetti S, Bergmann F, Dombrowski F, Schirmacher P, Calvisi DF, Breuhahn K Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16.
Cholangiocarcinomas can originate from hepatocytes in mice. Fan B, Malato Y, Calvisi DF, Naqvi S, Razumilava N, Ribback S, Gores GJ, Dombrowski F, Evert M, Chen X, Willenbring H J Clin Invest. 2012 Aug 1;122(8):2911-5. doi: 10.1172/JCI63212. Epub 2012 Jul 17.
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma. Calvisi DF, Wang C, Ho C, Ladu S, Lee SA, Mattu S, Destefanis G, Delogu S, Zimmermann A, Ericsson J, Brozzetti S, Staniscia T, Chen X, Dombrowski F, Evert M Gastroenterology. 2011 Mar;140(3):1071-83. Epub 2010 Dec 11.
Bmi1 functions as an oncogene independent of Ink4A/Arf repression in hepatic carcinogenesis. Xu CR, Lee S, Ho C, Bommi P, Huang SA, Cheung ST, Dimri GP, Chen X Mol Cancer Res. 2009 Dec;7(12):1937-45. Epub 2009 Nov 24.
Distinct pathways of genomic progression to benign and malignant tumors of the liver. Tward AD, Jones KD, Yant S, Cheung ST, Fan ST, Chen X, Kay MA, Wang R, Bishop JM Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14771-6. Epub 2007 Sep 4.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
31783 pT3-EF1a-Bmi1 Bmi1 (Homo sapiens) Mammalian Expression Xu et al Mol Cancer Res. 2009 Dec;7(12):1937-45. Epub 2009 Nov 24. pT3-EF1a BMI1 RP11-573G6.1, FLVI2/BMI1, PCGF4, RNF51
31784 pT3-EF1a-c-Met Met (Homo sapiens) Mammalian Expression Tward et al Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14771-6. Epub 2007 Sep 4. pT3-EF1a MET AUTS9, HGFR, RCCP2, c-Met
31785 pT3-N90-beta-catenin beta-catenin (Homo sapiens) Mammalian Expression Tward et al Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14771-6. Epub 2007 Sep 4. pT3-EF1a CTNNB1 OK/SW-cl.35, CTNNB, MRD19, armadillo
31786 pENTR-c-Met Met (Homo sapiens) Entry Vector Tward et al Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14771-6. Epub 2007 Sep 4. pENTR1A MET AUTS9, HGFR, RCCP2, c-Met
31787 pENTR-N90-beta-catenin beta-catenin (Homo sapiens) Entry Vector Tward et al Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14771-6. Epub 2007 Sep 4. pENTR1A
  • Tag / Fusion Protein
    • Myc (N terminal on insert)
  • CTNNB1 OK/SW-cl.35, CTNNB, MRD19, armadillo
    31789 pT3-myr-AKT-HA AKT1 (Homo sapiens) Mammalian Expression Calvisi et al Gastroenterology. 2011 Mar;140(3):1071-83. Epub 2010 Dec 11. pT3-EF1a AKT1 AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
    31790 pENTR-myr-AKT-HA AKT1 (Homo sapiens) Entry Vector Calvisi et al Gastroenterology. 2011 Mar;140(3):1071-83. Epub 2010 Dec 11. pENTR1A AKT1 AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
    46047 pT3-EF1a-NICD1 Notch1 (C-term) (Mus musculus) Mammalian Expression Fan et al J Clin Invest. 2012 Aug 1;122(8):2911-5. doi: 10.1172/JCI63212. Epub 2012 Jul 17. pT3-EF1a Notch1 RP23-306D20.12-001, 9930111A19Rik, Mis6, N1, Tan1, lin-12
    46048 pENTR-NICD1 Notch1 (C-term) (Mus musculus) Entry Vector Fan et al J Clin Invest. 2012 Aug 1;122(8):2911-5. doi: 10.1172/JCI63212. Epub 2012 Jul 17. pENTR Notch1 RP23-306D20.12-001, 9930111A19Rik, Mis6, N1, Tan1, lin-12
    46049 pT-3EF1a-Yap S127A Yes-kinase associated protein (Homo sapiens) Mammalian Expression Tschaharganeh et al Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16. pT3-EF1a YAP1 COB1, YAP, YAP2, YAP65, YKI
    46050 pENTR1A-Yap S127A Yes-kinase associated protein (Homo sapiens) Entry Vector Tschaharganeh et al Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16. pENTR YAP1 COB1, YAP, YAP2, YAP65, YKI
    46051 pT-3EF1a-HA-Jag1 Jag1 (Rattus norvegicus) Mammalian Expression Tschaharganeh et al Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16. pT3-EF1a Jag1
    46052 pENTR1A-HA-Jag1 Jag1 (Rattus norvegicus) Entry Vector Tschaharganeh et al Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16. pENTR Jag1