Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene.
Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC
Cell. 2007 Jun 15. 129(6):1065-1079. PubMed Article
Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC
Cell. 2007 Jun 15. 129(6):1065-1079. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 15263 | pBabe-GFP-IKBalpha-wt | |
| 15264 | pBabe-GFP-IKBalpha-mut (super repressor) | |
| 15265 | pBabe-Neo-Flag-IKBKE | |
| 15266 | pBabe-Neo-Myr-Flag-AKT1 | |
| 15267 | pBabe-Neo-Myr-Flag-IKBKE | |
| 15268 | pBabe-Puro-MEK-DD | |
| 15269 | pBabe-Puro-BRAF-V600E | Retroviral expression of BRAF V600E (the V600E mutation has been found in cancer patients, confers increased kinase activity, and is transforming) |
| 15270 | pBabe-Puro-cRAF-W22 | |
| 15290 | pBabe-Puro-IKBalpha-wt | |
| 15291 | pBabe-Puro-IKBalpha-mut (super repressor) | |
| 15292 | pBabe-Puro-Flag-IKBKE | |
| 15293 | pBabe-Puro-Myr-Flag-IKBKE | |
| 15294 | pBabe-Puro-Myr-Flag-AKT1 | |
| 15301 | pENTRY-GFP | |
| 15302 | pENTRY-YFP |