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Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasion.
Wong SY, Ulrich TA, Deleyrolle LP, MacKay JL, Lin JM, Martuscello RT, Jundi MA, Reynolds BA, Kumar S
Cancer Res. 2015 Mar 15;75(6):1113-22. doi: 10.1158/0008-5472.CAN-13-3426. Epub 2015 Jan 29.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
84647pSLIK CA MLCKLentiviral expression of doxycycline-inducible constitutively active MLCK and co-expression of Venus
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84649pSLIK CA ROCK2Lentiviral expression of doxycycline-inducible constitutively active ROCK2 and co-expression of Venus
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