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WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.
Hu J, Zacharek S, He YJ, Lee H, Shumway S, Duronio RJ, Xiong Y
Genes Dev. 2008 Apr 1. 22(7):866-71.
PubMed Article

Plasmids from Article

ID Plasmid  
19904pcDNA3-FBL6-FLAG3C
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19905pCDNA3-myc3-FBW5
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19907pcDNA3-HA2-CUL4A
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19909pcDNA3-HA2-DDB1
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19911pcDNA3-HA3-TSC1
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19912pCDNA3-myc3-FBW5 delta F
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19918pcDNA3-FLAG-DDB1
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19922pcDNA3-myc3-CUL4B
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19925pcDNA3-FBL6 delta6
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