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Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons.
Liu ML, Zang T, Zou Y, Chang JC, Gibson JR, Huber KM, Zhang CL
Nat Commun. 2013;4:2183. doi: 10.1038/ncomms3183.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
90212pLNCX2-NGN2-IRES-GFPTo convert human fetal lung fibroblasts into induced cholinergic neurons (hiCN) in combination with two small molecules, forskolin and dorsomorphin.
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90213pLNCX2-NGN2-IRES-GFP-T2A-Sox11To convert human skin fibroblasts into induced cholinergic neurons (hiCN) in combination with FGF2 and two small molecules, forskolin and dorsomorphin.
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