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Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.
Koblan LW, Doman JL, Wilson C, Levy JM, Tay T, Newby GA, Maianti JP, Raguram A, Liu DR
Nat Biotechnol. 2018 May 29. pii: nbt.4172. doi: 10.1038/nbt.4172.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
112093pCMV_BE4maxC:G-to-T:A base editing
112094pCMV_AncBE4maxC:G-to-T:A base editing
112095pCMV_ABEmaxA:T-to-G:C base editing
112096pCMV_BE4max_3xHAC:G-to-T:A base editing
112097pCMV_AncBE4max_3xHAC:G-to-T:A base editing
112098pCMV_ABEmax_3xHAA:T-to-G:C base editing
112099pCMV_BE4max_P2A_GFPC:G-to-T:A base editing
112100pCMV_AncBE4max_P2A_GFPC:G-to-T:A base editing
112101pCMV_ABEmax_P2A_GFPA:T-to-G:C base editing

Antibodies from Article