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The contribution of active and passive mechanisms of 5mC and 5hmC removal in human T lymphocytes is differentiation- and activation-dependent.
Vincenzetti L, Leoni C, Chirichella M, Kwee I, Monticelli S
Eur J Immunol. 2019 Jan 30. doi: 10.1002/eji.201847967.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
124081pEF1a_FL MUT TET1Expression of catalytic inactive form of full-length TET1
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124082pEF1a_CD WT TET1Expression of wild-type catalytic domain only form of TET1
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124083pEF1a_CD MUT TET1Expression of mutated catalytic domain only form of TET1
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124084pEF1a_ TET1 CXXC onlyExpression of CXXC domain only form of TET1
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Recombinant Antibodies from Article