YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity.
Yuan Y, Park J, Feng A, Awasthi P, Wang Z, Chen Q, Iglesias-Bartolome R
Nat Commun. 2020 Mar 19;11(1):1472. doi: 10.1038/s41467-020-15301-0. PubMed Article
Yuan Y, Park J, Feng A, Awasthi P, Wang Z, Chen Q, Iglesias-Bartolome R
Nat Commun. 2020 Mar 19;11(1):1472. doi: 10.1038/s41467-020-15301-0. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 140144 | pCEFL EGFP-TEADi | TEAD inhibitor (TEADi): GFP-tagged inhibitor of the interaction of YAP1 and TAZ with TEAD transcription factors with nuclear localization signal. |
| 140145 | pInducer20 EGFP-TEADi | Tetracycline-inducible TEADi (GFP-tagged inhibitor of the interaction of YAP1 and TAZ with TEAD transcription factors with nuclear localization signal) |
| 140146 | pCEFL GAL4dbd-KLF4 1-329 | GAL4-DNA binding domain fusion protein with the 329 N-terminal amino acids of human KLF4 |
| 140147 | pCEFL GAL4dbd-KLF4 1-156 | GAL4-DNA binding domain fusion protein with the 156 N-terminal amino acids of human KLF4 (activation domain) |
| 140148 | pCEFL GAL4dbd-KLF4 159-329 | GAL4-DNA binding domain fusion protein with amino acids 159 to 329 of human KLF4 (repressor domain) |