Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC
Nature. 2020 May;581(7806):100-105. doi: 10.1038/s41586-020-2229-5. Epub 2020 Apr 22. PubMed Article
Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC
Nature. 2020 May;581(7806):100-105. doi: 10.1038/s41586-020-2229-5. Epub 2020 Apr 22. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 161733 | pSLIK_Hyg_mTurquoise2_Atg4BC74A | Doxycycline-inducible expression of Atg4B(C74A) fused with mTurquoise2 to inhibit autophagy |
| 161734 | pINDUCER20_mStrawberry | Doxycycline-inducible expression of mStrawberry |
| 161735 | pINDUCER20_mStrawberry_Atg4BC74A | Doxycycline-inducible expression of Atg4B(C74A) fused with mStrawberry to inhibit autophagy |
| 161736 | pBabe_Zeo_cOVA_T2A_mStrawberry | Expression of cOVA and mStrawberry |
| 161737 | pBabe_Hyg_cOVA_T2A_mStrawberry | Expression of cOVA and mStrawberry |