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Intrinsic disorder controls two functionally distinct dimers of the master transcription factor PU.1.
Xhani S, Lee S, Kim HM, Wang S, Esaki S, Ha VLT, Khanezarrin M, Fernandez GL, Albrecht AV, Aramini JM, Germann MW, Poon GMK
Sci Adv. 2020 Feb 21;6(8):eaay3178. doi: 10.1126/sciadv.aay3178. eCollection 2020 Feb. PubMed Article

Plasmids from Article

ID Plasmid Purpose
199796hPU.1ΔN165-pET28bExpressed human PU.1/Spi-1 ETS domain (residues 165 to 270) in E. coli

Antibodies from Article