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Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation.
Ma J, Lindquist S
Proc Natl Acad Sci U S A 2001 Dec 18;98(26):14955-60. Epub 2001 Dec 11.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
1319moPrP(3F4) D177N
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1321cytosolic moPrP (3F4)
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13917mSecPrP-pCB6+
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Antibodies from Article