Hot Plasmids: FRET-Based Biosensors
Type
Blog Post
...greatest challenges of neuroscience.”
Hot plasmids: Twitch sensors
Griesbeck’s recent contribution to the ...based calcium biosensors. Perhaps most notably, the Twitch calcium sensors, which are available at Addgene...in vivo imaging. Griesbeck explains, while these Twitch sensors are always bright, they change color as...reported in Nature Methods, the FRET changes of these Twitch sensor variants were optimized by testing various... rat hippocampal neuron cultures. The optimized Twitch sensors allowed the researchers to see tonic action...