Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

pCMV5B-Flag-Smad3 Citations (13)

Originally described in: Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2.
Labbe E, Silvestri C, Hoodless PA, Wrana JL, Attisano L Mol Cell. 1998 Jul . 2(1):109-20.
PubMed Journal

Articles Citing pCMV5B-Flag-Smad3

Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signaling. Tran CM, Markova D, Smith HE, Susarla B, Ponnappan RK, Anderson DG, Symes A, Shapiro IM, Risbud MV. Arthritis Rheum. 2010 Jul;62(7):1983-92. doi: 10.1002/art.27445. PubMed
Human myostatin negatively regulates human myoblast growth and differentiation. McFarlane C, Hui GZ, Amanda WZ, Lau HY, Lokireddy S, Xiaojia G, Mouly V, Butler-Browne G, Gluckman PD, Sharma M, Kambadur R. Am J Physiol Cell Physiol. 2011 Jul;301(1):C195-203. doi: 10.1152/ajpcell.00012.2011. Epub 2011 Apr 20. PubMed
ERK5 inhibition ameliorates pulmonary fibrosis via regulating Smad3 acetylation. Kim S, Lim JH, Woo CH. Am J Pathol. 2013 Dec;183(6):1758-68. doi: 10.1016/j.ajpath.2013.08.014. Epub 2013 Oct 1. PubMed
The cancer gene WWOX behaves as an inhibitor of SMAD3 transcriptional activity via direct binding. Ferguson BW, Gao X, Zelazowski MJ, Lee J, Jeter CR, Abba MC, Aldaz CM. BMC Cancer. 2013 Dec 11;13:593. doi: 10.1186/1471-2407-13-593. PubMed
SMAD3 augments FoxO3-induced MuRF-1 promoter activity in a DNA-binding-dependent manner. Bollinger LM, Witczak CA, Houmard JA, Brault JJ. Am J Physiol Cell Physiol. 2014 Aug 1;307(3):C278-87. doi: 10.1152/ajpcell.00391.2013. Epub 2014 Jun 11. PubMed
TGFbeta regulates Galectin-3 expression through canonical Smad3 signaling pathway in nucleus pulposus cells: implications in intervertebral disc degeneration. Tian Y, Yuan W, Li J, Wang H, Hunt MG, Liu C, Shapiro IM, Risbud MV. Matrix Biol. 2016 Mar;50:39-52. doi: 10.1016/j.matbio.2015.11.008. Epub 2015 Nov 27. PubMed
RUNX3-mediated up-regulation of miR-29b suppresses the proliferation and migration of gastric cancer cells by targeting KDM2A. Kong Y, Zou S, Yang F, Xu X, Bu W, Jia J, Liu Z. Cancer Lett. 2016 Oct 10;381(1):138-48. doi: 10.1016/j.canlet.2016.07.038. Epub 2016 Aug 3. PubMed
Hydroxylases regulate intestinal fibrosis through the suppression of ERK-mediated TGF-beta1 signaling. Manresa MC, Tambuwala MM, Radhakrishnan P, Harnoss JM, Brown E, Cavadas MA, Keogh CE, Cheong A, Barrett KE, Cummins EP, Schneider M, Taylor CT. Am J Physiol Gastrointest Liver Physiol. 2016 Dec 1;311(6):G1076-G1090. doi: 10.1152/ajpgi.00229.2016. Epub 2016 Oct 27. PubMed
Binding of coronin 1B to TbetaRI negatively regulates the TGFbeta1 signaling pathway. Kim GY, Lim HJ, Park HY. Biochem Biophys Res Commun. 2017 Aug 19;490(2):574-579. doi: 10.1016/j.bbrc.2017.06.080. Epub 2017 Jun 15. PubMed
Osteocalcin expressing cells from tendon sheaths in mice contribute to tendon repair by activating Hedgehog signaling. Wang Y, Zhang X, Huang H, Xia Y, Yao Y, Mak AF, Yung PS, Chan KM, Wang L, Zhang C, Huang Y, Mak KK. Elife. 2017 Dec 15;6. doi: 10.7554/eLife.30474. PubMed
Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate. Cibi DM, Mia MM, Guna Shekeran S, Yun LS, Sandireddy R, Gupta P, Hota M, Sun L, Ghosh S, Singh MK. Elife. 2019 Jun 26;8. pii: 45418. doi: 10.7554/eLife.45418. PubMed
Smad3 Regulates Neuropilin 2 Transcription by Binding to its 5' Untranslated Region. Xie X, Urabe G, Marcho L, Williams C, Guo LW, Kent KC. J Am Heart Assoc. 2020 Apr 21;9(8):e015487. doi: 10.1161/JAHA.119.015487. Epub 2020 Apr 19. PubMed
SMAD3 promotes expression and activity of the androgen receptor in prostate cancer. Jeon HY, Pornour M, Ryu H, Khadka S, Xu R, Jang J, Li D, Chen H, Hussain A, Fazli L, Gleave M, Dong X, Huang F, Wang Q, Barbieri C, Qi J. Nucleic Acids Res. 2023 Apr 11;51(6):2655-2670. doi: 10.1093/nar/gkad043. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.