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BRAIN Initiative Collection


The Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative aims to revolutionize our knowledge of the human brain through the development and application of innovative tools enabling large-scale real-time interrogation and monitoring of brain cells and circuits during behavior. Long desired by researchers, the revolutionary dynamic picture of the brain generated through this effort will provide novel ways to treat, cure, and even prevent brain disorders.

Brain images from the BRAIN Initiative

The BRAIN Initiative supports the development of a diverse portfolio of biomolecular tools and emphasizes their rapid and broad dissemination to the research community. Browse plasmids, viral preps, and antibodies created with support from the BRAIN Initiative below. Support has been identified by depositors and/or when BRAIN Initiative grants are noted in publications associated with Addgene materials.

Plasmids

ID Plasmid Description PI

Viral Preps

Addgene distributes ready-to-use viral preps made from plasmids in our collection!
AAV are distributed as high-quality and high-titer 100 µL solutions of purified viral particles that are suitable for in vivo use.

ID Viral Prep Description PI
65417-AAV8 pAAV-hSyn-dF-HA-KORD-IRES-mCitrine AAV packaging vector for hSyn driven KOR DREADD expression. Bryan Roth
75033-AAV1 pAAV CD68-hM4D(Gi)-mCherry Expression of hM4D(Gi) using the CD68 promoter. Bryan Roth
83894-AAV1 pAAV-hDlx-Flex-dTomato-Fishell_7 Cre recombinase-dependent dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83894-AAV9 pAAV-hDlx-Flex-dTomato-Fishell_7 Cre recombinase-dependent dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83894-AAVrg pAAV-hDlx-Flex-dTomato-Fishell_7 Cre recombinase-dependent dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83895-AAV1 pAAV-hDlx-Flex-GFP-Fishell_6 Cre recombinase-dependent GFP expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83895-AAV2 pAAV-hDlx-Flex-GFP-Fishell_6 Cre recombinase-dependent GFP expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83895-AAV8 pAAV-hDlx-Flex-GFP-Fishell_6 Cre recombinase-dependent GFP expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83895-AAV9 pAAV-hDlx-Flex-GFP-Fishell_6 Cre recombinase-dependent GFP expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83895-AAVrg pAAV-hDlx-Flex-GFP-Fishell_6 Cre recombinase-dependent GFP expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83896-AAV1 pAAV-hDlx-GiDREADD-dTomato-Fishell-5 Gi-DREADD (P2A) nuclear dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83896-AAV9 pAAV-hDlx-GiDREADD-dTomato-Fishell-5 Gi-DREADD (P2A) nuclear dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83896-AAVrg pAAV-hDlx-GiDREADD-dTomato-Fishell-5 Gi-DREADD (P2A) nuclear dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83897-AAV1 pAAV-hDlx-GqDREADD-dTomato-Fishell-4 Gq-DREADD (P2A) nuclear dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83897-AAV9 pAAV-hDlx-GqDREADD-dTomato-Fishell-4 Gq-DREADD (P2A) nuclear dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83897-AAVrg pAAV-hDlx-GqDREADD-dTomato-Fishell-4 Gq-DREADD (P2A) nuclear dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element Gordon Fishell
83898-AAV1 pAAV-mDlx-ChR2-mCherry-Fishell-3 ChR2-mCherry fusion expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83898-AAV9 pAAV-mDlx-ChR2-mCherry-Fishell-3 ChR2-mCherry fusion expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83898-AAVrg pAAV-mDlx-ChR2-mCherry-Fishell-3 ChR2-mCherry fusion expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83899-AAV1 pAAV-mDlx-GCaMP6f-Fishell-2 GCaMP6f expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83899-AAV9 pAAV-mDlx-GCaMP6f-Fishell-2 GCaMP6f expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83899-AAVrg pAAV-mDlx-GCaMP6f-Fishell-2 GCaMP6f expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83900-AAV1 pAAV-mDlx-GFP-Fishell-1 GFP expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83900-AAV2 pAAV-mDlx-GFP-Fishell-1 GFP expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83900-AAV5 pAAV-mDlx-GFP-Fishell-1 GFP expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83900-AAV8 pAAV-mDlx-GFP-Fishell-1 GFP expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83900-AAV9 pAAV-mDlx-GFP-Fishell-1 GFP expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83900-AAVrg pAAV-mDlx-GFP-Fishell-1 GFP expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
83900-PHPeB pAAV-mDlx-GFP-Fishell-1 GFP expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element Gordon Fishell
99120-AAV1 pAAV-ihSyn1-tTA An AAV genome that expresses tTA from the hSyn1 promoter that contains a positive feedback loop for amplifed expression of the tTA Viviana Gradinaru
99121-AAV1 pAAV-ihSyn1-DIO-tTA An AAV genome with Cre-dependent expression of the tTA from the hSyn1 promoter. Contains a positive feedback loop for amplifed expression of the tTA Viviana Gradinaru
99130-AAV1 pAAV-mDlx-NLS-mRuby2 An AAV genome that expresses nuclear localized mRuby2 from the mouse Dlx5/6 enhancer Viviana Gradinaru
99130-AAV8 pAAV-mDlx-NLS-mRuby2 An AAV genome that expresses nuclear localized mRuby2 from the mouse Dlx5/6 enhancer Viviana Gradinaru
99130-AAV9 pAAV-mDlx-NLS-mRuby2 An AAV genome that expresses nuclear localized mRuby2 from the mouse Dlx5/6 enhancer Viviana Gradinaru
99130-AAVrg pAAV-mDlx-NLS-mRuby2 An AAV genome that expresses nuclear localized mRuby2 from the mouse Dlx5/6 enhancer Viviana Gradinaru
99133-AAV1 pAAV-CAG-fDIO-mNeonGreen An AAV genome with Flp recombinase-dependent expression of mNeonGreen from the CAG promoter Viviana Gradinaru
100798-AAV1 pAAV-syn-FLEX-splitTVA-EGFP-tTA helper virus for monosynaptic tracing; to be coinjected with pAAV-TREtight-mTagBFP2-B19G Ian Wickersham
100799-AAV1 pAAV-TREtight-mTagBFP2-B19G helper virus for monosynaptic tracing; to be coinjected with pAAV-syn-FLEX-splitTVA-EGFP-tTA Ian Wickersham
104052-AAVPHP.V1 pAAV-CAG-DIO-EYFP An AAV genome encoding Cre-dependent expression of the fluorescent protein EYFP from the CAG promoter Viviana Gradinaru
104055-AAV2 pAAV-CAG-eYFP An AAV genome that ubiquitously expresses the fluorescent protein eYFP from the CAG promoter Viviana Gradinaru
104055-AAVrg pAAV-CAG-eYFP An AAV genome that ubiquitously expresses the fluorescent protein eYFP from the CAG promoter Viviana Gradinaru
104055-PHPeB pAAV-CAG-eYFP An AAV genome that ubiquitously expresses the fluorescent protein eYFP from the CAG promoter Viviana Gradinaru
104061-PHPeB CAG-NLS-GFP AAV expression of nuclear localized GFP with SV40 NLS Viviana Gradinaru
105448-AAV9 pAAV-hSyn-DIO-ChrimsonR-mRuby2-ST Cation channelrhodopsin ChrimsonR fused to mRuby2 fluorophore and targeted to the neuronal soma and proximal dendrites in a viral vector Hillel Adesnik
108422-AAV5 pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 AAV production plasmid encoding for Archon1 fluorescent voltage reporter, Cre-dependent expression Edward Boyden
108912-AAV9 pAAV-CAG-DIO-ChroME-ST-P2A-H2B-mRuby3 Cation channelrhodopsin ChroME targeted to the neuronal soma and proximal dendrites and separated from nuclear mRuby3 by P2A in a viral vector Hillel Adesnik
111066-AAV1 pAAV-hSyn-dLight1.1 To generate Adeno-Associated viruses for expression of dLight1.1 under synapsin promoter Lin Tian
111067-AAV1 pAAV-CAG-dLight1.1 To generate Adeno-Associated viruses for expression of dLight1.1 under CAG promoter Lin Tian
111067-AAV5 pAAV-CAG-dLight1.1 To generate Adeno-Associated viruses for expression of dLight1.1 under CAG promoter Lin Tian
111068-AAV1 pAAV-hSyn-dLight1.2 To generate Adeno-Associated viruses for expression of dLight1.2 under synapsin promoter Lin Tian
111068-AAV5 pAAV-hSyn-dLight1.2 To generate Adeno-Associated viruses for expression of dLight1.2 under synapsin promoter Lin Tian
111069-AAV1 pAAV-CAG-dLight1.2 To generate Adeno-Associated viruses for expression of dLight1.1 under CAG promoter Lin Tian
111262-AAV1 pAAV-hSynapsin1-axon-GCaMP6s For enriched expression of GCaMP6s in axons Lin Tian
111568-AAV5 pZac2.1-GfaABC1D-mCherry-hPMCA2w/b Expresses a plasma membrane calcium pump hPMCA2w/b Baljit Khakh
112000-AAV1 pAAV-hSynapsin1-axon-GCaMP6f For enriched expression of GCaMP6f in axons Lin Tian
112004-AAV9 pAAV-hSynapsin1-axon-GCaMP6s-P2A-mKate2 For enriched expression of GCaMP6s in axons with cytosolic expression of mKate2 Lin Tian
112005-AAV5 pAAV-hSynapsin1-axon-GCaMP6s-P2A-mRuby3 For enriched expression of GCaMP6s in axons with cytosolic expression of mRuby3 Lin Tian
112005-AAV9 pAAV-hSynapsin1-axon-GCaMP6s-P2A-mRuby3 For enriched expression of GCaMP6s in axons with cytosolic expression of mRuby3 Lin Tian
112006-AAV9 pAAV-hSynapsin1-GCaMP6s-P2A-mKate2 For co-expression of GCaMP6s with mKate2 Lin Tian
112007-AAV9 pAAV-hSynapsin1-GCaMP6s-P2A-mRuby3 For co-expression of GCaMP6s with mRuby3 Lin Tian
112010-AAV5 pAAV-hSynapsin1-FLEx-axon-GCaMP6s For cre-dependent enriched expression of GCaMP6s in axons Lin Tian
112010-AAV9 pAAV-hSynapsin1-FLEx-axon-GCaMP6s For cre-dependent enriched expression of GCaMP6s in axons Lin Tian
113049-AAV9 pAAV-hSyn-GRAB_DA1m express the genetically-encoded fluorescent dopamine(DA) sensor GRAB_DA1m in neurons Yulong Li
113050-AAV9 pAAV-hSyn-GRAB_DA1h express the genetically-encoded fluorescent dopamine(DA) sensor GRAB_DA1h in neurons Yulong Li
113050-AAVrg pAAV-hSyn-GRAB_DA1h express the genetically-encoded fluorescent dopamine(DA) sensor GRAB_DA1h in neurons Yulong Li
115892-AAV8 pAAV-Syn-Archon1-KGC-GFP-ER2 AAV-mediated expression of Archon1-KGC-GFP-ER2 under the Syn promoter. Using bGHpA signal. Edward Boyden
115893-AAV8 pAAV-Syn-FLEX-rc [Archon1-KGC-GFP-ER2] AAV-mediated expression of Archon1-KGC-GFP-ER2 under the Syn promoter, in floxed/reversed (Cre-dependent) manner. Using bGHpA signal. Edward Boyden
117382-AAV2 hSyn1-eYFP An AAV genome that expresses the fluorescent protein eYFP from the hSyn1 promoter Viviana Gradinaru
117382-AAV5 hSyn1-eYFP An AAV genome that expresses the fluorescent protein eYFP from the hSyn1 promoter Viviana Gradinaru
117382-AAV8 hSyn1-eYFP An AAV genome that expresses the fluorescent protein eYFP from the hSyn1 promoter Viviana Gradinaru
117382-AAV9 hSyn1-eYFP An AAV genome that expresses the fluorescent protein eYFP from the hSyn1 promoter Viviana Gradinaru
117382-AAVrg hSyn1-eYFP An AAV genome that expresses the fluorescent protein eYFP from the hSyn1 promoter Viviana Gradinaru
117382-PHPeB hSyn1-eYFP An AAV genome that expresses the fluorescent protein eYFP from the hSyn1 promoter Viviana Gradinaru
117383-AAV1 TRE-DIO-eYFP An AAV genome with tet-inducible, Cre-dependent expression of the fluorescent protein eYFP Viviana Gradinaru
119741-AAV5 AAV SYN flex PSAM4 GlyR IRES EGFP Chemogenetics Cre-dependent expression plasmid Scott Sternson
119741-AAV9 AAV SYN flex PSAM4 GlyR IRES EGFP Chemogenetics Cre-dependent expression plasmid Scott Sternson
119742-AAV5 AAV SYN PSAM4 GlyR IRES EGFP Chemogenetics expression plasmid Scott Sternson
119744-AAV5 AAV CAMKII PSAM4 GlyR IRES EGFP Chemogenetics expression plasmid Scott Sternson
123308-AAV9 pAAV-hSyn-GRAB_NE1m Expresses the genetically-encoded fluorescent norepinephrine(NE) sensor GRAB_NE1m in neurons Yulong Li
123308-AAVrg pAAV-hSyn-GRAB_NE1m Expresses the genetically-encoded fluorescent norepinephrine(NE) sensor GRAB_NE1m in neurons Yulong Li
123309-AAV9 pAAV-hSyn-GRAB_NE1h Expresses the genetically-encoded fluorescent norepinephrine(NE) sensor GRAB_NE1h in neurons Yulong Li
123309-AAVrg pAAV-hSyn-GRAB_NE1h Expresses the genetically-encoded fluorescent norepinephrine(NE) sensor GRAB_NE1h in neurons Yulong Li
123310-AAV9 pAAV-hSyn-GRAB_NEmut Expresses the genetically-encoded fluorescent norepinephrine(NE) control sensor GRAB_NEmut in neurons Yulong Li
123310-AAVrg pAAV-hSyn-GRAB_NEmut Expresses the genetically-encoded fluorescent norepinephrine(NE) control sensor GRAB_NEmut in neurons Yulong Li
125560-AAV1 pAAV-CAG-dLight1.3b For expression of the genetically encoded dopamine sensor dLight1.3b Lin Tian
125560-AAV5 pAAV-CAG-dLight1.3b For expression of the genetically encoded dopamine sensor dLight1.3b Lin Tian
125560-AAV9 pAAV-CAG-dLight1.3b For expression of the genetically encoded dopamine sensor dLight1.3b Lin Tian
127090-PHPeB pAAV-CAG-DIO-ChR2(H134R)-eYFP Cre-dependent AAV expression of humanized ChR2 (with H134R mutation) fused to eYFP for optogenetic activation Viviana Gradinaru
135420-AAV1 pAAV-syn-FLEX-jYCaMP1s Yellow protein calcium sensor expressed under human Synapsin1 promoter, Cre mediated flip-excision switch, for AAV production or direct transfection, slow variant Kaspar Podgorski
135421-AAV1 pAAV-syn-FLEX-axon-jYCaMP1s Axon-targeted yellow protein calcium sensor expressed under human Synapsin1 promoter, Cre mediated flip-excision switch, for AAV production or direct transfection, slow variant Kaspar Podgorski
135424-AAV1 pAAV-syn-jYCaMP1s Yellow protein calcium sensor expressed under human Synapsin1 promoter, for AAV production or direct transfection, slow variant Kaspar Podgorski
135630-AAV1 pAAV-S5E2-dTom-nlsdTom AAV vector to drive the expression of dTomato in PV cortical interneurons under the control of the E2 regulatory element Jordane Dimidschstein
135630-AAV9 pAAV-S5E2-dTom-nlsdTom AAV vector to drive the expression of dTomato in PV cortical interneurons under the control of the E2 regulatory element Jordane Dimidschstein
135630-PHPeB pAAV-S5E2-dTom-nlsdTom AAV vector to drive the expression of dTomato in PV cortical interneurons under the control of the E2 regulatory element Jordane Dimidschstein
135631-AAV1 pAAV-S5E2-GFP-fGFP AAV vector to drive the expression of fGFP in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135631-PHPeB pAAV-S5E2-GFP-fGFP AAV vector to drive the expression of fGFP in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135632-AAV1 pAAV-S5E2-GCaMP6f AAV vector to drive the expression of GCaMP6f in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135632-AAV9 pAAV-S5E2-GCaMP6f AAV vector to drive the expression of GCaMP6f in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135632-PHPeB pAAV-S5E2-GCaMP6f AAV vector to drive the expression of GCaMP6f in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135633-AAV1 pAAV-S5E2-C1V1-eYFP AAV vector to drive the expression of C1V1-eYFP in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135633-AAV5 pAAV-S5E2-C1V1-eYFP AAV vector to drive the expression of C1V1-eYFP in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135633-AAV9 pAAV-S5E2-C1V1-eYFP AAV vector to drive the expression of C1V1-eYFP in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135633-PHPeB pAAV-S5E2-C1V1-eYFP AAV vector to drive the expression of C1V1-eYFP in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135634-AAV1 pAAV-S5E2-ChR2-mCherry AAV vector to drive the expression of ChR2-mCherry in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135634-AAV9 pAAV-S5E2-ChR2-mCherry AAV vector to drive the expression of ChR2-mCherry in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135634-PHPeB pAAV-S5E2-ChR2-mCherry AAV vector to drive the expression of ChR2-mCherry in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135635-AAV1 pAAV-S5E2-Gq-P2A-dTomato AAV vector to drive the expression of Gq-DREADD-P2A-dTomato in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135635-AAV9 pAAV-S5E2-Gq-P2A-dTomato AAV vector to drive the expression of Gq-DREADD-P2A-dTomato in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135635-PHPeB pAAV-S5E2-Gq-P2A-dTomato AAV vector to drive the expression of Gq-DREADD-P2A-dTomato in PV cortical interneuronsunder the control of the E2 regulatory element Jordane Dimidschstein
135762-AAV9 pAAV-syn-dLight1.3b For expression of the genetically encoded dopamine sensor dLight1.3b Lin Tian
139505-AAV9 pAAV-Ef1a-DIO-PPO-Venus AAV vector for Cre-dependent expression of Venus-tagged parapinopsin driven by the Ef1a promoter. Used for photoswitchable control of inhibitory GPCR signaling cascades. Michael Bruchas
140135-AAV1 pAAV-EF1a-iCreV can be used to generate AAV virus that will express light-inducible site-specific iCreV recombinase Hongkui Zeng
140135-PHPeB pAAV-EF1a-iCreV can be used to generate AAV virus that will express light-inducible site-specific iCreV recombinase Hongkui Zeng
140136-AAV1 pAAV-EF1a-iDreV can be used to generate AAV virus that will expresslight-inducible site-specific iDreV recombinase Hongkui Zeng
140136-PHPeB pAAV-EF1a-iDreV can be used to generate AAV virus that will expresslight-inducible site-specific iDreV recombinase Hongkui Zeng
140137-AAV1 pAAV-EF1a-iFlpV can be used to generate AAV virus that will express light-inducible site-specific iFlpV recombinase Hongkui Zeng
140137-PHPeB pAAV-EF1a-iFlpV can be used to generate AAV virus that will express light-inducible site-specific iFlpV recombinase Hongkui Zeng
140552-AAV9 pAAV-hsyn-GRAB_5-HT1.0 Expresses the 5-HT sensor GRAB_5-HT1.0 in neurons Yulong Li
140553-AAV9 pAAV-hsyn-GRAB_DA2m Expresses the 2nd generation medium-affinity DA sensor GRAB_DA2m in neurons Yulong Li
140554-AAV9 pAAV-hsyn-GRAB_DA2h Expresses the 2nd generation high-affinity DA sensor GRAB_DA2h in neurons Yulong Li
140555-AAV9 pAAV-hsyn-GRAB_DA-mut Expresses the DA-insensitive control sensor GRAB_DA-mut in neurons Yulong Li
140556-AAV9 pAAV-hsyn-GRAB_rDA1m Expresses the red fluorescent medium-affinity DA sensor GRAB_rDA1m in neurons Yulong Li
140557-AAV9 pAAV-hsyn-GRAB_rDA1h Expresses the red fluorescent high-affinity DA sensor GRAB_rDA1h in neurons Yulong Li
140558-AAV9 pAAV-hsyn-GRAB_rDA-mut Expresses the red fluorescent DA-insensitive control sensor GRAB_rDA-mut in neurons Yulong Li
158757-AAV8 pAAV-CAG-SomaGCaMP6f2 Cell body-targeted GCaMP6f, under CAG promoter: GCaMP6f followed by a linker, and the EE-RR coiled coil motif (GCaMP6f-27-EE-RR). As bright as conventional GCaMP6f. Edward Boyden
158757-AAV9 pAAV-CAG-SomaGCaMP6f2 Cell body-targeted GCaMP6f, under CAG promoter: GCaMP6f followed by a linker, and the EE-RR coiled coil motif (GCaMP6f-27-EE-RR). As bright as conventional GCaMP6f. Edward Boyden
163505-PHPeB CN1390-rAAV-DLX2.0-minBG-SYFP2-WPRE3-BGHpA DLX2.0 (3xCore version of DLX enhancer). AAV vector for strong & rapid SYFP2 expression in forebrain GABAergic interneurons. The enhancer core has 100% seq conservation between mouse and human Jonathan Ting
163509-PHPeB CN1839-rAAV-hSyn1-SYFP2-10aa-H2B-WPRE3-BGHpA AAV vector for nuclear SYFP2 labeling in neurons. Useful for nuclear isolation and scRNA-seq applications. Jonathan Ting
164450-PHPeB CN1851-rAAV-hI56i-minBglobin-iCre-4X2C-WPRE3-BGHpA AAV vector for Cre expression in forebrain GABAergic interneurons. For use in combination with Cre-dependent transgenic mouse lines or co-infection with Cre dependent viral vectors. Jonathan Ting
174007-AAV9 pAAV-hSyn-DIO-jGCaMP8s-P2A-ChrimsonR-ST Cre dependent co-expression of jGCaMP8s and soma-targeted ChrimsonR under the control of an hSyn promoter. jGCaMP8s and ChrimsonR are separated by cleavable peptide sequence P2A. Mark Histed
179459-AAV1 pAAV-EF1a-DIO-JEDI-2P-Kv-WPRE Double floxed soma and AIS-localized genetically encoded voltage indicator (GEVI) JEDI-2P in AAV production vector expressed under the mammalian promoter (EF1a) Francois St-Pierre
179460-AAV1 pAAV-EF1a-DIO-JEDI-2P-WPRE Double floxed genetically encoded voltage indicator (GEVI) JEDI-2P in AAV production vector under the control of the mammalian promoter (EF1a) Francois St-Pierre

Antibodies

Addgene distributes ready-to-use recombinant antibodies made from plasmids in our collection!
These monoclonal antibodies are produced in-house and undergo application-specific validation and quality control by Addgene as well as by our trusted partner labs.

ID Recombinant Antibody Reactivity Recommended Applications PI

Additional Resources

  • To learn more, please visit the BRAIN Initiative Resource List.
  • NeuroMab/Trimmer Lab Recombinant mAb Plasmid Collection. The NeuroMab Facility and James Trimmer have produced monoclonal antibodies validated for neuroscience research. The plasmids encoding these antibodies are available at Addgene.
  • AAV Viral Service. Addgene provides a viral service to help facilitate scientific research. Addgene's AAV are made from a selected set of plasmids that are currently in our repository. AAV are distributed as 100 µL of purified viral particles in solution that are suitable for in vivo use.