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Scott Sternson Lab Plasmids


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Title Authors Publication
A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping. Atasoy D, Aponte Y, Su HH, Sternson SM J Neurosci. 2008 Jul 9. 28(28):7025-30.
Chemical and genetic engineering of selective ion channel-ligand interactions. Magnus CJ, Lee PH, Atasoy D, Su HH, Looger LL, Sternson SM Science. 2011 Sep 2;333(6047):1292-6.
Chemogenetic synaptic silencing of neural circuits localizes a hypothalamus-->midbrain pathway for feeding behavior. Stachniak TJ, Ghosh A, Sternson SM Neuron. 2014 May 21;82(4):797-808. doi: 10.1016/j.neuron.2014.04.008. Epub 2014 Apr 24.
Parallel, redundant circuit organization for homeostatic control of feeding behavior. Betley JN, Cao ZF, Ritola KD, Sternson SM Cell. 2013 Dec 5;155(6):1337-50. doi: 10.1016/j.cell.2013.11.002.
A genetically specified connectomics approach applied to long-range feeding regulatory circuits. Atasoy D, Betley JN, Li WP, Su HH, Sertel SM, Scheffer LK, Simpson JH, Fetter RD, Sternson SM Nat Neurosci. 2014 Dec;17(12):1830-9. doi: 10.1038/nn.3854. Epub 2014 Nov 2.
Deconstruction of a neural circuit for hunger. Atasoy D, Betley JN, Su HH, Sternson SM Nature. 2012 Aug 9;488(7410):172-7. doi: 10.1038/nature11270.
Near-Perfect Synaptic Integration by Nav1.7 in Hypothalamic Neurons Regulates Body Weight. Branco T, Tozer A, Magnus CJ, Sugino K, Tanaka S, Lee AK, Wood JN, Sternson SM Cell. 2016 Jun 16;165(7):1749-61. doi: 10.1016/j.cell.2016.05.019.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
18916AAV-FLEX-rev-ChR2(H134R)-mCherryChannelrhodopsin 2-mCherryAAV, Cre/Lox ; Adeno-Associated VirusA FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping. J Neurosci. 2008 Jul 9. 28(28):7025-30. AAV2 Add to Cart
18917AAV-FLEX-rev-ChR2-tdtomatoChannelrhodopsin 2-tdtomatoAAV, Cre/Lox ; Adeno-Associated VirusA FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping. J Neurosci. 2008 Jul 9. 28(28):7025-30. AAV2 Add to Cart
18925pJ241-FLEXFLEX switchCre/Lox ; subcloningA FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping. J Neurosci. 2008 Jul 9. 28(28):7025-30. pJ241 Add to Cart
32474CAG::PSAMQ79G,Q139G:5HT3HC-IRES-GFPPSAMQ79G,Q139G:5HT3 HC (Homo sapiens)Mammalian ExpressionChemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2;333(6047):1292-6. pCAGGS- IRES-GFP Add to Cart
32475rAAV-syn::FLEX-rev::PSAMQ79G,Q139G:5HT3HC-IRES-GFPPSAMQ79G,Q139G-5HT3HC (Homo sapiens)AAV, Cre/Lox ; Adeno-associated virus, FLEX switchChemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2;333(6047):1292-6. AAV2 Add to Cart
32476CAG::PSAML141F,Y115F:5HT3HC-IRES-GFPPSAM Y115F,L141F:5HT3 HC (Homo sapiens)Mammalian ExpressionChemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2;333(6047):1292-6. pCAGGS- IRES-GFP Add to Cart
32477rAAV-syn::FLEX-rev::PSAML141F,Y115F:5HT3HC-IRES-GFPPSAML141F,Y115F-5HT3HC (Homo sapiens)AAV, Cre/Lox ; Adeno-associated virus, FLEX switchChemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2;333(6047):1292-6. AAV2 Add to Cart
32478CAG::PSAML141F:GlyR-IRES-GFPPSAML141F-GlyR (Homo sapiens)Mammalian ExpressionChemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2;333(6047):1292-6. pCAGGS- IRES-GFP Add to Cart
32479rAAV-syn::FLEX-rev::PSAML141F:GlyR-IRES-GFPPSAML141F-GlyR-IRES-GFP (Homo sapiens)AAV, Cre/Lox ; Adeno-associated virus, FLEX switchChemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2;333(6047):1292-6. AAV2 Add to Cart
32480CAG::PSAML141F,Y115F:GlyR-IRES-GFPPSAML141F,Y115F:GlyR (Homo sapiens)Mammalian ExpressionChemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2;333(6047):1292-6. pCAGGS- IRES-GFP Add to Cart
32481rAAV-syn::FLEX-rev::PSAML141F,Y115F:GlyR-IRES-GFPPSAML141F,Y115F-GlyR (Homo sapiens)AAV, Cre/Lox ; Adeno-associated virus, FLEX switchChemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2;333(6047):1292-6. AAV2 Add to Cart
32482CAG::PSAMQ79G:GlyR-IRES-GFPPSAMQ79G-GlyR (Homo sapiens)Mammalian ExpressionChemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2;333(6047):1292-6. pCAGGS-IRES-GFP Add to Cart
52425AAV-FLEX-rev-BFP-2a-TVA-2a-RabiesGTagBFP, TVA receptor, RabiesGAAV, Cre/Lox ; ; Adeno-Associated VirusParallel, redundant circuit organization for homeostatic control of feeding behavior. Cell. 2013 Dec 5;155(6):1337-50. doi: 10.1016/j.cell.2013.11.002. Construct used for viral production of virus expressing the TVA receptor, Rabies protein G and a marker protein TagBFP. AAV2 Add to Cart
52520CAG:: ChR2HA-2a-hM4DChR2-2a-hM4D (Homo sapiens)Mammalian ExpressionChemogenetic synaptic silencing of neural circuits localizes a hypothalamus-->midbrain pathway for feeding behavior. Neuron. 2014 May 21;82(4):797-808. doi: 10.1016/j.neuron.2014.04.008. Epub 2014 Apr 24. Co-expresses HA tagged channelrhodopsin and hM4D M18 Add to Cart
52521AAV-CAG::FLEX-rev:: ChR2HA-2a-hM4DChR2-2a-hM4D (Homo sapiens)AAV, Cre/LoxChemogenetic synaptic silencing of neural circuits localizes a hypothalamus-->midbrain pathway for feeding behavior. Neuron. 2014 May 21;82(4):797-808. doi: 10.1016/j.neuron.2014.04.008. Epub 2014 Apr 24. Co-expresses HA tagged channelrhodopsin and hM4D from a Cre-dependent virus AAV2 Add to Cart
52523CAG:: mCherry-2a-hM4DnrxnmCherry-2a-hM4Dnrxn (Homo sapiens)Mammalian ExpressionChemogenetic synaptic silencing of neural circuits localizes a hypothalamus-->midbrain pathway for feeding behavior. Neuron. 2014 May 21;82(4):797-808. doi: 10.1016/j.neuron.2014.04.008. Epub 2014 Apr 24. Co-expresses hM4Dnrxn and a red fluorescent label M18 Add to Cart
52525CMV:: HA-hM4DnrxnHA-hM4Dnrxn (Homo sapiens)Mammalian Expression, Bacterial ExpressionChemogenetic synaptic silencing of neural circuits localizes a hypothalamus-->midbrain pathway for feeding behavior. Neuron. 2014 May 21;82(4):797-808. doi: 10.1016/j.neuron.2014.04.008. Epub 2014 Apr 24. Expresses N-terminal HA tagged hM4Dnrxn pcDNA5/FRT Add to Cart
52536rAAV-CAG::FLEX-rev:: hM4D-2a-GFPhM4D-2a-GFP (Homo sapiens)AAV, Cre/LoxDeconstruction of a neural circuit for hunger. Nature. 2012 Aug 9;488(7410):172-7. doi: 10.1038/nature11270. Co-expresses hM4D and a green fluorescent label from a Cre-dependent virus AAV2 Add to Cart
60544AA0250-mCherry-2a-hM4D-nrxn1a revmCherry, muscarinic receptor 4, axon targeted variant (Homo sapiens)AAV, Cre/LoxChemogenetic synaptic silencing of neural circuits localizes a hypothalamus-->midbrain pathway for feeding behavior. Neuron. 2014 May 21;82(4):797-808. doi: 10.1016/j.neuron.2014.04.008. Epub 2014 Apr 24. Co-expresses hM4Dnrxn and a red fluorescent label from a Cre-dependent virus AAV2 CHRM4 HM4, M4R Add to Cart
60659AAV-FLEX-VAMP2:HRPVAMP2:HRP (Bos taurus)AAV, Cre/LoxA genetically specified connectomics approach applied to long-range feeding regulatory circuits. Nat Neurosci. 2014 Dec;17(12):1830-9. doi: 10.1038/nn.3854. Epub 2014 Nov 2. Labels synaptic vesicles for electron microscopy AAV-FLEX Add to Cart
79672AAV-FLEX-EGFP-mir30(Scn9a)EGFP (Mus musculus)Mammalian Expression, AAV, Cre/LoxNear-Perfect Synaptic Integration by Nav1.7 in Hypothalamic Neurons Regulates Body Weight. Cell. 2016 Jun 16;165(7):1749-61. doi: 10.1016/j.cell.2016.05.019. Cre-dependent knockdown of Scn9a (Nav1.7) AAV Add to Cart