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viral-service-icon-v3.png Viral Service: Chemogenetics AAV

Use our chemogenetics AAV to chemically induce neuronal activity in specific cell types. See our Chemogenetics Plasmids and Chemogenetics Guide pages for more information about this field.

ID Name Receptor Activity Serotype(s) PI
Syn promoter
44361 pAAV-hSyn-DIO-hM3D(Gq)-mCherry hM3D(Gq) Cre-dependent activation 2, 5, 8, 9, rg*, PHPeB Roth
44362 pAAV-hSyn-DIO-hM4D(Gi)-mCherry hM4D(Gi) Cre-dependent inhibition 2, 5, 8, 9, rg*, PHPeB Roth
50459 pAAV-hSyn-DIO-mCherry none Cre-dependent control 2, 5, 8 Roth
65417 pAAV-hSyn-dF-HA-KORD-IRES-mCitrine kappa-opioid receptor (KOR) Cre-dependent inhibition 8 Roth
50454 pAAV-hSyn-DIO-HA-hM3D(Gq)-IRES-mCitrine hM3D(Gq) Cre-dependent activation 8 Roth
50455 pAAV-hSyn-DIO-HA-hM4D(Gi)-IRES-mCitrine hM4D(Gi) Cre-dependent inhibition 8 Roth
50474 pAAV-hSyn-hM3D(Gq)-mCherry hM3D(Gq) Activation 2, 5, 8, rg* Roth
50475 pAAV-hSyn-hM4D(Gi)-mCherry hM4D(Gi) Inhibition 2, 5, 8, rg* Roth
114472 pAAV-hSyn-mCherry Coming Soon 2, 5, 8 Deisseroth
50465 pAAV-hSyn-EGFP none Control 2, 5, 8, rg* Roth
CaMKIIa promoter
50476 pAAV-CaMKIIa-hM3D(Gq)-mCherry hM3D(Gq) Activation 5, 8 Roth
50477 pAAV-CaMKIIa-hM4D(Gi)-mCherry hM4D(Gi) Inhibition 5, 8 Roth
50469 pAAV-CaMKIIa-EGFP none Control 5, 8 Roth
CD68 promoter
75033 pAAV CD68-hM4D(Gi)-mCherry Coming Soon 1 Roth
GFAP promoter, Non-cre-dependent
50478 pAAV-GFAP-hM3D(Gq)-mCherry hM3D(Gq) Activation 5 Roth
50479 pAAV-GFAP-hM4D(Gi)-mCherry hM4D(Gi) Inhibition 5 Roth

*AAVrg = retrograde serotype, produced with the AAV retro helper plasmid from the Karpova and Schaffer labs. See the Retrograde AAV Inventory Page.

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