Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more


pcDNA3-Casp8 Citations (9)

Originally described in: Biochemical characteristics of caspases-3, -6, -7, and -8.
Stennicke HR, Salvesen GS J Biol Chem. 1997 Oct 10. 272(41):25719-23.
PubMed Journal

Articles Citing pcDNA3-Casp8

Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth. Li C, Egloff AM, Sen M, Grandis JR, Johnson DE. Mol Oncol. 2014 Oct;8(7):1220-30. doi: 10.1016/j.molonc.2014.03.018. Epub 2014 Apr 18. PubMed
EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy. Li YT, Qian XJ, Yu Y, Li ZH, Wu RY, Ji J, Jiao L, Li X, Kong PF, Chen WD, Feng GK, Deng R, Zhu XF. Oncotarget. 2015 Jul 10;6(19):17491-500. PubMed
Sox11 Reduces Caspase-6 Cleavage and Activity. Waldron-Roby E, Hoerauf J, Arbez N, Zhu S, Kulcsar K, Ross CA. PLoS One. 2015 Oct 27;10(10):e0141439. doi: 10.1371/journal.pone.0141439. eCollection 2015. PubMed
Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development. Weaver BP, Weaver YM, Mitani S, Han M. Dev Cell. 2017 Jun 19;41(6):665-673.e6. doi: 10.1016/j.devcel.2017.05.013. Epub 2017 Jun 8. PubMed
VPS34 stimulation of p62 phosphorylation for cancer progression. Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, Qian Z, Lin Z, Li X, Liu X, Jiang L, Yang Y. Oncogene. 2017 Dec 14;36(50):6850-6862. doi: 10.1038/onc.2017.295. Epub 2017 Aug 28. PubMed
Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants. Rehker J, Rodhe J, Nesbitt RR, Boyle EA, Martin BK, Lord J, Karaca I, Naj A, Jessen F, Helisalmi S, Soininen H, Hiltunen M, Ramirez A, Scherer M, Farrer LA, Haines JL, Pericak-Vance MA, Raskind WH, Cruchaga C, Schellenberg GD, Joseph B, Brkanac Z. PLoS One. 2017 Oct 6;12(10):e0185777. doi: 10.1371/journal.pone.0185777. eCollection 2017. PubMed
Herpes Simplex Virus 1 Mutant with Point Mutations in UL39 Is Impaired for Acute Viral Replication in Mice, Establishment of Latency, and Explant-Induced Reactivation. Mostafa HH, Thompson TW, Konen AJ, Haenchen SD, Hilliard JG, Macdonald SJ, Morrison LA, Davido DJ. J Virol. 2018 Mar 14;92(7). pii: JVI.01654-17. doi: 10.1128/JVI.01654-17. Print 2018 Apr 1. PubMed
A Suicide Switch Directly Eliminates Intracellular scFv Oligomers in the Cytoplasm of Mammalian Cells. Nguyen TD, Nagamune T, Kawahara M. Biotechnol J. 2019 Jan;14(1):e1800350. doi: 10.1002/biot.201800350. Epub 2018 Sep 20. PubMed
Injectable cell-encapsulating composite alginate-collagen platform with inducible termination switch for safer ocular drug delivery. Wong FSY, Tsang KK, Chu AMW, Chan BP, Yao KM, Lo ACY. Biomaterials. 2019 May;201:53-67. doi: 10.1016/j.biomaterials.2019.01.032. Epub 2019 Feb 5. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.